papaverine

简明释义

英[pəˈpeɪvəˌriːn]美[pəˈpævəˌriːn]

n. [药] 罂粟碱

英英释义

单词用法

同义词

反义词

例句

1.To observe the clinical efficacy of papaverine-nitroglycerin ointment on the treatment of.

观察罂硝软膏治疗静脉炎的临床疗效。

2.To observe the clinical efficacy of papaverine-nitroglycerin ointment on the treatment of.

观察罂硝软膏治疗静脉炎的临床疗效。

3.After taking papaverine, the patient reported a significant reduction in pain.

服用罂粟碱后，病人报告疼痛明显减轻。

4.The doctor prescribed papaverine to relieve the patient's muscle spasms.

医生开了罂粟碱来缓解病人的肌肉痉挛。

5.Research indicates that papaverine may help treat erectile dysfunction.

研究表明罂粟碱可能有助于治疗勃起功能障碍。

6.In clinical trials, papaverine was shown to improve blood flow in patients with vascular disorders.

在临床试验中，罂粟碱被证明能改善血管疾病患者的血流。

7.The pharmacist explained that papaverine can be used as a vasodilator.

药剂师解释说罂粟碱可以用作血管扩张剂。

作文

Papaverine is a well-known alkaloid derived from the opium poppy, Papaver somniferum. It has been used for many years in medicine primarily as a smooth muscle relaxant. The discovery of papaverine was significant in the field of pharmacology, as it opened new doors for treating various conditions related to smooth muscle spasms. For instance, papaverine is often used to alleviate symptoms associated with gastrointestinal disorders, such as irritable bowel syndrome, where muscle tension can lead to discomfort and pain.In addition to its use in gastrointestinal issues, papaverine has also found applications in urology. It is sometimes prescribed to treat erectile dysfunction by promoting vasodilation, which increases blood flow to the penis. This effect is particularly important for men who may have underlying vascular issues that hinder their ability to achieve or maintain an erection. The mechanism by which papaverine works involves inhibiting phosphodiesterase, an enzyme that breaks down cyclic AMP, leading to increased levels of this important signaling molecule in the body.Moreover, papaverine has been utilized in neurology, particularly in the treatment of cerebral vasospasm, a condition that can occur after subarachnoid hemorrhage. By relaxing the smooth muscles in the blood vessels of the brain, papaverine can help restore normal blood flow and reduce the risk of further complications.Despite its benefits, the use of papaverine is not without risks. Patients may experience side effects such as dizziness, flushing, and gastrointestinal disturbances. Furthermore, the potential for drug interactions must be carefully considered, especially in patients taking medications for cardiovascular conditions. Therefore, it is essential for healthcare providers to assess the patient's overall health status and medication regimen before prescribing papaverine.As research continues, scientists are exploring new formulations and delivery methods for papaverine. Innovations in drug delivery systems could enhance its efficacy and minimize side effects. For example, targeted delivery methods may allow for localized treatment of specific tissues, reducing systemic exposure and associated risks.In conclusion, papaverine remains a valuable medication in the therapeutic arsenal against various smooth muscle-related conditions. Its historical significance and ongoing relevance in modern medicine highlight the importance of understanding both its benefits and limitations. As we look to the future, continued research into papaverine and its mechanisms of action will likely yield new insights and potential applications, ultimately improving patient outcomes across multiple medical disciplines.

罂粟碱是从罂粟植物（Papaver somniferum）中提取的一种著名生物碱。多年来，它主要作为平滑肌松弛剂在医学上得到应用。papaverine的发现对药理学领域具有重要意义，因为它为治疗与平滑肌痉挛相关的各种病症打开了新大门。例如，papaverine通常用于缓解与胃肠道疾病相关的症状，如肠易激综合症，在这种情况下，肌肉紧张可能导致不适和疼痛。除了在胃肠问题上的应用，papaverine还在泌尿学中找到了用武之地。它有时被开用于治疗勃起功能障碍，通过促进血管扩张来增加阴茎的血流。这一效果对于那些可能存在基础血管问题、妨碍他们达到或维持勃起的男性尤为重要。papaverine的作用机制涉及抑制磷酸二酯酶，这是一种分解环磷酸腺苷的酶，从而导致体内这一重要信号分子的水平升高。此外，papaverine还在神经学中被利用，特别是在治疗脑血管痉挛方面，这种情况可能发生在蛛网膜下腔出血后。通过放松大脑血管的平滑肌，papaverine可以帮助恢复正常的血流，减少进一步并发症的风险。尽管有其益处，使用papaverine也并非没有风险。患者可能会经历如头晕、潮红和胃肠道不适等副作用。此外，必须仔细考虑潜在的药物相互作用，尤其是在接受心血管疾病治疗的患者中。因此，医疗提供者在开处方papaverine之前，评估患者的整体健康状况和用药情况至关重要。随着研究的不断深入，科学家们正在探索papaverine的新配方和给药方法。药物递送系统的创新可能会增强其疗效并最小化副作用。例如，靶向递送方法可能允许对特定组织进行局部治疗，减少全身暴露及相关风险。总之，papaverine在治疗各种平滑肌相关疾病方面仍然是一种宝贵的药物。其历史意义和在现代医学中的持续相关性突显了理解其益处和局限性的重要性。展望未来，对papaverine及其作用机制的持续研究可能会带来新的见解和潜在的应用，最终改善多个医学领域的患者结果。