phagosome

简明释义

英[ˈfæɡəʊsəm]美[fæɡəˌsoʊm]

n. （细胞中的）吞噬体

英英释义

单词用法

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例句

1.The phagosome, degenerated organelles and big vacuoles-shape with flocculent material were also observed in the cytoplasm of bone marrow cells.

偶见吞噬体，胞浆内细胞器变性及大的泡状结构，内含絮状物。

2.The phagosome, degenerated organelles and big vacuoles-shape with flocculent material were also observed in the cytoplasm of bone marrow cells.

偶见吞噬体，胞浆内细胞器变性及大的泡状结构，内含絮状物。

3.The immune cells engulf bacteria, forming a phagosome (吞噬体) that helps in digestion.

免疫细胞吞噬细菌，形成一个phagosome（吞噬体），有助于消化。

4.In the process of autophagy, cellular debris is enclosed in a phagosome (吞噬体) for degradation.

在自噬过程中，细胞碎片被包裹在一个phagosome（吞噬体）中以进行降解。

5.The formation of a phagosome (吞噬体) is crucial for the clearance of pathogens from the body.

形成phagosome（吞噬体）对清除体内病原体至关重要。

6.Research shows that the maturation of a phagosome (吞噬体) is essential for effective immune response.

研究表明，phagosome（吞噬体）的成熟对有效的免疫反应至关重要。

7.After a pathogen is engulfed, it resides within a phagosome (吞噬体) where it is exposed to digestive enzymes.

病原体被吞噬后，停留在一个phagosome（吞噬体）内，在那里它暴露于消化酶中。

作文

In the realm of cellular biology, understanding the mechanisms by which cells interact with their environment is crucial. One of the key processes in this interaction is phagocytosis, a form of endocytosis where cells engulf large particles, such as bacteria or dead cell debris. The result of this process is the formation of a structure known as a phagosome, which plays a critical role in the immune response and cellular maintenance.When a cell encounters a foreign particle, it extends its membrane around the particle, eventually enclosing it within a pocket. This pocket then pinches off from the cell membrane, forming a phagosome. The newly formed phagosome is essentially a vesicle that contains the engulfed material. Once inside the cell, the phagosome undergoes a series of transformations. It typically fuses with lysosomes, which are organelles containing digestive enzymes. This fusion forms a new structure called a phagolysosome, where the contents of the phagosome are broken down and digested.The importance of phagosomes cannot be overstated. They are essential for the innate immune system, providing a mechanism for immune cells like macrophages and neutrophils to eliminate pathogens. When these cells encounter bacteria, they utilize the phagosome formation process to engulf and destroy these invaders, thereby preventing infections and maintaining tissue health. Additionally, phagosomes also play a role in the clearance of apoptotic cells, which is vital for tissue homeostasis and regeneration.Furthermore, research has shown that the functionality of phagosomes can influence the overall immune response. For instance, the ability of a phagosome to fuse efficiently with lysosomes determines how effectively a cell can degrade pathogens. If this process is impaired, it can lead to chronic infections or autoimmune diseases, highlighting the need for further studies on phagosomes and their roles in various diseases.In addition to their role in immunity, phagosomes also have implications in cancer research. Tumor cells can exploit the phagocytic process to evade immune detection. They may manipulate the phagosome pathway to create an immunosuppressive environment, allowing them to grow unchecked. Understanding how phagosomes operate in cancerous cells could lead to novel therapeutic approaches aimed at enhancing the immune response against tumors.In conclusion, the phagosome is a vital component of cellular biology, particularly in the context of the immune system. Its formation and function are critical for the elimination of pathogens and the maintenance of cellular health. As research continues to uncover the complexities of phagosomes, we gain deeper insights into their roles not just in immunity but also in disease processes, paving the way for potential advancements in medical treatments and therapies. The study of phagosomes exemplifies the intricate dance between cells and their environment, showcasing the remarkable capabilities of our immune system in protecting and sustaining life.

在细胞生物学的领域，理解细胞与其环境相互作用的机制至关重要。细胞吞噬作用是其中一种关键过程，是一种内吞作用，细胞通过这种方式吞噬大颗粒，例如细菌或死亡细胞碎片。这个过程的结果是形成一个被称为吞噬体的结构，这在免疫反应和细胞维持中发挥着关键作用。当细胞遇到外来颗粒时，它会将膜延伸到颗粒周围，最终将其包裹在一个口袋中。这个口袋随后从细胞膜上断裂，形成一个吞噬体。新形成的吞噬体本质上是一个包含吞噬材料的囊泡。一旦进入细胞，吞噬体经历一系列转变。它通常与含有消化酶的细胞器——溶酶体融合。这种融合形成了一个新的结构，称为吞噬溶酶体，在这里，吞噬体的内容物被分解和消化。吞噬体的重要性不容低估。它们对先天免疫系统至关重要，为巨噬细胞和中性粒细胞等免疫细胞提供了一种消灭病原体的机制。当这些细胞遇到细菌时，它们利用吞噬体形成过程来吞噬和破坏这些入侵者，从而防止感染，维持组织健康。此外，吞噬体在清除凋亡细胞方面也发挥着作用，这对组织稳态和再生至关重要。此外，研究表明，吞噬体的功能性可以影响整体免疫反应。例如，吞噬体与溶酶体有效融合的能力决定了细胞消化病原体的效果。如果这一过程受损，可能导致慢性感染或自身免疫疾病，突显了对吞噬体及其在各种疾病中作用进一步研究的必要性。除了在免疫中的作用，吞噬体在癌症研究中也有影响。肿瘤细胞可以利用吞噬作用过程来逃避免疫检测。它们可能操控吞噬体通路，以创造一个免疫抑制环境，使其能够不受限制地生长。理解吞噬体在癌细胞中的运作可能导致针对增强免疫反应的新治疗方法。总之，吞噬体是细胞生物学的一个重要组成部分，特别是在免疫系统的背景下。它的形成和功能对于消除病原体和维持细胞健康至关重要。随着研究继续揭示吞噬体的复杂性，我们对它们在免疫和疾病过程中的作用有了更深入的了解，为潜在的医学治疗和疗法的进步铺平了道路。吞噬体的研究展示了细胞与其环境之间复杂的舞蹈，体现了我们免疫系统在保护和维持生命方面的卓越能力。