valproate

简明释义

英[vælˈprəʊeɪt]美[vælˈproʊeɪt]

n. 2-丙基戊酸钠（抗惊厥药，能防止轻度癫痫发作）

英英释义

单词用法

同义词

反义词

例句

1.Methods: Seizures in the group of epileptic rats induced by penicillin, the group of the LTG, and the group of the sodium valproate were measured, and the EEG was recorded for the groups.

方法：观察青霉素致痫组、拉莫三嗪组、丙戊酸钠组大鼠痫性发作，并记录其脑电图。

2.There were no significant differences between the levetiracetam and valproate groups.

左乙拉西坦组与丙戊酸钠组差异无统计学意义。

3.Objective To observe the effect of magnesium valproate sustained release tablets on children with epilepsy and its effects on cognitive function.

目的观察丙戊酸镁缓释剂治疗癫的疗效及其对癫患儿认知功能的影响。

4.METHODS: the serum concentrations of valproate in 276 patients were determined by fluorescence polarization immunoassay and the results were analyzed.

方法：采用荧光偏振免疫法测定276例癫痫患者的丙戊酸血药浓度并分析结果。

5.CONCLUSION: in therapeutic drug monitoring of valproate, it should be concerned about the impact factors of valproate concentration to ensure the safety and efficacy in patients.

结论：在丙戊酸治疗药物监测中，要关注影响丙戊酸血药浓度的因素，确保患者用药安全有效。

6.Objective: to evaluate the efficacy and side effects of sodium valproate and carbamazepine in the treatment of manic episodes refractory to lithium carbonate.

目的：评价丙戊酸钠与卡马西平对锂盐治疗无效的躁狂发作的疗效和副反应。

7.Valproate acid had no influence on fasting serum insulin level of epileptic patients, but can increase their fasting serum leptin level, especially obese epileptic patients.

丙戊酸对癫痫病人空腹胰岛素水平无明显影响；可显著增加癫痫病人的空腹瘦素水平，尤其是肥胖病人。

8.Objective To investigate the clinical efficacy and side effects of sodium valproate in the treatment of alcohol withdrawal reaction.

目的探讨丙戊酸钠对酒精戒断反应的临床疗效及副反应。

9.Before starting valproate, the patient underwent a series of tests to ensure it was safe.

在开始服用丙戊酸钠之前，患者接受了一系列测试以确保安全。

10.The doctor prescribed valproate for her epilepsy, which is a common treatment option.

医生为她开了丙戊酸钠，这是治疗癫痫的常见选择。

11.It is important to monitor liver function while on valproate therapy.

在接受丙戊酸钠治疗时，监测肝功能非常重要。

12.Valproate can also be used to treat bipolar disorder in some patients.

丙戊酸钠也可以用于治疗某些患者的双相情感障碍。

13.Some patients may experience side effects when taking valproate, such as drowsiness or nausea.

一些患者在服用丙戊酸钠时可能会出现副作用，如嗜睡或恶心。

作文

Valproate, a medication primarily used to treat epilepsy and bipolar disorder, has become a significant topic in the field of psychiatry and neurology. This compound, known for its anticonvulsant properties, works by increasing the levels of gamma-aminobutyric acid (GABA) in the brain, which helps to stabilize mood and prevent seizures. As a result, many individuals suffering from these conditions rely on valproate (丙戊酸钠) to manage their symptoms effectively.The history of valproate (丙戊酸钠) dates back to the 1960s when it was first introduced as a treatment for epilepsy. Over the years, its use has expanded to include various psychiatric disorders, particularly bipolar disorder. Patients with bipolar disorder often experience extreme mood swings, and the stabilization offered by valproate (丙戊酸钠) can be life-changing. The medication helps to mitigate the manic episodes that can lead to impulsive behavior and severe consequences.However, like any medication, valproate (丙戊酸钠) is not without its side effects. Common adverse effects include gastrointestinal disturbances, weight gain, and hair loss. More serious risks involve liver damage and pancreatitis, making it essential for healthcare providers to monitor patients closely while they are on this medication. Despite these potential issues, the benefits often outweigh the risks for many patients, allowing them to lead more stable and fulfilling lives.Research continues to explore the full range of effects that valproate (丙戊酸钠) can have on the brain and body. Studies have indicated that it may also possess neuroprotective properties, which could be beneficial in treating other neurological conditions such as Alzheimer's disease and multiple sclerosis. This expanding research base highlights the importance of valproate (丙戊酸钠) not only as a treatment for epilepsy and bipolar disorder but also as a potential therapeutic agent in other areas of medicine.In addition to its clinical applications, the discussion surrounding valproate (丙戊酸钠) also touches on ethical considerations. For instance, the use of this medication during pregnancy raises concerns due to potential teratogenic effects. Pregnant women who take valproate (丙戊酸钠) face a higher risk of giving birth to children with developmental disorders. Thus, it is crucial for healthcare providers to weigh the benefits against the risks and consider alternative treatments when necessary.In conclusion, valproate (丙戊酸钠) is a powerful medication that plays a vital role in managing epilepsy and bipolar disorder. Its ability to enhance GABA levels in the brain allows individuals to achieve better control over their conditions. While there are side effects and ethical considerations to keep in mind, ongoing research continues to uncover the potential of valproate (丙戊酸钠) as a multifaceted treatment option. For those affected by epilepsy and bipolar disorder, valproate (丙戊酸钠) remains an essential part of their journey toward stability and health.

丙戊酸钠是一种主要用于治疗癫痫和双相情感障碍的药物，在精神病学和神经学领域成为了一个重要的话题。这种化合物以其抗惊厥特性而闻名，它通过增加大脑中γ-氨基丁酸（GABA）的水平来发挥作用，这有助于稳定情绪并防止癫痫发作。因此，许多患有这些疾病的个体依赖于valproate（丙戊酸钠）来有效管理他们的症状。valproate（丙戊酸钠）的历史可以追溯到20世纪60年代，当时它首次被引入用于治疗癫痫。多年来，其用途扩大到包括各种精神疾病，尤其是双相情感障碍。双相情感障碍患者常常经历极端的情绪波动，而valproate（丙戊酸钠）提供的稳定性可以改变生活。这种药物有助于缓解可能导致冲动行为和严重后果的躁狂发作。然而，像任何药物一样，valproate（丙戊酸钠）也不是没有副作用。常见的不良反应包括胃肠道不适、体重增加和脱发。更严重的风险涉及肝损伤和胰腺炎，因此医疗保健提供者在患者服用该药物期间必须密切监测。尽管存在这些潜在问题，但对许多患者来说，益处往往超过风险，使他们能够过上更稳定和充实的生活。研究还在继续探索valproate（丙戊酸钠）对大脑和身体的全部影响范围。研究表明，它可能还具有神经保护特性，这对于治疗其他神经系统疾病，如阿尔茨海默病和多发性硬化症，可能是有益的。这一不断扩展的研究基础突显了valproate（丙戊酸钠）不仅作为癫痫和双相情感障碍的治疗手段的重要性，也作为其他医学领域潜在治疗剂的重要性。除了临床应用外，围绕valproate（丙戊酸钠）的讨论还涉及伦理考虑。例如，怀孕期间使用这种药物会引发担忧，因为可能存在致畸作用。服用valproate（丙戊酸钠）的孕妇面临生育发育障碍儿童的风险更高。因此，医疗保健提供者在必要时必须权衡益处与风险，并考虑替代治疗方案。总之，valproate（丙戊酸钠）是一种强效药物，在管理癫痫和双相情感障碍方面发挥着至关重要的作用。它提高大脑中GABA水平的能力使个体能够更好地控制他们的病情。尽管需要考虑副作用和伦理问题，但持续的研究仍在不断揭示valproate（丙戊酸钠）作为多功能治疗选择的潜力。对于那些受到癫痫和双相情感障碍影响的人来说，valproate（丙戊酸钠）仍然是他们通向稳定和健康之旅的重要组成部分。