cyclization

简明释义

英[ˌsaɪkləˈzeɪʃən]美[ˌsaɪklɪˈzeɪʃn]

n. [化学] 环化；环合作用

英英释义

单词用法

同义词

反义词

例句

1.Cyclization occurs readily with dilute alkali.

遇到稀碱就容易环化。

2.This paper reports the improvement on the synthesis of 5 methylisoxazol 3 formamide by Claisen condensation of diethyl oxalacetate followed by cyclization and ammonolysis.

讨论了以草酸二乙酯为原料，经过克莱森缩合、环合、氨解反应合成5甲基异唑3甲酰胺工艺的改进。

3.METHODS Cilnidipine was synthesized from cinnamyl alcohol by esterification, feminization and condensation - cyclization.

方法以肉桂醇为原料，经酯化、氨化和缩合-环合而得。

4.METHODS Bretazenil was synthesized from 3-bromoaniline by cyclization, oxidation and ring-enlargement reaction, etc.

方法以3-溴苯胺为起始原料，经过成环、氧化、扩环等反应得到目标产物。

5.The mechanism of cyclization of DAT and the principle of the anion extraction were also discussed.

同时，探讨了DAT的成环反应历程，阐述了阴离子高效萃取的原理。

6.The phenomonon was explained in view of the mechanism of chemical cyclization of poly(amic acid).

从聚酰胺酸化学环化反应机理出发对这一结果给予了解释。

7.The resin (b) is preferred to be conjugated diene polymer cyclization material with unsaturated bond decrement rate more than 10%.

树脂(B)优选为不饱和键减少率为10%以上的共轭二烯聚合物环化物。

8.The method adopts the amino resin to synthesize carbetocin by the solid phase cyclization technology.

本发明采用氨基树脂，固相环合技术，合成卡贝缩宫素。

9.During the synthesis of this compound, cyclization occurs at elevated temperatures.

在合成这个化合物的过程中，环化发生在高温下。

10.In polymer chemistry, cyclization can lead to the formation of cyclic polymers.

在聚合物化学中，环化可以导致环状聚合物的形成。

11.The study focused on the mechanisms of cyclization in various natural products.

该研究集中于各种天然产物中环化的机制。

12.The cyclization reaction was crucial for the development of the new drug.

这次环化反应对新药的开发至关重要。

13.The process of forming a ring structure in organic chemistry is known as cyclization.

在有机化学中，形成环状结构的过程称为环化。

作文

Cyclization is a crucial process in organic chemistry that refers to the formation of a cyclic compound from a linear or acyclic precursor. This transformation is significant because it often leads to molecules with unique properties and reactivities that are not present in their open-chain counterparts. The concept of cyclization (环化) can be observed in various biochemical processes, synthetic pathways, and natural product formations. Understanding how cyclization (环化) occurs and its implications in different fields can enhance our grasp of molecular design and reaction mechanisms.In organic synthesis, the ability to create cyclic structures is invaluable. Many natural products, such as alkaloids, terpenes, and steroids, contain ring systems that are essential for their biological activity. The process of cyclization (环化) can occur through several mechanisms, including intramolecular reactions where a functional group on a molecule reacts with another part of the same molecule to form a ring. For example, in the synthesis of certain pharmaceuticals, chemists often employ cyclization (环化) reactions to create complex ring structures that are necessary for the drug's efficacy.There are two main types of cyclization (环化): homocyclization and heterocyclization. Homocyclization involves the formation of a ring from atoms of the same type, usually carbon atoms, while heterocyclization involves the incorporation of different types of atoms, such as nitrogen or oxygen, into the ring structure. This distinction is important because the presence of heteroatoms can significantly alter the chemical properties and biological activities of the resulting compounds.Moreover, the thermodynamics and kinetics of cyclization (环化) reactions play a vital role in determining the feasibility and efficiency of these transformations. Some cyclization (环化) reactions may require specific conditions, such as heat or catalysts, to proceed effectively. Understanding these factors allows chemists to optimize reaction conditions and yield the desired products more efficiently.In addition to its importance in synthetic chemistry, cyclization (环化) also plays a critical role in biological systems. Many enzymes catalyze cyclization (环化) reactions as part of metabolic pathways. For instance, the biosynthesis of certain amino acids and nucleotides involves cyclization (环化) steps that are essential for the proper functioning of living organisms. These biological cyclization (环化) processes highlight the interconnectedness of chemistry and life, showcasing how fundamental chemical transformations underpin biological functions.In conclusion, cyclization (环化) is a pivotal concept in organic chemistry that encompasses the formation of cyclic compounds from acyclic precursors. Its significance spans synthetic applications in pharmaceuticals and natural products, as well as vital roles in biological systems. By studying cyclization (环化), chemists can unlock new pathways for molecular creation and gain insights into the intricate relationships between structure and function in both chemical and biological contexts. As research continues to advance, the understanding of cyclization (环化) will undoubtedly lead to innovative discoveries and applications in various scientific fields.

环化是有机化学中的一个重要过程，指的是从线性或非环状前体形成环状化合物的过程。这一转变非常重要，因为它通常会导致分子具有独特的性质和反应性，这些特性在其开链对应物中并不存在。cyclization（环化）的概念可以在各种生化过程中、合成途径和天然产物形成中观察到。理解cyclization（环化）是如何发生的及其在不同领域的影响，可以增强我们对分子设计和反应机制的理解。在有机合成中，创造环状结构的能力是无价的。许多天然产物，如生物碱、萜类和类固醇，含有环系，这对于它们的生物活性至关重要。cyclization（环化）的过程可以通过几种机制发生，包括分子内反应，其中分子上的一个官能团与同一分子的另一部分反应形成一个环。例如，在某些药物的合成中，化学家们常常采用cyclization（环化）反应来创建药物有效性所需的复杂环结构。cyclization（环化）主要有两种类型：同环化和异环化。同环化涉及由相同类型的原子（通常是碳原子）形成一个环，而异环化则涉及将不同类型的原子（如氮或氧）纳入环结构。这一区别很重要，因为异原子的存在可以显著改变生成化合物的化学性质和生物活性。此外，cyclization（环化）反应的热力学和动力学在决定这些转变的可行性和效率方面发挥着重要作用。有些cyclization（环化）反应可能需要特定条件，比如热量或催化剂，才能有效进行。理解这些因素使化学家能够优化反应条件，更有效地获得所需产品。除了在合成化学中的重要性外，cyclization（环化）在生物系统中也扮演着关键角色。许多酶催化cyclization（环化）反应，作为代谢途径的一部分。例如，某些氨基酸和核苷酸的生物合成涉及cyclization（环化）步骤，这对于生物体的正常功能至关重要。这些生物cyclization（环化）过程突显了化学和生命之间的相互联系，展示了基本化学转变如何支撑生物功能。总之，cyclization（环化）是有机化学中的一个关键概念，涵盖了从非环状前体形成环状化合物的过程。它的重要性横跨药物和天然产品的合成应用，以及在生物系统中的重要角色。通过研究cyclization（环化），化学家可以解锁分子创造的新途径，并深入了解化学和生物背景下结构与功能之间的复杂关系。随着研究的不断推进，对cyclization（环化）的理解无疑会导致各个科学领域的创新发现和应用。