constitutively

简明释义

英[ˌkɒn.stɪˈtjuː.tɪv.li]美[ˌkɑːn.stɪˈtjuː.tɪv.li]

构成的

章程的

本质的

基本的

英英释义

单词用法

同义词

反义词

例句

1.HSP90 as a important member of HSP protein family, are usually constitutively expressed in most mammalian cell types and can be further induced by heat shock and other stresses.

HSP90是热激蛋白家族(hsp)的主要成员之一，它在细胞中呈高组成性表达，热激和其它应激条件可进一步诱导其表达。

2.Housekeeping genes are constitutively expressed genes across different tissue types to maintain the essential cellular functions.

看家基因是那些在不同的组织细胞里持续表达以维持细胞基本功能的基因。

3.Macrophages constitutively synthesize LPL, which may contribute to lipid accumulation within the arterial wall, promoting the atherogenic process.

血管壁中巨噬细胞产生脂蛋白脂酶，使脂质积聚于动脉壁内，促进动脉粥样硬化进展。

4.As with the philosophy of law, so with the philosophy of art, coming to understand these concepts is an important contribution to the life of the practices in which they figure, often constitutively.

说到法律哲学，艺术哲学也是一样，着手理解这些概念，是对这些概念在其中扮演角色(常常是本质而必要的角色)的那些实践生活的一个重要的贡献。

5.HSP90 is an important member of HSP protein family. HSP90 usually constitutively expressed in most mammalian cell types and can be further induced by heat shock and other stresses.

HSP90是热激蛋白家族(hsp)的主要成员之一，它在细胞中呈高组成性表达，热激和其他应激条件可以进一步诱导其表达。

6.Defensins are either constitutively produced or induced by bacteria and inflammatory mediators.

防御素或组成性表达或被细菌和炎症介质所诱导。

7.As with the philosophy of law, so with the philosophy of art, coming to understand these concepts is an important contribution to the life of the practices in which they figure, often constitutively.

说到法律哲学，艺术哲学也是一样，着手理解这些概念，是对这些概念在其中扮演角色(常常是本质而必要的角色)的那些实践生活的一个重要的贡献。

8.Now it has being shown that they are constitutively expressed on many tissues and or gans which enjoy immune privilege.

现已发现它们在包括眼部在内的多处免疫赦免部位都有基础性表达。

9.The protein was found to be constitutively present in all tested tissues, indicating its fundamental role in metabolism.

该蛋白在所有测试的组织中均持续性地存在，表明其在代谢中的基本作用。

10.In cancer cells, certain oncogenes are often constitutively activated, leading to uncontrolled cell growth.

在癌细胞中，某些癌基因通常是持续性地激活的，导致细胞生长失控。

11.Researchers discovered that the receptor was constitutively expressed on the surface of immune cells.

研究人员发现该受体在免疫细胞表面持续性地表达。

12.The gene is expressed constitutively, meaning it is always active regardless of environmental conditions.

这个基因是持续性地表达的，这意味着它在任何环境条件下都是活跃的。

13.Some enzymes are constitutively active and do not require additional signals for activation.

一些酶是持续性地活跃的，不需要额外的信号来激活。

作文

In the realm of molecular biology, the term constitutively refers to the persistent expression of a gene or protein under normal physiological conditions. This concept is crucial for understanding how certain proteins function continuously within a cell without the need for external stimuli. For instance, some enzymes are produced constitutively, allowing them to be readily available for metabolic processes at any given time. This continuous production ensures that the cell can respond promptly to its needs, maintaining homeostasis and overall cellular health. One classic example of constitutively expressed genes is those involved in the glycolytic pathway, which is essential for energy production. These genes are always active because cells require a constant supply of energy to perform basic functions. Without constitutively active enzymes, cells would not be able to efficiently convert glucose into ATP, the energy currency of the cell. Moreover, the study of constitutively active proteins has significant implications in the field of cancer research. Many cancer cells exhibit constitutive activation of certain signaling pathways that promote uncontrolled growth and proliferation. Understanding these mechanisms allows scientists to develop targeted therapies that can inhibit these constitutively active pathways, potentially leading to more effective treatments for cancer patients. The concept of constitutive expression also extends beyond individual genes to entire biological systems. For example, the immune system relies on constitutively active components, such as certain cytokines and receptors, to maintain surveillance against pathogens. These elements must be ready to act at all times to ensure a rapid response to infections. If these components were not expressed constitutively, the body would be vulnerable to various diseases. In summary, the term constitutively encompasses the idea of continuous, unregulated expression of genes or proteins that are vital for the proper functioning of biological systems. From energy metabolism to immune responses and cancer biology, constitutively expressed elements play a fundamental role in maintaining life and responding to challenges. As research continues to advance, a deeper understanding of constitutive expression will undoubtedly lead to new discoveries and therapeutic strategies that could improve human health. Ultimately, the significance of constitutively expressed genes and proteins cannot be overstated. They are the backbone of cellular operations, ensuring that organisms function smoothly and adapt to their environments. By studying these elements, we gain insights into the complexities of life and the intricate networks that sustain it.

在分子生物学领域，术语constitutively指的是在正常生理条件下基因或蛋白质的持续表达。这个概念对于理解某些蛋白质如何在细胞内持续发挥作用而无需外部刺激至关重要。例如，一些酶是以constitutively的方式产生，使它们在任何给定时刻都能随时用于代谢过程。这种持续的生产确保了细胞能够迅速响应其需求，维持稳态和整体细胞健康。一个经典的例子是参与糖酵解途径的constitutively表达的基因，这对能量生产至关重要。这些基因始终处于活跃状态，因为细胞需要不断供应能量来执行基本功能。如果没有constitutively活跃的酶，细胞将无法有效地将葡萄糖转化为ATP，细胞的能量货币。此外，研究constitutively活跃蛋白质在癌症研究领域具有重要意义。许多癌细胞表现出某些信号通路的constitutive激活，促使无控制的生长和增殖。了解这些机制使科学家能够开发针对这些constitutively活跃通路的靶向疗法，从而可能导致更有效的癌症治疗。constitutive表达的概念也超越了单个基因，扩展到整个生物系统。例如，免疫系统依赖于一些constitutively活跃的成分，如某些细胞因子和受体，以维持对病原体的监视。这些元素必须随时准备行动，以确保对感染的快速反应。如果这些成分不是以constitutively的方式表达，身体将容易受到各种疾病的侵袭。总之，术语constitutively包含了基因或蛋白质的连续、无调节表达的概念，这对于生物系统的正常运作至关重要。从能量代谢到免疫反应以及癌症生物学，constitutively表达的元素在维持生命和应对挑战中发挥着基础性作用。随着研究的不断推进，对constitutive表达的更深入理解无疑将带来新的发现和治疗策略，从而改善人类健康。最终，constitutively表达的基因和蛋白质的重要性不容低估。它们是细胞操作的支柱，确保生物体顺利运行并适应环境。通过研究这些元素，我们获得了对生命复杂性和维持生命的复杂网络的深入见解。