steroidogenic

简明释义

英[ˌstɛrɪoʊdəˈdʒɛnɪk]美[ˌstɛrɪoʊdəˈdʒɛnɪk]

生成类固醇的

英英释义

单词用法

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例句

1.While in the heterozygotic ZW embryo, expression of estrogen receptor, steroidogenic factor-1 and P450 aromatase might stimulate ovarian formation.

在异型配子ZW胚胎中，雌激素受体、类固醇生成因子- 1和P 450芳香化酶基因的表达可刺激卵巢的形成。

2.While in the heterozygotic ZW embryo, expression of estrogen receptor, steroidogenic factor-1 and P450 aromatase might stimulate ovarian formation.

在异型配子ZW胚胎中，雌激素受体、类固醇生成因子- 1和P 450芳香化酶基因的表达可刺激卵巢的形成。

3.The study examined how steroidogenic 类固醇生成的 cells respond to stress.

该研究考察了类固醇生成的细胞如何对压力作出反应。

4.In patients with adrenal insufficiency, the steroidogenic 类固醇生成的 pathways may be disrupted.

在肾上腺功能不全的患者中，类固醇生成的途径可能会受到干扰。

5.Certain tumors can lead to excessive steroidogenic 类固醇生成的 activity, causing hormonal imbalances.

某些肿瘤可能导致过度的类固醇生成的活性，引起激素失衡。

6.Researchers are investigating the genetic factors that influence steroidogenic 类固醇生成的 capacity in different populations.

研究人员正在调查影响不同人群类固醇生成的能力的遗传因素。

7.The research focused on the role of steroidogenic 类固醇生成的 enzymes in hormone production.

该研究集中在类固醇生成的酶在激素生产中的作用。

作文

The term steroidogenic refers to the process by which steroids are produced in the body, particularly in the adrenal glands and gonads. Steroids are organic compounds that play a crucial role in various physiological functions, including metabolism, immune response, and the regulation of inflammation. Understanding the steroidogenic pathways is essential for comprehending how hormones such as cortisol, testosterone, and estrogen are synthesized and their implications on health. In recent years, research has increasingly focused on the significance of steroidogenic activity in relation to various diseases. For example, an imbalance in steroid hormones can lead to conditions such as Cushing's syndrome, which is characterized by excessive cortisol production. This highlights the importance of maintaining proper steroidogenic function within the body to ensure hormonal balance. The process of steroidogenesis begins with cholesterol, which serves as the precursor for all steroid hormones. Cholesterol is transported into the mitochondria of steroidogenic cells, where it undergoes several enzymatic transformations. These transformations are mediated by specific enzymes that convert cholesterol into pregnenolone, the first step in the steroidogenic pathway. From pregnenolone, various steroid hormones are synthesized through different enzymatic reactions. One of the most fascinating aspects of steroidogenic processes is their regulation. Hormonal signals, such as adrenocorticotropic hormone (ACTH) for cortisol production, or luteinizing hormone (LH) for testosterone synthesis, play a vital role in stimulating or inhibiting steroidogenic activity. Dysregulation of these signals can result in hormonal disorders, underscoring the complexity of endocrine regulation in the body. Moreover, environmental factors and lifestyle choices also influence steroidogenic activity. For instance, chronic stress can elevate cortisol levels, leading to long-term health issues. Similarly, obesity has been linked to altered steroid hormone levels, impacting fertility and metabolic health. Thus, understanding the interplay between lifestyle and steroidogenic processes is crucial for developing strategies to promote overall well-being. In conclusion, the concept of steroidogenic is fundamental to our understanding of hormonal biology. The intricate processes involved in steroid hormone production are vital for maintaining homeostasis and regulating numerous bodily functions. Ongoing research into steroidogenic mechanisms holds promise for advancing medical knowledge and therapeutic approaches for various endocrine disorders. As we continue to explore the complexities of hormone regulation, it becomes increasingly clear that a deep understanding of steroidogenic pathways is essential for promoting health and preventing disease.

术语steroidogenic指的是体内类固醇产生的过程，特别是在肾上腺和性腺中。类固醇是有机化合物，在多种生理功能中发挥着关键作用，包括新陈代谢、免疫反应和炎症调节。理解steroidogenic途径对于理解皮质醇、睾酮和雌激素等激素的合成及其对健康的影响至关重要。近年来，研究越来越集中于steroidogenic活性在各种疾病中的重要性。例如，类固醇激素失衡可能导致库欣综合症，其特征是皮质醇过量产生。这突显了维持体内适当steroidogenic功能以确保激素平衡的重要性。类固醇生成的过程始于胆固醇，胆固醇是所有类固醇激素的前体。胆固醇被运输到类固醇生成细胞的线粒体中，在那里经过几个酶促转化。这些转化是由特定酶介导的，将胆固醇转化为孕烯醇酮，这是steroidogenic途径的第一步。从孕烯醇酮开始，通过不同的酶促反应合成各种类固醇激素。steroidogenic过程最引人注目的方面之一是它们的调节。激素信号，如促肾上腺皮质激素（ACTH）用于皮质醇生产，或促黄体生成素（LH）用于睾酮合成，在刺激或抑制steroidogenic活动中发挥着至关重要的作用。这些信号的失调可能导致激素紊乱，强调了体内内分泌调节的复杂性。此外，环境因素和生活方式选择也会影响steroidogenic活动。例如，慢性压力可以提高皮质醇水平，导致长期健康问题。同样，肥胖与类固醇激素水平变化有关，影响生育和代谢健康。因此，理解生活方式与steroidogenic过程之间的相互作用对于制定促进整体健康的策略至关重要。总之，steroidogenic的概念是我们理解激素生物学的基础。类固醇激素生产中涉及的复杂过程对维持稳态和调节众多身体功能至关重要。对steroidogenic机制的持续研究有望推动医学知识和各种内分泌疾病的治疗方法的发展。随着我们继续探索激素调节的复杂性，越来越清楚的是，深入理解steroidogenic途径对于促进健康和预防疾病至关重要。