filopodia

简明释义

英[ˌfɪləˈpoʊdiə]美[ˌfɪləˈpoʊdiə]

n. [无脊椎] 丝状伪足

英英释义

单词用法

同义词

反义词

例句

1.The surface of migration cells exhibited numerous filopodia.

迁移细胞表面有众多丝状伪足。

2.The surface of migration cells exhibits affluent pseudopods, which are mainly filopodia.

迁移细胞表面伪足丰富，以丝状伪足为主。

3.When the researchers ramped up the activity of the domain, they saw that the neurons formed the finger-like filopodia which blocked migration by inducing too many branches.

当研究员加速结构域的活动时，他们发现神经细胞形成了指状的丝状伪足，这些丝状伪足形成的分支可以阻止细胞的迁移。

4.When the researchers ramped up the activity of the domain, they saw that the neurons formed the finger-like filopodia which blocked migration by inducing too many branches.

当研究员加速结构域的活动时，他们发现神经细胞形成了指状的丝状伪足，这些丝状伪足形成的分支可以阻止细胞的迁移。

5.Cancer cells often use filopodia 细足 to invade surrounding tissues.

癌细胞通常利用细足侵入周围组织。

6.In wound healing, fibroblasts utilize filopodia 细足 to migrate to the injury site.

在伤口愈合过程中，成纤维细胞利用细足迁移到受伤部位。

7.During neural development, neurons extend filopodia 细足 to explore their environment.

在神经发育过程中，神经元伸展细足以探索其环境。

8.The growth of filopodia 细足 is essential for the movement of amoebas.

变形虫的运动依赖于细足的生长。

9.The study showed that filopodia 细足 play a role in cell signaling.

研究表明，细足在细胞信号传递中发挥作用。

作文

In the realm of cellular biology, the study of cell movement and interaction is crucial for understanding various physiological processes. One fascinating aspect of this field involves structures known as filopodia, which are slender, finger-like projections that extend from the surface of a cell. These projections play a significant role in sensing the environment and facilitating communication between cells. Filopodia are composed of actin filaments and are often found at the leading edge of motile cells, such as neurons and immune cells. Their primary function is to explore the extracellular matrix and guide cell migration during development and wound healing.The formation of filopodia is a highly regulated process that involves the polymerization of actin proteins, which provide structural support and enable the cell to extend its membrane outward. When a cell encounters a suitable substrate or signaling molecules, it can rapidly extend filopodia to probe its surroundings. This exploration is not only vital for movement but also for establishing connections with neighboring cells. For instance, during the development of the nervous system, neurons utilize filopodia to reach out and form synapses with other neurons, ensuring proper communication within the brain.Moreover, filopodia are instrumental in the immune response. Immune cells, such as macrophages and dendritic cells, use these projections to detect pathogens and foreign substances. The presence of filopodia allows these cells to increase their surface area, enhancing their ability to capture and engulf invaders. This process is crucial for initiating an immune response and protecting the body from infections.Recent research has shown that filopodia are not merely passive structures; they actively participate in signaling pathways that influence cell behavior. For example, the extension and retraction of filopodia can be modulated by various growth factors and cytokines, leading to changes in cell migration patterns. Understanding the mechanisms regulating filopodia dynamics is essential for developing therapeutic strategies for diseases characterized by abnormal cell movement, such as cancer metastasis.In conclusion, filopodia are remarkable cellular structures that play a pivotal role in cell motility, communication, and immune responses. Their ability to sense the environment and facilitate interactions between cells underscores their importance in both normal physiological processes and disease states. As research continues to unravel the complexities of filopodia, we gain valuable insights into the fundamental workings of life at the cellular level. The exploration of filopodia not only enhances our understanding of cell biology but also opens new avenues for medical advancements in regenerative medicine and cancer therapy.

在细胞生物学领域，细胞运动和相互作用的研究对于理解各种生理过程至关重要。其中一个迷人的方面涉及被称为filopodia的结构，它们是从细胞表面延伸出的纤细、手指状突起。这些突起在感知环境和促进细胞之间的交流中发挥着重要作用。Filopodia由肌动蛋白纤维组成，通常位于运动细胞的前缘，如神经元和免疫细胞。它们的主要功能是探索细胞外基质并指导细胞在发育和伤口愈合过程中的迁移。Filopodia的形成是一个高度调节的过程，涉及肌动蛋白的聚合，这为细胞提供了结构支持，并使细胞能够向外扩展其膜。当细胞遇到合适的基质或信号分子时，它可以迅速伸展filopodia以探测其周围环境。这种探索不仅对运动至关重要，而且对建立与邻近细胞的连接也至关重要。例如，在神经系统发育过程中，神经元利用filopodia向外伸展并与其他神经元形成突触，从而确保大脑内的正常通信。此外，filopodia在免疫反应中也发挥着重要作用。免疫细胞，如巨噬细胞和树突状细胞，利用这些突起来检测病原体和外来物质。Filopodia的存在使这些细胞能够增加其表面积，从而增强捕获和吞噬入侵者的能力。这一过程对启动免疫反应和保护身体免受感染至关重要。最近的研究表明，filopodia不仅仅是被动结构；它们积极参与影响细胞行为的信号通路。例如，filopodia的伸展和收缩可以通过各种生长因子和细胞因子进行调节，从而导致细胞迁移模式的变化。了解调节filopodia动态的机制对于开发治疗异常细胞运动的疾病（如癌症转移）的策略至关重要。总之，filopodia是显著的细胞结构，在细胞运动、通信和免疫反应中发挥着关键作用。它们感知环境和促进细胞之间相互作用的能力突显了它们在正常生理过程和疾病状态中的重要性。随着研究继续揭示filopodia的复杂性，我们对细胞层面生命基本运作的理解将得到宝贵的深入。对filopodia的探索不仅增强了我们对细胞生物学的理解，还为再生医学和癌症治疗等医学进步开辟了新的途径。