tumorigenesis

简明释义

英[ˌtjuːmərɪˈdʒenɪsɪs]美[ˌtʊmərəˈdʒenɪsɪs;ˌtjʊmərəˈdʒ

n. 肿瘤发生

英英释义

单词用法

同义词

反义词

例句

1.Low dose naltrexone combined with cisplatin, but not taxol, had an additive inhibitory action on tumorigenesis.

低剂量的纳曲酮结合顺铂的治疗方式，有更好的肿瘤抑制作用。

2.To investigate the physiological functions of Sirt2 in development and tumorigenesis, we disrupted Sirt2 in mice.

美国科学家最近通过破坏老鼠的SIRT2基因研究了脱乙酰基酶SIRT2在发育和肿瘤形成中的生理功能。

3.Objective To investigate the effect of interleukin 18 (IL 18) gene transfer on the tumorigenesis of lung carcinoma cell line PG.

目的探讨白细胞介素-18 (IL - 18)基因转导对肺癌细胞系PG细胞肿瘤原性的影响。

4.DNA methylation and its aberrance play an important role in the human development and tumorigenesis.

DNA的甲基化及甲基化异常在人体发育和肿瘤的发生中起着至关重要的作用。

5.These two cells were subcutaneously inoculated into nude mice, and the tumorigenesis was observed.

并将两种细胞接种于裸鼠皮下，观察移植瘤的形成情况。

6.Over recent years research effort has been directed at the regulation of telomere because it is involved in ageing and tumorigenesis.

因端粒与衰老、肿瘤密切相关，近年来对端粒调节的研究进一步深入。

7.This paper focus on the role of the homeobox gene in gastrointestinal development and tumorigenesis.

此文对同源盒基因在胃肠道发育及胃肠道肿瘤发生中的作用作一综述。

8.The role of genetics in tumorigenesis is a critical area of cancer research.

遗传学在肿瘤发生中的作用是癌症研究的一个关键领域。

9.Understanding tumorigenesis can help in identifying early biomarkers for cancer detection.

理解肿瘤发生可以帮助识别癌症检测的早期生物标志物。

10.Certain environmental factors are known to influence tumorigenesis in various types of cancer.

某些环境因素被认为会影响各种类型癌症的肿瘤发生。

11.The study of tumorigenesis involves complex interactions between cells and their microenvironment.

对肿瘤发生的研究涉及细胞与其微环境之间的复杂相互作用。

12.Researchers are studying the mechanisms of tumorigenesis to develop new cancer therapies.

研究人员正在研究肿瘤发生的机制，以开发新的癌症治疗方法。

作文

Tumorigenesis, or the process of tumor formation, is a complex and multifaceted phenomenon that has captivated the attention of researchers and medical professionals for decades. Understanding tumorigenesis (肿瘤发生) is crucial for developing effective treatments and preventive strategies against cancer. The journey of a normal cell transforming into a malignant tumor involves a series of genetic mutations and environmental influences that disrupt the delicate balance of cellular regulation.At its core, tumorigenesis (肿瘤发生) begins with genetic alterations. These changes can be inherited or acquired due to various factors such as exposure to carcinogens, radiation, or viral infections. For instance, mutations in genes that regulate cell growth and division can lead to uncontrolled proliferation, a hallmark of cancer. The activation of oncogenes and the inactivation of tumor suppressor genes are critical events in this process. Oncogenes promote cell division, while tumor suppressor genes act as brakes to prevent excessive growth. When these regulatory mechanisms fail, cells can begin to grow uncontrollably, leading to the formation of tumors.In addition to genetic factors, environmental influences play a significant role in tumorigenesis (肿瘤发生). Lifestyle choices such as smoking, diet, and physical activity can either increase or decrease the risk of developing cancer. For example, tobacco smoke contains numerous carcinogenic compounds that can initiate the genetic changes necessary for tumorigenesis (肿瘤发生). Similarly, a diet high in processed foods and low in fruits and vegetables may contribute to the development of certain cancers by promoting inflammation and oxidative stress.The microenvironment surrounding a tumor also contributes to tumorigenesis (肿瘤发生). Tumors do not exist in isolation; they interact with various cells, signaling molecules, and blood vessels in their vicinity. This interaction can create a supportive environment that fosters tumor growth and progression. For instance, cancer cells can secrete factors that recruit immune cells to the tumor site, but instead of attacking the cancer, these immune cells may inadvertently aid in its growth. Understanding these interactions is essential for developing targeted therapies that can disrupt this supportive microenvironment.Research into tumorigenesis (肿瘤发生) has led to significant advancements in cancer treatment. Targeted therapies that specifically inhibit the pathways involved in tumor growth have emerged as promising options for patients. For example, drugs that target specific mutations in oncogenes have shown remarkable efficacy in treating certain types of cancer. Additionally, immunotherapy, which harnesses the body’s immune system to fight cancer, has revolutionized the way we approach cancer treatment.In conclusion, tumorigenesis (肿瘤发生) is a complex process influenced by genetic, environmental, and microenvironmental factors. A deeper understanding of this phenomenon is essential for the development of effective cancer prevention and treatment strategies. As research continues to unravel the intricacies of tumorigenesis (肿瘤发生), we move closer to a future where cancer can be effectively managed and potentially cured.

肿瘤发生，即肿瘤形成的过程，是一个复杂且多面的现象，几十年来一直吸引着研究人员和医疗专业人士的关注。理解tumorigenesis（肿瘤发生）对开发有效的癌症治疗和预防策略至关重要。正常细胞转变为恶性肿瘤的过程涉及一系列遗传突变和环境影响，这些因素打破了细胞调节的微妙平衡。从根本上说，tumorigenesis（肿瘤发生）始于遗传改变。这些变化可以是遗传的，也可以是由于接触致癌物、辐射或病毒感染等各种因素而获得的。例如，调节细胞生长和分裂的基因突变可能导致失控增殖，这是癌症的标志。癌基因的激活和肿瘤抑制基因的失活是这一过程中至关重要的事件。癌基因促进细胞分裂，而肿瘤抑制基因则作为刹车，以防止过度生长。当这些调节机制失效时，细胞可能开始失控生长，从而导致肿瘤的形成。除了遗传因素外，环境影响在tumorigenesis（肿瘤发生）中也发挥着重要作用。生活方式选择，如吸烟、饮食和身体活动，可以增加或降低癌症发展的风险。例如，烟草烟雾中含有大量致癌化合物，这些化合物可以引发肿瘤发生所需的遗传变化。同样，高加工食品和低水果蔬菜饮食可能通过促进炎症和氧化应激来促进某些癌症的发展。肿瘤周围的微环境也对tumorigenesis（肿瘤发生）产生影响。肿瘤并不是孤立存在的；它们与周围的各种细胞、信号分子和血管相互作用。这种相互作用可以创造一个支持肿瘤生长和进展的环境。例如，癌细胞可以分泌因素，招募免疫细胞到肿瘤部位，但这些免疫细胞可能会意外地帮助肿瘤生长，而不是攻击癌症。理解这些相互作用对于开发能够破坏这种支持性微环境的靶向疗法至关重要。对tumorigenesis（肿瘤发生）的研究已导致癌症治疗的重要进展。专门抑制肿瘤生长相关途径的靶向疗法已成为患者的有希望的选择。例如，针对特定癌基因突变的药物在治疗某些类型癌症方面显示出显著疗效。此外，免疫疗法利用身体的免疫系统对抗癌症，彻底改变了我们对癌症治疗的看法。总之，tumorigenesis（肿瘤发生）是一个受遗传、环境和微环境因素影响的复杂过程。深入了解这一现象对于开发有效的癌症预防和治疗策略至关重要。随着研究继续揭示tumorigenesis（肿瘤发生）的复杂性，我们离一个能够有效控制和可能治愈癌症的未来越来越近。