bisphosphonate

简明释义

英[bɪsˈfɒsfəneɪt]美[bɪsˈfɑsfəneɪt]

n. 二磷酸盐

英英释义

单词用法

同义词

反义词

例句

1.Importance of calcium co-medication in bisphosphonate therapy of osteoporosis: an approach to improving correct intake and drug adherence.

钙的重要性的共同药物双膦酸盐治疗骨质疏松症：一个正确的方法来提高摄入量和药物遵守。

2.Purpose: Limited data are available on the efficacy of oral bisphosphonate therapy in breast cancer survivors. Our goal was to examine prevention of breast cancer-related bone loss in this cohort.

目的：因为目前关于乳腺癌患者预防性应用双膦酸盐疗效的研究数据比较少，我们此次试验的目的就是研究乳腺癌相关性骨丢失的预防。

3.For patients currently receiving bisphosphonates who require dental procedures, there is no current evidence to suggest that interrupting bisphosphonate therapy will prevent or lower the risk of ONJ.

正在接受双磷酸盐治疗的患者如果需要进行牙科治疗，目前没有证据显示中断双磷酸盐治疗可以防止或降低发生ONJ的风险。

4.There was no significant increase in risk associated with bisphosphonate use, but the study was underpowered for definitive conclusions.

在二膦酸盐的应用过程中，骨折的风险没有明显的增加，但是这些研究还不能得出明确的结论。

5.Bisphosphonate medicines are a common treatment that can be used to slow the effects of the condition.

二膦酸盐药物，是一种常见的治疗可以用来缓慢的影响条件。

6.The Update Committee suggests that bisphosphonate treatment continue for a period of 2 years.

更新委员会建议双磷酸盐治疗持续了2年。

7.The doctor explained that bisphosphonate therapy can reduce the risk of fractures.

医生解释说，二膦酸盐治疗可以降低骨折的风险。

8.Research shows that bisphosphonate can be effective in treating Paget's disease.

研究表明，二膦酸盐在治疗佩吉特病方面是有效的。

9.Patients with osteoporosis are often prescribed bisphosphonate to help strengthen their bones.

患有骨质疏松症的患者通常会被开处方使用二膦酸盐来帮助增强骨骼。

10.Long-term use of bisphosphonate may require regular monitoring of kidney function.

长期使用二膦酸盐可能需要定期监测肾功能。

11.Some patients experience gastrointestinal side effects when taking bisphosphonate medications.

一些患者在服用二膦酸盐药物时会出现胃肠道副作用。

作文

Bisphosphonates are a class of drugs that are primarily used to prevent the loss of bone density. They work by inhibiting the activity of osteoclasts, the cells responsible for bone resorption. This mechanism is particularly beneficial for individuals suffering from osteoporosis, a condition characterized by weak and brittle bones. The use of bisphosphonate (双膦酸盐) therapy has become increasingly common in recent years as awareness of osteoporosis has grown. Osteoporosis can affect anyone, but it is especially prevalent among postmenopausal women. Hormonal changes during menopause lead to an increase in bone resorption, which can result in significant bone loss. By using bisphosphonate (双膦酸盐) medications, patients can help mitigate this risk and maintain their bone health. Commonly prescribed bisphosphonate (双膦酸盐) drugs include alendronate, risedronate, and ibandronate. Patients taking bisphosphonate (双膦酸盐) medications must adhere to specific guidelines to maximize their effectiveness and minimize potential side effects. For example, these drugs are typically taken on an empty stomach with a full glass of water, and patients are advised to remain upright for at least 30 minutes afterward. This helps reduce the risk of gastrointestinal irritation, a common side effect associated with bisphosphonate (双膦酸盐) therapy. While bisphosphonate (双膦酸盐) treatments have proven effective for many, they are not without risks. Some studies have suggested a potential link between long-term use of bisphosphonate (双膦酸盐) medications and rare but serious complications such as osteonecrosis of the jaw and atypical femoral fractures. These concerns underscore the importance of regular medical monitoring and follow-up for patients receiving bisphosphonate (双膦酸盐) therapy. In addition to pharmacological treatment, lifestyle changes play a crucial role in managing osteoporosis. Weight-bearing exercises, a balanced diet rich in calcium and vitamin D, and avoiding smoking and excessive alcohol consumption can significantly enhance bone health. Combining these strategies with bisphosphonate (双膦酸盐) therapy can provide a comprehensive approach to preventing bone loss. As research continues, new formulations and delivery methods for bisphosphonate (双膦酸盐) drugs are being developed, including intravenous options that may offer advantages for certain patients. Understanding the role of bisphosphonate (双膦酸盐) medications in the context of bone health is essential for both healthcare providers and patients. Education about the benefits and risks associated with these drugs can empower individuals to make informed decisions regarding their treatment options. In conclusion, bisphosphonate (双膦酸盐) medications represent a vital tool in the management of osteoporosis and other bone-related conditions. With proper use and ongoing research, these drugs can help millions maintain their bone density and improve their quality of life. Awareness and education surrounding bisphosphonate (双膦酸盐) therapy are key components in the fight against osteoporosis, ensuring that those at risk receive the best possible care.

双膦酸盐是一类主要用于防止骨密度丧失的药物。它们通过抑制负责骨吸收的破骨细胞的活动来发挥作用。这种机制对于患有骨质疏松症的人尤其有益，骨质疏松症是一种以骨骼脆弱和易碎为特征的疾病。近年来，随着人们对骨质疏松症认识的提高，使用双膦酸盐疗法变得越来越普遍。骨质疏松症可以影响任何人，但在绝经后妇女中尤其常见。绝经期间的激素变化导致骨吸收增加，从而可能导致显著的骨量流失。通过使用双膦酸盐药物，患者可以帮助减轻这一风险，保持骨骼健康。常用的双膦酸盐药物包括阿仑膦酸钠、利塞膦酸钠和依班膦酸。服用双膦酸盐药物的患者必须遵循特定的指南，以最大化其效果并最小化潜在副作用。例如，这些药物通常在空腹时与一整杯水一起服用，并建议患者在服用后至少保持直立状态30分钟。这有助于减少胃肠道刺激的风险，这是与双膦酸盐疗法相关的常见副作用。虽然双膦酸盐治疗对许多人有效，但并非没有风险。一些研究表明，长期使用双膦酸盐药物与罕见但严重的并发症（如下颌骨坏死和非典型股骨骨折）之间可能存在潜在联系。这些问题强调了对接受双膦酸盐疗法的患者进行定期医学监测和随访的重要性。除了药物治疗外，生活方式的改变在管理骨质疏松症方面也起着至关重要的作用。负重锻炼、富含钙和维生素D的均衡饮食，以及避免吸烟和过量饮酒，都能显著增强骨骼健康。将这些策略与双膦酸盐疗法结合起来，可以提供一种综合的方法来防止骨质流失。随着研究的不断深入，新的双膦酸盐药物配方和给药方法正在开发中，包括静脉注射选项，这可能为某些患者提供优势。在骨健康的背景下理解双膦酸盐药物的作用对于医疗提供者和患者都是至关重要的。关于这些药物的益处和风险的教育可以使个人在治疗选择上做出明智的决定。总之，双膦酸盐药物在骨质疏松症和其他骨相关疾病的管理中代表了一种重要工具。通过正确使用和持续研究，这些药物可以帮助数百万人维持骨密度，提高生活质量。围绕双膦酸盐疗法的意识和教育是抗击骨质疏松症的关键组成部分，确保那些有风险的人获得最佳护理。