fumarate

简明释义

英[ˈfjuːməreɪt]美[ˈfjuːməˌreɪt]

n. [有化] 延胡索酸盐；[有化] 延胡索酸酯

英英释义

单词用法

同义词

反义词

例句

1.Soybean oil reduced forage intake by dairy does. Futher supplementation of sodium fumarate did not produce any improvement.

大豆油会降低女羊对粗料的采食，额外补充延胡索酸钠，并没有产生改善的效果。

2.The mainly products of Raw materials of Tianxiang Bio-pharmacy are Tiamulin Fumarate, Tilmicosin Phosphate, Ceftiofur Hydrochloride, Albendazole Oxide, etc.

天象生物主要生产的兽用原料药有延胡索酸泰妙菌素、磷酸替米考星、盐酸头孢噻呋、氧阿笨达唑等。

3.Objective To improve the prescription of Clemastine Fumarate Tablets.

目的改进富马酸氯马斯汀片剂的工艺处方。

4.Thus, the PFR was optimal for immobilized cells to produce L-malic acid in ammonium fumarate system.

因此，在富马酸铵体系中用固定化酶生产L-苹果酸采用填充床反应器更佳。

5.The method is simple, efficient and accurate, and suitable for routine analysis of saccharine sodium, dimethyl fumarate, benzoic acid, and sorbic acid in baked food such as biscuits and moon cakes.

该法简单、快速、准确，可用于饼干、月饼等焙烤食品中糖精钠、富马酸二甲酯、苯甲酸和山梨酸的日常检测。

6.Vitamin C, to increase the absorption of iron fumarate and iron bisglycinate.

维生素C增加富马酸亚铁和葡萄糖酸亚铁的吸收和利用；

7.The enzyme catalyzes the conversion of succinate to fumarate.

该酶催化从琥珀酸转化为富马酸盐。

8.In clinical trials, fumarate derivatives have shown promise for treating multiple sclerosis.

在临床试验中，富马酸盐衍生物在治疗多发性硬化症方面表现出希望。

9.In the Krebs cycle, fumarate is produced from succinyl-CoA.

在克雷布斯循环中，富马酸盐是由琥珀酰辅酶A产生的。

10.The presence of fumarate can indicate certain metabolic disorders.

富马酸盐的存在可能表明某些代谢紊乱。

11.Researchers are studying the effects of fumarate on cellular metabolism.

研究人员正在研究富马酸盐对细胞代谢的影响。

作文

Fumarate is a term that may not be widely recognized outside of scientific circles, yet it plays a crucial role in biochemistry and cellular metabolism. In the human body, fumarate, or 富马酸盐, is an important intermediate in the citric acid cycle, also known as the Krebs cycle. This cycle is essential for energy production and occurs in the mitochondria of cells. Understanding fumarate is vital for grasping how our bodies convert food into energy and how various metabolic disorders can arise when this process is disrupted.The citric acid cycle begins with acetyl-CoA, which is derived from carbohydrates, fats, and proteins. As the cycle progresses, a series of chemical reactions occur, transforming substrates into different compounds. One of these transformations involves the conversion of fumarate into malate through the action of the enzyme fumarase. This step is significant because malate can then be further converted into oxaloacetate, completing the cycle and allowing the process to begin anew.Fumarate itself is formed from the dehydrogenation of succinate by the enzyme succinate dehydrogenase. This reaction is unique because it is the only step in the citric acid cycle that occurs in the inner mitochondrial membrane, linking the citric acid cycle to the electron transport chain. The production of fumarate, therefore, is not just a mere step in a cycle; it has implications for the overall efficiency of energy production within the cell.Moreover, fumarate is not only a key player in energy metabolism but also has implications in health and disease. Elevated levels of fumarate have been associated with certain metabolic disorders, such as fumarate hydratase deficiency, which can lead to serious health complications. This condition is characterized by an accumulation of fumarate in the body, resulting in neurological problems and other systemic issues. Understanding how fumarate functions at a biochemical level can help researchers develop targeted therapies for such conditions.Additionally, fumarate has gained attention in the field of cancer research. It has been discovered that fumarate can act as a signaling molecule, influencing various pathways involved in cell growth and survival. The dysregulation of fumarate and its associated pathways may contribute to tumor development and progression. Therefore, studying fumarate not only enhances our understanding of basic biochemical processes but also opens new avenues for therapeutic intervention in cancer treatment.In conclusion, 富马酸盐 may seem like a simple compound, but its role in cellular metabolism is profound. From its participation in the citric acid cycle to its implications in various health conditions, fumarate exemplifies the complexity of biochemical interactions within the body. As we continue to explore the intricacies of metabolism, fumarate will undoubtedly remain a focal point for both researchers and clinicians alike. By delving deeper into the functions and significance of fumarate, we can better appreciate the delicate balance of biochemical processes that sustain life and inform future medical advancements.