presynaptically

简明释义

英[prɪˈsɪnæptɪkli]美[prɪˈsɪnæptɪkli]

突触前的

英英释义

单词用法

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反义词

例句

1.For example, there is general agreement that cannabinoids suppress dopamine release and presynaptically reduce transmitter release from cones and bipolar cells.

例如，人们普遍认为，内源性大麻素抑制多巴胺的释放和减少锥细胞和双极细胞释放突触前递质。

2.For example, there is general agreement that cannabinoids suppress dopamine release and presynaptically reduce transmitter release from cones and bipolar cells.

例如，人们普遍认为，内源性大麻素抑制多巴胺的释放和减少锥细胞和双极细胞释放突触前递质。

3.Drugs that act presynaptically 突触前地 can enhance or inhibit neurotransmitter release.

作用于突触前地的药物可以增强或抑制神经递质的释放。

4.The study focused on how calcium channels function presynaptically 突触前地 during neurotransmitter release.

研究集中在钙通道在突触前地神经递质释放期间的功能。

5.Certain receptors are located presynaptically 突触前地, influencing the amount of neurotransmitter released.

某些受体位于突触前地，影响神经递质的释放量。

6.The neurotransmitter is released presynaptically 突触前地 to initiate the signal transmission.

神经递质在突触前地释放，以启动信号传递。

7.Inhibitory signals can act presynaptically 突触前地 to decrease neurotransmitter release.

抑制信号可以在突触前地作用以减少神经递质的释放。

作文

In the intricate world of neuroscience, understanding how neurons communicate is essential for grasping the complexities of the brain. One of the key aspects of this communication occurs at the synapse, where two neurons meet and transmit signals. The term presynaptically refers to the processes that happen before the signal is transmitted across the synaptic cleft, specifically in the neuron that sends the signal. This is a crucial phase in synaptic transmission, as it determines how effectively information is relayed from one neuron to another.When a neuron receives an action potential, it triggers the release of neurotransmitters from vesicles stored in the presynaptic terminal. These neurotransmitters are chemical messengers that travel across the synaptic cleft to bind with receptors on the postsynaptic neuron. Understanding the mechanisms that operate presynaptically can provide insights into how various factors, such as drugs or diseases, can alter neural communication.For instance, certain medications used to treat mental health disorders target the presynaptic mechanisms to enhance the release of neurotransmitters like serotonin or dopamine. By increasing the availability of these chemicals, the medications aim to improve mood and cognitive function. This highlights the importance of presynaptic activity in regulating emotions and behaviors.Moreover, research into neurodegenerative diseases has shown that dysfunction in presynaptic processes can lead to significant cognitive decline. For example, in conditions like Alzheimer's disease, the loss of presynaptic terminals contributes to the disruption of neurotransmitter signaling, which affects memory and learning. Understanding these presynaptic changes is crucial for developing effective treatments and interventions.Furthermore, the study of presynaptic mechanisms extends beyond human health; it also plays a vital role in understanding animal behavior and evolutionary biology. Different species exhibit varied presynaptic adaptations that influence their survival strategies. For example, some animals may have enhanced presynaptic release of certain neurotransmitters that facilitate quicker reflexes, providing them with a survival advantage in the wild.In conclusion, the term presynaptically encapsulates a fundamental aspect of neuronal communication that is critical for both normal brain function and the understanding of various neurological conditions. By exploring the presynaptic processes, researchers can uncover new pathways for treatment and gain a deeper appreciation for the complexities of the nervous system. As we continue to advance our knowledge in neuroscience, the significance of presynaptically mediated events will undoubtedly remain a focal point in unraveling the mysteries of the brain.

在神经科学的复杂世界中，理解神经元如何沟通对于掌握大脑的复杂性至关重要。这种沟通的一个关键方面发生在突触处，即两个神经元相遇并传递信号。术语presynaptically指的是在信号跨越突触间隙之前发生的过程，特别是在发送信号的神经元中。这是突触传输中的一个关键阶段，因为它决定了信息从一个神经元到另一个神经元的有效传递。当一个神经元接收到动作电位时，它会触发储存在突触前末端囊泡中的神经递质释放。这些神经递质是化学信使，穿过突触间隙与突触后神经元上的受体结合。理解在presynaptically运作的机制可以提供洞察，以了解各种因素（如药物或疾病）如何改变神经沟通。例如，某些用于治疗心理健康障碍的药物针对presynaptic机制，以增强神经递质如血清素或多巴胺的释放。通过增加这些化学物质的可用性，这些药物旨在改善情绪和认知功能。这突显了presynaptic活动在调节情绪和行为中的重要性。此外，对神经退行性疾病的研究表明，presynaptic过程的功能障碍可能导致显著的认知下降。例如，在阿尔茨海默病等疾病中，突触前末端的丧失导致神经递质信号传递的中断，影响记忆和学习。理解这些presynaptic变化对于开发有效的治疗和干预措施至关重要。此外，presynaptic机制的研究不仅限于人类健康；它在理解动物行为和进化生物学中也扮演着重要角色。不同物种表现出不同的presynaptic适应性，这影响它们的生存策略。例如，一些动物可能具有增强的presynaptic神经递质释放，使其反射更加迅速，从而在野外获得生存优势。总之，术语presynaptically概括了神经沟通的一个基本方面，这对正常的大脑功能和对各种神经疾病的理解至关重要。通过探索presynaptic过程，研究人员可以发现新的治疗途径，并对神经系统的复杂性有更深入的理解。随着我们在神经科学领域的不断进步，presynaptically介导事件的重要性无疑将继续成为揭示大脑奥秘的焦点。