racemization
简明释义
英[ˌræsəmɪˈzeɪʃən]美[ˌræsəmɪˈzeɪʃən]
n. [化学] 外消旋作用
英英释义
Racemization is the process of converting an optically active compound into a racemic mixture, which contains equal amounts of both enantiomers. | 消旋化是将一个光学活性化合物转化为外消旋混合物的过程,该混合物包含两种对映体的等量。 |
单词用法
外消旋化反应 | |
完全外消旋化 | |
部分外消旋化 | |
经历外消旋化 | |
防止外消旋化 | |
监测外消旋化 |
同义词
消旋化 | The process of racemization can affect the pharmacological properties of drugs. | 消旋化过程可能影响药物的药理特性。 | |
对映体化 | Enantiomerization is critical in the synthesis of chiral compounds. | 对映体化在手性化合物的合成中至关重要。 |
反义词
分解 | The resolution of the compound led to the formation of a single enantiomer. | 该化合物的分解导致了单一对映体的形成。 | |
不对称 | Asymmetry in molecular structure is crucial for biological activity. | 分子结构的不对称性对生物活性至关重要。 |
例句
1.Racemization is found with optically active substrates.
发现旋光基质有外消旋作用。
2.Dynamic resolution technology combines the resolution with racemization in situ.
动态拆分技术是将拆分反应与现场消旋化反应相结合的技术。
3.The dependence of chain scission and racemization on temperature results from molecular motion, "cage effect" and steric hindrance during recombination.
分子量降低和消旋作用对温度的依赖性,是由于分子运动和笼罩效应以及重合的空间位阻效应所致。
4.The invention discloses a method for the racemization of sertraline isomer.
本发明公开了一种外消旋化舍曲林异构体的方法。
5.The mechanism of the racemization was discussed.
同时也论述了氨基酸消旋的反应机理。
6.By analyzing how much racemization of its aspartic acid occurred, scientists can determine how old the tooth's owner was at death - generally accurate to about 5.5 years, plus or minus 4.2 years.
通过分析其天冬氨酸发生了多少外消旋化,科学家可以确定牙齿主人在多大岁数死亡——通常精确到5年半左右,正负差4.2年。
7.However, when the researchers applied both techniques to teeth, they realized that the racemization offered an additional useful detail, a good gauge of an individual's age at death.
然而,当研究人员将两项技术一并运用于牙齿上,他们意识到外消旋化提供了一个额外的有用细节,能成为个体死亡年龄的良好衡量标准。
8.The process of racemization is crucial in understanding how certain drugs behave in the body.
理解某些药物在体内的行为时,消旋化的过程至关重要。
9.Scientists are studying the racemization rates of amino acids in ancient fossils.
科学家正在研究古代化石中氨基酸的消旋化速率。
10.The racemization of sugars can lead to the formation of unwanted byproducts in food processing.
糖类的消旋化可能导致食品加工中产生不必要的副产品。
11.Understanding racemization is essential for developing more effective pharmaceuticals.
理解消旋化对开发更有效的药物至关重要。
12.In organic chemistry, racemization can affect the efficacy of chiral catalysts.
在有机化学中,消旋化可能影响手性催化剂的效力。
作文
Racemization is a process that plays a significant role in the field of chemistry, particularly in the study of chiral molecules. Chiral molecules are compounds that exist in two forms that are mirror images of each other, known as enantiomers. These enantiomers can have very different biological activities, making the understanding of processes like racemization crucial for drug development and other applications. Racemization refers to the conversion of one enantiomer into another, resulting in a mixture of both forms. This process can occur naturally or can be induced by various factors such as temperature, pH, or the presence of catalysts.In the pharmaceutical industry, racemization can significantly impact the efficacy and safety of drugs. For instance, one enantiomer of a drug may be therapeutically active while the other could be inactive or even harmful. The racemization of these enantiomers during storage or metabolism can lead to unexpected side effects or reduced effectiveness of the medication. Therefore, understanding the conditions that promote racemization is essential for chemists and pharmacologists.Furthermore, racemization is not only important in pharmaceuticals but also in the food industry. Certain flavors and aromas are derived from chiral compounds, and their racemization can alter the sensory properties of food products. For example, the flavor profile of certain fruits can change due to the racemization of specific compounds during ripening or processing. This highlights the importance of controlling racemization in food production to ensure consistent quality and taste.Moreover, racemization has implications in environmental science as well. In nature, many natural products undergo racemization, which can affect the behavior and fate of these compounds in ecosystems. For example, the racemization of amino acids can be used as a tool for dating ancient biological materials, providing insights into past life on Earth. Scientists can analyze the ratio of enantiomers in fossilized remains to estimate the age of the sample, thus contributing to our understanding of evolutionary processes.In conclusion, racemization is a fundamental process with wide-ranging implications across various fields, including chemistry, pharmacology, food science, and environmental science. As we continue to explore the complexities of chiral molecules and their interactions, a deeper understanding of racemization will undoubtedly enhance our ability to develop effective drugs, produce high-quality food, and preserve our natural environment. By studying racemization, researchers can unlock new possibilities and address challenges that arise in both scientific research and practical applications. Therefore, it is essential for students and professionals in related fields to grasp the concept of racemization and its significance in their work.
racemization是一个在化学领域中扮演重要角色的过程,尤其是在手性分子的研究中。手性分子是指存在两种互为镜像的形式的化合物,称为对映体。这些对映体可能具有非常不同的生物活性,因此理解像racemization这样的过程对于药物开发和其他应用至关重要。racemization指的是一种对映体转化为另一种对映体的过程,导致两种形式的混合。这一过程可以自然发生,也可以通过温度、pH值或催化剂的存在等各种因素诱导。在制药行业中,racemization会显著影响药物的有效性和安全性。例如,药物的一种对映体可能具有治疗活性,而另一种可能无效甚至有害。这些对映体在储存或代谢过程中发生racemization可能导致意想不到的副作用或降低药物的有效性。因此,了解促进racemization的条件对于化学家和药理学家至关重要。此外,racemization不仅在制药领域重要,在食品行业也同样如此。一些风味和香气来自手性化合物,它们的racemization可能改变食品产品的感官特性。例如,某些水果的风味特征可能由于在成熟或加工过程中某些化合物的racemization而发生变化。这突显了在食品生产中控制racemization的重要性,以确保产品的一致质量和口感。而且,racemization在环境科学中也有影响。在自然界中,许多天然产物经历racemization,这可能影响这些化合物在生态系统中的行为和命运。例如,氨基酸的racemization可作为古生物材料定年的工具,为我们提供关于地球上过去生命的见解。科学家可以分析化石遗骸中对映体的比例,以估算样本的年龄,从而有助于我们理解进化过程。总之,racemization是一个基本过程,在化学、药理学、食品科学和环境科学等多个领域具有广泛的影响。随着我们继续探索手性分子及其相互作用的复杂性,对racemization的更深入理解无疑将增强我们开发有效药物、生产高质量食品和保护自然环境的能力。通过研究racemization,研究人员可以解锁新的可能性并解决科学研究和实际应用中出现的挑战。因此,对于相关领域的学生和专业人士来说,掌握racemization的概念及其在工作中的重要性是至关重要的。