tubocurarine

简明释义

英[ˌtjuːboʊkjuˈrɛrɪn]美[ˌtjuːboʊkjuˈrɛrɪn]

n. 筒箭毒碱

英英释义

单词用法

同义词

反义词

例句

1.The quaternary ammonium salts of liensinine differ from d-tubocurarine by one less ether linkage in chemical structure.

莲心碱的季铵盐与箭毒块茎碱的化学结构不同，缺少一个氧醚键。

2.The quaternary ammonium salts of liensinine differ from d-tubocurarine by one less ether linkage in chemical structure.

莲心碱的季铵盐与箭毒块茎碱的化学结构不同，缺少一个氧醚键。

3.Experiments were carried out on rabbits immobilized with tubocurarine under artificial respiration.

实验在筒箭毒制动和人工呼吸维持下的清醒家兔上进行。

4.Some patients may experience allergic reactions to tubocurarine 图布库拉林, requiring careful monitoring during its use.

一些患者可能对tubocurarine 图布库拉林 产生过敏反应，因此在使用过程中需要仔细监测。

5.During surgery, the anesthesiologist administered tubocurarine 图布库拉林 to facilitate intubation.

在手术期间，麻醉师给予tubocurarine 图布库拉林 以便于插管。

6.The mechanism of action of tubocurarine 图布库拉林 involves blocking acetylcholine receptors at the neuromuscular junction.

tubocurarine 图布库拉林 的作用机制涉及阻断神经肌肉接头处的乙酰胆碱受体。

7.In clinical trials, tubocurarine 图布库拉林 was compared with other neuromuscular blockers for efficacy and safety.

在临床试验中，tubocurarine 图布库拉林 与其他神经肌肉阻滞剂进行了疗效和安全性的比较。

8.In the study of neuromuscular blockers, researchers often investigate the effects of tubocurarine 图布库拉林 on muscle relaxation.

在神经肌肉阻滞剂的研究中，研究人员通常会调查tubocurarine 图布库拉林 对肌肉放松的影响。

作文

The world of medicine and pharmacology is filled with various compounds that have played significant roles in the development of anesthetics and muscle relaxants. One such compound is tubocurarine, a substance derived from the bark of certain plants in South America. Historically, tubocurarine has been used by indigenous tribes for hunting, as it can cause paralysis in animals when introduced into their bloodstream through poisoned darts. This fascinating compound has not only shaped traditional practices but has also found its way into modern medicine, particularly in the field of anesthesia.In the context of surgery, muscle relaxation is often necessary to facilitate procedures that would otherwise be impossible or extremely challenging. tubocurarine acts as a neuromuscular blocking agent, which means it interferes with the transmission of nerve impulses to muscles. By binding to the nicotinic receptors at the neuromuscular junction, tubocurarine prevents acetylcholine from triggering muscle contractions. This results in temporary paralysis, allowing surgeons to operate without the natural movements of the patient interfering with their work.The discovery and application of tubocurarine in clinical settings marked a significant advancement in surgical techniques. Before its use, surgeries were often risky due to the inability to control muscle movement effectively. With the introduction of tubocurarine, anesthesiologists gained a powerful tool that not only improved surgical outcomes but also enhanced patient safety. However, it is important to note that while tubocurarine is effective, its administration requires careful monitoring and dosage adjustments. Overdosing can lead to severe respiratory complications, as the diaphragm, the primary muscle involved in breathing, can become paralyzed.As research progressed, alternatives to tubocurarine were developed, leading to the creation of newer neuromuscular blockers with fewer side effects and shorter durations of action. These advancements have made anesthesia safer and more efficient, but the historical significance of tubocurarine cannot be overlooked. It laid the groundwork for understanding muscle relaxants and paved the way for innovations in surgical practices.Moreover, the study of tubocurarine and its mechanisms has contributed to our broader understanding of neuromuscular transmission. It has opened avenues for research into other conditions involving muscle function and nerve signaling, showcasing the interconnectedness of various fields within medicine. For instance, the knowledge gained from studying tubocurarine has implications for treating neuromuscular disorders, where similar pathways may be affected.In conclusion, tubocurarine is more than just a compound; it represents a pivotal moment in medical history that transformed surgical practices. Its journey from traditional hunting practices to modern medicine highlights the importance of understanding natural substances and their potential applications. As we continue to explore the vast realm of pharmacology, tubocurarine serves as a reminder of the delicate balance between nature and science, and the profound impact that one compound can have on the world of medicine.

医学和药理学的世界充满了各种化合物，这些化合物在麻醉剂和肌肉松弛剂的发展中发挥了重要作用。其中一种化合物是tubocurarine，它是从南美某些植物的树皮中提取的。历史上，tubocurarine被土著部落用于狩猎，因为它可以通过毒箭引入动物的血液中导致瘫痪。这种迷人的化合物不仅塑造了传统实践，还找到了进入现代医学的途径，特别是在麻醉领域。在手术的背景下，通常需要肌肉放松，以便进行否则不可能或极具挑战性的手术。tubocurarine作为一种神经肌肉阻滞剂，意味着它干扰神经冲动向肌肉的传递。通过结合在神经肌肉接头处的尼古丁受体，tubocurarine阻止乙酰胆碱触发肌肉收缩。这导致暂时性瘫痪，使外科医生能够在没有患者自然运动干扰的情况下进行手术。tubocurarine在临床环境中的发现和应用标志着外科技术的重大进步。在其使用之前，由于无法有效控制肌肉运动，手术往往风险很高。随着tubocurarine的引入，麻醉师获得了一种强大的工具，不仅改善了手术结果，还增强了患者安全性。然而，需要注意的是，虽然tubocurarine有效，但其给药需要仔细监测和剂量调整。过量使用可能导致严重的呼吸并发症，因为膈肌，即参与呼吸的主要肌肉，可能会变得瘫痪。随着研究的进展，开发了tubocurarine的替代品，导致新型神经肌肉阻滞剂的产生，这些药物具有更少的副作用和更短的作用持续时间。这些进展使麻醉更加安全和高效，但tubocurarine的历史意义不容忽视。它为理解肌肉松弛剂奠定了基础，并为外科实践的创新铺平了道路。此外，对tubocurarine及其机制的研究为我们对神经肌肉传递的更广泛理解做出了贡献。它为研究涉及肌肉功能和神经信号传递的其他疾病开辟了途径，展示了医学各个领域之间的相互关联。例如，从研究tubocurarine中获得的知识对治疗神经肌肉疾病有重要意义，因为类似的通路可能受到影响。总之，tubocurarine不仅仅是一种化合物；它代表了医学历史上的一个关键时刻，改变了外科实践。它从传统狩猎实践到现代医学的旅程突显了理解自然物质及其潜在应用的重要性。当我们继续探索药理学的广阔领域时，tubocurarine提醒我们自然与科学之间的微妙平衡，以及一种化合物对医学世界的深远影响。