pilocarpine

简明释义

英[/ˌpɪloʊˈkɑːrpiːn/]美[/ˌpɪloʊˈkɑːrpiːn/]

n. 匹鲁卡品；毛果芸香碱（一种眼科缩瞳药）

英英释义

单词用法

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例句

1.Research and development the new dosage form of nitrate Pilocarpine, to provide a safe, reliable and effective sustained release drugs on the treatment of glaucoma.

开发、研制硝酸毛果芸香碱新剂型，为青光眼的治疗提供安全、可靠、有效的缓释药物。

2.Objective To compare the myotic effects of physostigmine, pilocarpine and neostigmine in rabbits.

目的比较新斯的明、毒扁豆碱和毛果芸香碱对兔眼的缩瞳作用。

3.The lithium-pilocarpine induced SE was used as the SE model.

建立氯化锂-匹罗卡品大鼠SE模型。

4.Aim: To explore the early phase change of oligodendrocyte precursor cells in the brain of epileptic rats induced by chloride lithium-pilocarpine.

目的：探讨氯化锂毛果芸香碱(匹罗卡品)致疒间大鼠早期大脑少突胶质前体细胞变化及意义。

5.Objective to explore the gene expression of myelin transcription factor 1 and its significance in brain of epileptic rats induced by chloride lithium-pilocarpine.

目的探讨氯化锂-匹罗卡品致癫大鼠脑髓鞘转录因子1基因表达变化及其意义。

6.RESULTS: Neuron necrosis, apoptosis, increase of apoptosis protein expression and proliferation of glial cells were the characteristics of pathological injury in the pilocarpine induced se models.

结果：毛果芸香碱惊厥持续状态模型鼠病理损伤特点为神经元坏死、细胞凋亡、凋亡蛋白表达增多，胶质细胞增生。

7.During the clinical trial, participants received pilocarpine to assess its effectiveness.

在临床试验中，参与者接受了匹罗卡品以评估其有效性。

8.Patients with Sjögren’s syndrome often benefit from pilocarpine to relieve symptoms.

患有舍格伦综合症的患者通常会从匹罗卡品中受益，以缓解症状。

9.In glaucoma treatment, pilocarpine is used to lower intraocular pressure.

在青光眼治疗中，匹罗卡品用于降低眼内压力。

10.The side effects of pilocarpine may include sweating and increased salivation.

匹罗卡品的副作用可能包括出汗和唾液分泌增加。

11.The doctor prescribed pilocarpine to help increase saliva production in patients with dry mouth.

医生开了匹罗卡品来帮助增加口腔干燥患者的唾液分泌。

作文

In the field of medicine, there are numerous compounds and substances that play critical roles in treating various conditions. One such compound is pilocarpine, which is derived from the leaves of the jaborandi plant, native to South America. This alkaloid has been used for many years in the treatment of specific medical conditions, particularly those affecting the eyes and salivary glands. Understanding the mechanism and applications of pilocarpine can provide valuable insights into its importance in therapeutic practices.Pilocarpine is primarily known for its ability to stimulate the secretion of saliva and sweat. It acts as a muscarinic agonist, meaning it binds to and activates muscarinic receptors in the body. This action leads to increased glandular secretions, making pilocarpine particularly useful for patients suffering from dry mouth, a condition often resulting from certain medications or diseases such as Sjögren's syndrome. For these individuals, the administration of pilocarpine can significantly improve their quality of life by alleviating discomfort associated with dry oral mucosa.In addition to its effects on salivary glands, pilocarpine is also employed in ophthalmology. It is used to treat glaucoma, a condition characterized by elevated intraocular pressure that can lead to vision loss. By activating the muscarinic receptors in the eye, pilocarpine promotes the outflow of aqueous humor, thereby reducing intraocular pressure. This mechanism is crucial in managing glaucoma and preventing its potentially devastating consequences.The versatility of pilocarpine extends beyond these applications. Researchers are continually exploring its potential in other areas of medicine. For instance, studies have indicated that pilocarpine may have neuroprotective effects, which could be beneficial in treating neurodegenerative diseases such as Alzheimer's. The ability of pilocarpine to enhance cholinergic activity in the brain opens new avenues for research and potential therapeutic strategies.Despite its benefits, the use of pilocarpine is not without challenges. Patients may experience side effects, including sweating, nausea, and gastrointestinal disturbances. Therefore, healthcare providers must carefully consider the dosage and monitor patients for any adverse reactions. Furthermore, pilocarpine is contraindicated in certain conditions, such as asthma or other respiratory issues, where its stimulating effects on secretions may exacerbate symptoms.In conclusion, pilocarpine is a valuable pharmaceutical agent with significant applications in treating dry mouth and glaucoma. Its unique properties as a muscarinic agonist allow it to effectively stimulate glandular secretions and reduce intraocular pressure. As research continues to unveil its potential benefits in other medical fields, the importance of pilocarpine in modern medicine cannot be overstated. Understanding this compound not only highlights its therapeutic uses but also emphasizes the ongoing need for research into its broader implications in healthcare. By recognizing the role of pilocarpine, we appreciate the intricate connections between natural compounds and their therapeutic applications, ultimately enhancing patient care and treatment outcomes.

匹罗卡品是一种重要的药物成分，广泛应用于医学领域。它源自南美的某种植物的叶子，具有刺激唾液和汗液分泌的功能，尤其对干口症患者非常有效。同时，匹罗卡品也用于治疗青光眼，通过降低眼内压来保护视力。尽管有许多好处，但使用时也需注意副作用及禁忌症。随着研究的深入，匹罗卡品在其他医学领域的潜力也在不断被发掘，显示了自然化合物与治疗应用之间的复杂联系。