sphingomyelin

简明释义

英[ˌsfɪŋɡəʊˈmaɪəlɪn]美[ˌsfɪŋɡoʊˈmaɪəlɪn]

n. （神经）鞘磷脂

英英释义

单词用法

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反义词

例句

1.High sphingomyelin phosphodiesterase-producing Actinomucor elegans mutant(AE255-6) was obtained by radiation of CO2 laser.

用CO2激光辐射筛选培育出高产鞘磷脂酶的工程菌——雅致放射毛霉变异株AE255-6。

2.METHOD Sphingomyelin was prepared through the process of separating erythrocyte from blood, erythrocytolysis, dehydration, dry, et al, and then hydrolyzed to ceramide by phospholipase C.

方法分离猪血细胞，用溶血，脱水，干燥等方法提取鞘磷脂，并用磷脂酶C降解鞘磷脂成神经酰胺。

3.CONCLUSION Sphingomyelin can be obtained from erythrocyte membrane by this method.

结论用此法可将红细胞膜中的鞘磷脂降解成神经酰胺。

4.OBJECTIVE To extract the sphingomyelin from erythrocyte membrane and hydrolyze it to ceramide.

目的从红细胞膜中提取鞘磷脂并降解成神经酰胺。

5.METHOD Sphingomyelin was prepared through the process of separating erythrocyte from blood, erythrocytolysis, dehydration, dry, et al, and then hydrolyzed to ceramide by phospholipase C.

方法分离猪血细胞，用溶血，脱水，干燥等方法提取鞘磷脂，并用磷脂酶C降解鞘磷脂成神经酰胺。

6.High levels of sphingomyelin are associated with cardiovascular diseases.

高水平的鞘磷脂与心血管疾病相关。

7.Deficiencies in sphingomyelin can lead to serious health issues.

缺乏鞘磷脂可能导致严重的健康问题。

8.The study focused on the role of sphingomyelin in cell membrane structure.

这项研究集中于鞘磷脂在细胞膜结构中的作用。

9.Researchers are investigating the metabolism of sphingomyelin in neurological disorders.

研究人员正在调查鞘磷脂在神经系统疾病中的代谢。

10.The presence of sphingomyelin in the diet may influence brain health.

饮食中鞘磷脂的存在可能影响大脑健康。

作文

Sphingomyelin is a type of sphingolipid, which is a class of lipids that play critical roles in cellular structure and signaling. It is primarily found in the membranes of cells, especially in the myelin sheath that surrounds nerve fibers. The presence of sphingomyelin (神经酰胺) in myelin is essential for the proper conduction of electrical impulses along nerves, making it a vital component for the functioning of the nervous system. This lipid is composed of a sphingosine backbone, a fatty acid, and a phosphocholine head group, which contributes to its unique properties and functions.The significance of sphingomyelin (神经酰胺) extends beyond just its structural role. Research has shown that it is involved in various cellular processes, including cell signaling, apoptosis (programmed cell death), and the regulation of membrane fluidity. In particular, sphingomyelin (神经酰胺) can be metabolized into other bioactive lipids, such as ceramide, which has been implicated in stress responses and inflammation. This metabolic pathway highlights the importance of sphingomyelin (神经酰胺) in maintaining cellular homeostasis and responding to external stimuli.Moreover, alterations in the levels of sphingomyelin (神经酰胺) have been linked to various diseases. For instance, a decrease in sphingomyelin (神经酰胺) levels has been associated with neurodegenerative diseases such as multiple sclerosis and Alzheimer’s disease. In these conditions, the degradation of myelin leads to impaired nerve function and cognitive decline. Understanding the role of sphingomyelin (神经酰胺) in these diseases could pave the way for new therapeutic strategies aimed at restoring myelin integrity or modulating sphingolipid metabolism.In addition to its implications in health and disease, sphingomyelin (神经酰胺) also serves as a marker for certain pathological conditions. For example, elevated levels of sphingomyelin (神经酰胺) in the blood can indicate the presence of cardiovascular diseases, as it is involved in the formation of atherosclerotic plaques. Therefore, monitoring sphingomyelin (神经酰胺) levels could provide valuable insights into an individual’s risk for developing heart-related issues.In conclusion, sphingomyelin (神经酰胺) is a crucial lipid that plays an integral role in cellular functions and overall health. Its presence in cell membranes, particularly in the nervous system, underscores its importance in maintaining proper nerve function. As research continues to uncover the complexities of sphingomyelin (神经酰胺) metabolism and its implications in various diseases, it becomes increasingly clear that this lipid is not only essential for cellular structure but also a key player in signaling pathways and disease mechanisms. Future studies focusing on sphingomyelin (神经酰胺) may lead to innovative approaches in treating neurological disorders and improving cardiovascular health.

神经酰胺是一种鞘脂，是一类在细胞结构和信号传递中发挥关键作用的脂质。它主要存在于细胞膜中，尤其是在包围神经纤维的髓鞘中。sphingomyelin（神经酰胺）在髓鞘中的存在对于电信号沿神经的正确传导至关重要，使其成为神经系统功能的一个重要组成部分。这种脂质由鞘氨醇骨架、脂肪酸和磷胆碱头基组成，这赋予了它独特的性质和功能。sphingomyelin（神经酰胺）的重要性不仅仅体现在其结构角色上。研究表明，它参与多种细胞过程，包括细胞信号传递、凋亡（程序性细胞死亡）以及膜流动性的调节。特别是，sphingomyelin（神经酰胺）可以代谢为其他生物活性脂质，如神经酰胺，这与应激反应和炎症有关。这一代谢途径突显了sphingomyelin（神经酰胺）在维持细胞稳态和响应外部刺激中的重要性。此外，sphingomyelin（神经酰胺）水平的变化与多种疾病相关。例如，sphingomyelin（神经酰胺）水平的降低与多发性硬化症和阿尔茨海默病等神经退行性疾病相关。在这些情况下，髓鞘的降解导致神经功能受损和认知能力下降。理解sphingomyelin（神经酰胺）在这些疾病中的作用可能为恢复髓鞘完整性或调节鞘脂代谢的新治疗策略铺平道路。除了在健康和疾病中的意义外，sphingomyelin（神经酰胺）还作为某些病理条件的标志物。例如，血液中sphingomyelin（神经酰胺）水平升高可能表明心血管疾病的存在，因为它参与动脉粥样硬化斑块的形成。因此，监测sphingomyelin（神经酰胺）水平可能为个人发展心脏相关问题的风险提供有价值的见解。总之，sphingomyelin（神经酰胺）是一种至关重要的脂质，在细胞功能和整体健康中发挥着不可或缺的作用。它在细胞膜中的存在，尤其是在神经系统中，强调了它在维持神经功能正常方面的重要性。随着研究不断揭示sphingomyelin（神经酰胺）代谢的复杂性及其在各种疾病中的影响，越来越清楚的是，这种脂质不仅对细胞结构至关重要，而且在信号通路和疾病机制中也是一个关键角色。未来专注于sphingomyelin（神经酰胺）的研究可能会导致治疗神经系统疾病和改善心血管健康的创新方法。