heterozygosity

简明释义

英[ˌhetərəʊzaɪˈɡɒsɪti]美[hetəroʊzaɪˈɡɑːsəti]

n. [遗] 杂合性；异型接合性

英英释义

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例句

1.Objective: To investigate the loss of heterozygosity (LOH) of ATM gene and BRCA2 gene and explore the relationship between two genes in patients with ALL and ANLL.

目的：探讨急性淋巴细胞白血病(all)与急性非淋巴细胞白血病(ANLL)AT M基因和BRCA2基因杂合性缺失及其相互关系。

2.Selfing heterozygotes halves the heterozygosity, and thus outbreeding maintains heterozygosity and produces a more adaptable population.

自交杂合子有一半杂合性，因此远系繁殖可以产生适应能量更强的种群。

3.The average heterozygosity of 13 protein loci was highest in pigmented guinea pig(0.350 1), followed by WHBE guinea pig(0.339 0) and DHP guinea pig(0.313 5).

在三个豚鼠品种中，所检测的13个蛋白位点的平均杂合度的排列顺序为：花色豚鼠（0.3501）〉WHBE豚鼠（0.339 0）〉DHP豚鼠（0.313 5）。

4.AIM: To examine the microsatellite instability (MSI) and loss of heterozygosity (LOH) in head and neck squamous cell carcinomas (HNSCC).

目的：探讨头颈部鳞癌的微卫星不稳定性(msi)及杂合性丢失(LOH)。

5.The gene heterozygosity, the gene homogeneity index and the number of effective allele were 0.0718, 0.8564 and 1.0774, resp.

高原型牦牛红细胞钾浓度基因座的基因杂合度、基因纯合度指数和有效等位基因数分别为0 0718,0 8564和1 0774。

6.The gene heterozygosity was 0. 5520 on the locus of serum esterase. The gene differentiation coefficient among populations was very small (0. 33 %).

血清酯酶基因座的基因杂合度为0.5520，群体间基因分化系数很小(0.33%)。

7.Researchers measured the heterozygosity 杂合性 of various species to assess their genetic diversity.

研究人员测量了不同物种的heterozygosity 杂合性以评估它们的遗传多样性。

8.Inbreeding can lead to a decrease in heterozygosity 杂合性, which may increase the risk of genetic disorders.

近交可能导致heterozygosity 杂合性的减少，从而增加遗传疾病的风险。

9.High heterozygosity 杂合性 is often an indicator of a healthy breeding population.

高heterozygosity 杂合性通常是健康繁殖种群的指标。

10.The conservation program aimed to maintain heterozygosity 杂合性 in endangered species.

该保护计划旨在保持濒危物种的heterozygosity 杂合性。

11.The study found that increased levels of heterozygosity 杂合性 were associated with better survival rates in the population.

研究发现，增加的heterozygosity 杂合性水平与该人群的更好生存率相关。

作文

Heterozygosity is a fundamental concept in genetics that refers to the presence of different alleles at a particular gene locus on homologous chromosomes. In simpler terms, it means that an individual has inherited different forms of a gene from each parent, resulting in a pair of alleles that are not identical. The importance of heterozygosity (杂合性) cannot be overstated, as it plays a crucial role in genetic diversity and the overall health of populations.One of the most significant advantages of heterozygosity (杂合性) is that it contributes to genetic variation within a population. This variation is essential for the process of natural selection, as it provides a pool of traits that may be beneficial in changing environments. For instance, in a population of plants, those that possess alleles for drought resistance may survive better during dry periods. If all individuals were homozygous (纯合的) for the same allele, the entire population could be wiped out by a single environmental change. Therefore, heterozygosity (杂合性) enhances a population's ability to adapt and thrive under various conditions.Moreover, heterozygosity (杂合性) is also vital for maintaining the health of individuals within a species. Individuals who are heterozygous for certain genes often exhibit what's known as hybrid vigor or heterosis. This phenomenon results in enhanced growth, fertility, and overall fitness compared to their homozygous counterparts. For example, in agriculture, crossbreeding different strains of crops can lead to offspring that are more robust and yield higher produce. This principle is applied widely in animal breeding as well, where the goal is to produce animals with desirable traits through heterozygosity (杂合性).In conservation biology, understanding heterozygosity (杂合性) is critical for preserving endangered species. A loss of genetic diversity due to inbreeding can lead to a decrease in heterozygosity (杂合性), making populations more susceptible to diseases and reducing their ability to adapt to environmental changes. Conservation efforts often focus on maintaining or increasing heterozygosity (杂合性) within threatened populations to ensure their long-term survival. This can involve strategies such as habitat restoration, controlled breeding programs, and genetic monitoring.On a broader scale, heterozygosity (杂合性) has implications for human health as well. Certain genetic disorders are associated with homozygosity for harmful alleles, while being heterozygous can provide a protective effect. For instance, individuals who carry one sickle cell allele and one normal allele (heterozygous) are less likely to suffer severe consequences from malaria compared to those who are homozygous for the normal allele. This illustrates how heterozygosity (杂合性) can influence disease resistance and overall health outcomes.In conclusion, heterozygosity (杂合性) is a vital aspect of genetics that significantly impacts biodiversity, individual fitness, conservation efforts, and human health. By promoting genetic variation, heterozygosity (杂合性) enables populations to adapt to changing environments and resist diseases. Understanding this concept is essential for biologists, conservationists, and anyone interested in the mechanisms of evolution and the preservation of life on Earth. The study of heterozygosity (杂合性) continues to be a rich field of research, revealing the intricate connections between genetics and the survival of species.

杂合性是遗传学中的一个基本概念，指的是在同源染色体上的特定基因位点存在不同等位基因。简单来说，这意味着个体从每个父母那里继承了不同形式的基因，从而导致一对等位基因不相同。heterozygosity（杂合性）的重要性不容小觑，因为它在遗传多样性和种群整体健康中起着至关重要的作用。heterozygosity（杂合性）的一个显著优势是它有助于种群内的遗传变异。这种变异对于自然选择过程至关重要，因为它提供了一系列可能在变化环境中有益的特征。例如，在一群植物中，那些具有抗旱等位基因的植物在干旱时期可能生存得更好。如果所有个体在同一个等位基因上都是纯合的，那么整个种群可能会因单一的环境变化而灭绝。因此，heterozygosity（杂合性）增强了种群在各种条件下适应和繁荣的能力。此外，heterozygosity（杂合性）对于维持物种内个体的健康也至关重要。那些在某些基因上是杂合的个体往往表现出所谓的杂交优势或杂种优势。这种现象导致与其纯合的同类相比，生长、繁殖和整体适应性增强。例如，在农业中，不同品种作物的杂交可以产生更强壮、产量更高的后代。这一原则在动物育种中也被广泛应用，目标是通过heterozygosity（杂合性）生产具有理想特征的动物。在保护生物学中，理解heterozygosity（杂合性）对于保护濒危物种至关重要。由于近亲繁殖导致的遗传多样性丧失会导致heterozygosity（杂合性）的减少，使种群更容易受到疾病的影响，并降低其适应环境变化的能力。保护工作通常侧重于维持或增加濒危种群中的heterozygosity（杂合性），以确保其长期生存。这可能涉及栖息地恢复、控制繁殖计划和遗传监测等策略。在更广泛的层面上，heterozygosity（杂合性）对人类健康也有影响。某些遗传疾病与有害等位基因的纯合性相关，而杂合性可能提供保护作用。例如，携带一个镰刀型细胞等位基因和一个正常等位基因（杂合）的个体，相较于纯合正常等位基因的人，更不容易遭受疟疾的严重后果。这说明了heterozygosity（杂合性）如何影响疾病抵抗力和整体健康结果。总之，heterozygosity（杂合性）是遗传学的一个重要方面，对生物多样性、个体适应性、保护努力和人类健康有显著影响。通过促进遗传变异，heterozygosity（杂合性）使种群能够适应变化的环境并抵御疾病。理解这一概念对于生物学家、保护主义者以及任何对进化机制和生命保护感兴趣的人都至关重要。对heterozygosity（杂合性）的研究仍然是一个丰富的研究领域，揭示了遗传学与物种生存之间错综复杂的联系。