chloramphenicol

简明释义

英[ˌklɔːræmˈfenɪkɒl]美[ˌklɔːræmˈfenəˌkoʊl]

n. [药] 氯霉素

英英释义

单词用法

同义词

反义词

例句

1.Objective: To establish the for quality control of Metronidazole Chloramphenicol Liniment.

目的：建立氯霉素甲硝唑搽剂质量控制方法。

2.OBJECTIVE To study the stability of Chloramphenicol eye drop and improve its formulation and preparation.

目的研究氯霉素滴眼液的稳定性，改进其处方工艺。

3.Objective: to establish a method to determine the content of chloramphenicol in chloramphenicol lotion compound.

目的：建立复方氯霉素洗剂中氯霉素的含量测定方法。

4.Method: Determines the interference of chloramphenicol glucose injection to endotoxin with the endotoxin Analyzer.

方法：用细菌内毒素测定仪考察氯霉素葡萄糖注射液对细菌内毒素的干扰。

5.Objectives: To determine the content of chloramphenicol tincture compound.

目的：对复方氯霉素酊的含量测定进行研究。

6.Objective: To investigate the preparation of compound ear pills of chloramphenicol.

目的：制备复方氯霉素耳用滴丸并观察其临床疗效。

7.Before administering chloramphenicol, the nurse checked for any allergies.

在给药之前，护士检查了是否有对氯霉素的过敏史。

8.The patient was informed about the potential risks associated with chloramphenicol use.

患者被告知使用氯霉素可能带来的风险。

9.The doctor prescribed chloramphenicol for the patient's eye infection.

医生为患者的眼部感染开了氯霉素。

10.Due to its effectiveness, chloramphenicol is often used to treat typhoid fever.

由于其有效性，氯霉素常用于治疗伤寒。

11.Some countries have restricted the use of chloramphenicol due to its side effects.

由于副作用，一些国家限制了氯霉素的使用。

作文

Chloramphenicol is an antibiotic that was first discovered in the 1940s. It is derived from the bacterium Streptomyces venezuelae and has been used to treat a variety of bacterial infections. One of the remarkable aspects of chloramphenicol is its ability to penetrate tissues and reach areas that other antibiotics may not effectively target. This makes it particularly useful in treating serious infections such as typhoid fever and certain types of meningitis. However, with great power comes great responsibility, and the use of chloramphenicol is not without its risks.The mechanism of action of chloramphenicol involves inhibiting bacterial protein synthesis. It achieves this by binding to the 50S subunit of the bacterial ribosome, thereby preventing the peptide bond formation necessary for protein production. This action not only disrupts the growth of bacteria but can also lead to cell death if the bacteria are unable to produce essential proteins. While this makes chloramphenicol effective against a wide range of bacteria, it also raises concerns about its potential side effects.One of the most significant concerns regarding chloramphenicol is its association with aplastic anemia, a rare but serious condition where the bone marrow fails to produce sufficient blood cells. This side effect has led to restrictions on its use in many countries. Doctors typically reserve chloramphenicol for situations where other antibiotics are ineffective or impractical. Additionally, it is crucial to monitor patients closely while they are on this medication to detect any early signs of adverse reactions.Despite these risks, chloramphenicol remains an important tool in the arsenal of antibiotics. Its broad spectrum of activity makes it a valuable option when treating infections caused by resistant strains of bacteria. In some developing countries, chloramphenicol is still used extensively due to its low cost and effectiveness. However, healthcare providers must weigh the benefits against the potential risks when considering its use.In recent years, there has been a growing trend towards the development of new antibiotics that can combat drug-resistant bacteria. While chloramphenicol has been overshadowed by newer drugs, its historical significance cannot be understated. It was one of the first antibiotics to be synthesized and paved the way for the development of many others. Understanding the history and application of chloramphenicol helps us appreciate the complexity of antibiotic therapy and the ongoing battle against bacterial infections.In conclusion, chloramphenicol is a powerful antibiotic with a rich history and a unique role in modern medicine. Its ability to treat severe infections is counterbalanced by the potential for serious side effects. As we continue to face challenges with antibiotic resistance, the lessons learned from the use of chloramphenicol will be invaluable in guiding future research and clinical practice. The careful use of this antibiotic can help ensure that it remains a viable option for treating bacterial infections in the years to come.

氯霉素是一种抗生素，最早在20世纪40年代被发现。它源自细菌Streptomyces venezuelae，并已被用于治疗多种细菌感染。氯霉素的一个显著特点是其能够穿透组织并到达其他抗生素可能无法有效靶向的区域。这使得它在治疗严重感染（如伤寒和某些类型的脑膜炎）时特别有用。然而，强大的药物也伴随着巨大的责任，氯霉素的使用并非没有风险。氯霉素的作用机制涉及抑制细菌蛋白质合成。它通过与细菌核糖体的50S亚基结合，阻止必需的肽键形成，从而妨碍蛋白质的产生。这一作用不仅干扰了细菌的生长，还可能导致细菌死亡，因为它们无法生产必需的蛋白质。虽然这使得氯霉素对广泛的细菌有效，但也引发了对其潜在副作用的担忧。关于氯霉素的一个重要担忧是它与再生障碍性贫血的关联，这是一种罕见但严重的疾病，骨髓无法产生足够的血细胞。这一副作用导致许多国家限制其使用。医生通常将氯霉素保留用于其他抗生素无效或不切实际的情况。此外，在患者使用该药物期间，密切监测至关重要，以便及时发现任何早期不良反应的迹象。尽管存在这些风险，氯霉素仍然是抗生素武器库中的一个重要工具。其广谱活性使其在治疗耐药细菌感染时成为有价值的选择。在一些发展中国家，由于其低成本和有效性，氯霉素仍被广泛使用。然而，医疗提供者必须在考虑使用时权衡利弊。近年来，开发新抗生素以对抗耐药细菌的趋势日益增长。尽管氯霉素已被更新药物所掩盖，但其历史意义不可低估。它是第一批合成的抗生素之一，为许多其他抗生素的发展铺平了道路。了解氯霉素的历史和应用有助于我们欣赏抗生素疗法的复杂性以及与细菌感染作斗争的持续挑战。总之，氯霉素是一种强效抗生素，具有丰富的历史和现代医学中的独特角色。它治疗严重感染的能力与严重副作用的潜在风险相抵消。随着我们继续面临抗生素耐药性挑战，从氯霉素的使用中获得的经验教训对未来的研究和临床实践将是无价的。谨慎使用这种抗生素可以帮助确保它在未来几年仍然是治疗细菌感染的可行选择。