noradrenergic
简明释义
英[nɔːˌædrəˈnɜːdʒɪk]美[ˌnɔrædrəˈnərdʒɪk]
adj. 去甲肾上腺素激活的;产生去甲肾上腺素的
英英释义
Relating to or denoting the neurotransmitter norepinephrine (noradrenaline) and its associated pathways in the nervous system. | 与神经递质去甲肾上腺素(去肾上腺素)及其在神经系统中的相关通路有关的。 |
单词用法
去甲肾上腺素活性 | |
去甲肾上腺素通路 | |
去甲肾上腺素信号传导 | |
去甲肾上腺素调节 | |
去甲肾上腺素功能障碍 | |
去甲肾上腺素传递 |
同义词
反义词
肾上腺能的 | Adrenergic receptors are involved in the fight-or-flight response. | 肾上腺能受体参与战斗或逃跑反应。 | |
胆碱能的 | Cholinergic drugs can enhance memory and cognitive function. | 胆碱能药物可以增强记忆和认知功能。 |
例句
1.Conclusion Dysfunction or imbalance between noradrenergic and dopaminergic neurotransmitter systems might play an leading role in the pathophysiological mechanism of ADHD.
结论adhd可能是多巴胺能和去甲肾上腺素能两种递质系统失调或失衡的结果。
2.OBJECTIVE: To study the effects of impairing the central noradrenergic system on rat's P3 like cognitive potential.
目的:研究中枢去甲肾上腺素能系统损伤对大鼠行为及认知电位类P3的影响。
3.Conclusion Dysfunction or imbalance between noradrenergic and dopaminergic neurotransmitter systems might play an leading role in the pathophysiological mechanism of ADHD.
结论adhd可能是多巴胺能和去甲肾上腺素能两种递质系统失调或失衡的结果。
4.The effect of the central noradrenergic nerve on the intracerebral vessels and local cerebral circulation was discussed.
讨论了中枢去甲肾上腺素能神经对脑实质内血管以及局部脑循环的作用。
5.The drug targets the noradrenergic 去甲肾上腺素能的 system to improve mood in patients with depression.
该药物针对noradrenergic 去甲肾上腺素能的 系统,以改善抑郁症患者的情绪。
6.Research indicates that noradrenergic 去甲肾上腺素能的 neurons play a crucial role in stress responses.
研究表明,noradrenergic 去甲肾上腺素能的 神经元在压力反应中起着关键作用。
7.An imbalance in the noradrenergic 去甲肾上腺素能的 system may contribute to anxiety disorders.
去甲肾上腺素能的系统失衡可能会导致焦虑障碍。
8.Increased noradrenergic 去甲肾上腺素能的 activity can lead to heightened alertness and focus.
增加的noradrenergic 去甲肾上腺素能的 活动可能导致警觉性和专注力的提高。
9.The noradrenergic 去甲肾上腺素能的 pathways are involved in regulating sleep-wake cycles.
noradrenergic 去甲肾上腺素能的 通路参与调节睡眠-觉醒周期。
作文
The human brain is a complex organ, responsible for numerous functions that govern our daily lives. Among the various neurotransmitters and systems that play a crucial role in brain function, the noradrenergic system stands out due to its significant influence on mood, attention, and stress responses. The term 'noradrenergic' refers to the pathways and neurons that utilize norepinephrine (also known as noradrenaline) as a neurotransmitter. This system is primarily involved in the regulation of arousal and alertness, making it essential for our ability to respond to environmental stimuli.Understanding the noradrenergic system begins with recognizing the role of norepinephrine in the body. Norepinephrine is produced in the locus coeruleus, a small nucleus in the brainstem, and is released throughout various regions of the brain and body. It affects numerous physiological processes, including heart rate, blood pressure, and the fight-or-flight response. When faced with a stressful situation, the noradrenergic system activates, leading to increased alertness and readiness to react. This response is vital for survival, as it prepares the body to face potential threats.In addition to its role in stress responses, the noradrenergic system also plays a critical part in regulating mood and emotional states. Research has shown that alterations in norepinephrine levels can contribute to mood disorders such as depression and anxiety. For instance, many antidepressant medications aim to enhance the noradrenergic system's activity, thereby improving mood and alleviating symptoms of depression. By increasing the availability of norepinephrine in the synaptic cleft, these medications help restore balance in the brain's neurotransmitter systems.Moreover, the noradrenergic system is closely linked to attention and cognitive function. Studies have indicated that norepinephrine enhances signal detection and improves focus, particularly in challenging situations. This connection is especially relevant in conditions like Attention Deficit Hyperactivity Disorder (ADHD), where deficits in norepinephrine signaling may contribute to difficulties in maintaining attention. Medications that target the noradrenergic system, such as certain stimulants, have been found effective in managing symptoms of ADHD by promoting better concentration and reducing impulsivity.Interestingly, the noradrenergic system does not operate in isolation; it interacts with other neurotransmitter systems, including the serotonergic and dopaminergic systems. This interconnectedness highlights the complexity of brain function and the need for a holistic understanding of how different systems work together. For example, while norepinephrine may enhance alertness, serotonin is often associated with feelings of well-being and happiness. A delicate balance between these neurotransmitters is crucial for maintaining mental health and overall well-being.In conclusion, the noradrenergic system plays a pivotal role in various aspects of human behavior and physiology. From regulating stress responses to influencing mood and attention, norepinephrine is a key player in the intricate network of neurotransmitters that govern our daily experiences. As research continues to uncover the complexities of the brain, understanding the noradrenergic system will remain vital for developing effective treatments for mood disorders, attention deficits, and other related conditions. By appreciating the significance of this system, we can gain deeper insights into the mechanisms underlying human behavior and the potential for therapeutic interventions.
人脑是一个复杂的器官,负责许多影响我们日常生活的功能。在影响大脑功能的各种神经递质和系统中,去甲肾上腺素能系统因其对情绪、注意力和压力反应的重要影响而脱颖而出。术语“去甲肾上腺素能”指的是利用去甲肾上腺素(也称为去肾上腺素)作为神经递质的通路和神经元。该系统主要参与觉醒和警觉性的调节,使其对我们应对环境刺激的能力至关重要。理解去甲肾上腺素能系统始于认识去甲肾上腺素在身体中的作用。去甲肾上腺素在脑干的小核团——蓝斑中产生,并释放到大脑和身体的各个区域。它影响许多生理过程,包括心率、血压和战斗或逃跑反应。当面临压力情况时,去甲肾上腺素能系统会激活,从而提高警觉性并准备反应。这种反应对生存至关重要,因为它使身体准备面对潜在威胁。除了在压力反应中的作用外,去甲肾上腺素能系统还在调节情绪和情感状态方面发挥着关键作用。研究表明,去甲肾上腺素水平的变化可能导致抑郁和焦虑等情绪障碍。例如,许多抗抑郁药物旨在增强去甲肾上腺素能系统的活动,从而改善情绪并减轻抑郁症状。通过增加突触间隙中去甲肾上腺素的可用性,这些药物有助于恢复大脑神经递质系统的平衡。此外,去甲肾上腺素能系统与注意力和认知功能密切相关。研究表明,去甲肾上腺素可以增强信号检测并改善专注力,尤其是在具有挑战性的情况下。这种联系在注意缺陷多动障碍(ADHD)等疾病中尤为相关,其中去甲肾上腺素信号传导的缺陷可能导致维持注意力的困难。针对去甲肾上腺素能系统的药物,例如某些兴奋剂,已被发现有效地管理ADHD的症状,通过促进更好的集中注意力和减少冲动行为。有趣的是,去甲肾上腺素能系统并不是孤立运作的;它与其他神经递质系统(包括5-羟色胺能和多巴胺能系统)相互作用。这种相互联系凸显了大脑功能的复杂性,以及对不同系统如何协同工作的整体理解的需求。例如,虽然去甲肾上腺素可能增强警觉性,但5-羟色胺通常与幸福感和愉悦感相关。这些神经递质之间的微妙平衡对于维持心理健康和整体福祉至关重要。总之,去甲肾上腺素能系统在人类行为和生理的各个方面发挥着关键作用。从调节压力反应到影响情绪和注意力,去甲肾上腺素是支配我们日常体验的错综复杂的神经递质网络中的关键角色。随着研究不断揭示大脑的复杂性,理解去甲肾上腺素能系统将对开发有效的情绪障碍、注意力缺陷及其他相关疾病的治疗方法至关重要。通过欣赏这一系统的重要性,我们可以更深入地了解支配人类行为的机制以及治疗干预的潜力。