basal body

简明释义

基部小体

英英释义

例句

1.Mutations in genes related to the basal body can lead to various diseases.

与基体相关的基因突变可能导致各种疾病。

2.The structure of the flagellum is anchored to the cell by a basal body.

鞭毛的结构通过一个基体锚定在细胞上。

3.The basal body plays a crucial role in the formation of flagella and cilia.

基体在鞭毛和纤毛的形成中起着至关重要的作用。

4.Researchers are studying the function of the basal body in cellular motility.

研究人员正在研究基体在细胞运动中的功能。

5.In ciliates, each cilium originates from a basal body that organizes its microtubules.

在纤毛虫中，每个纤毛都起源于一个组织其微管的基体。

作文

The term basal body refers to a cellular structure that plays a crucial role in the formation of cilia and flagella, which are essential for cell movement and sensory functions. Understanding the function and significance of the basal body is vital in the study of cell biology and its applications in various fields such as medicine and genetics. In the realm of cell biology, the basal body serves as an anchoring point for microtubules, which are the structural components of cilia and flagella. These organelles are important for motility in many single-celled organisms and also play significant roles in multicellular organisms. For instance, in human cells, cilia are involved in moving mucus out of the respiratory tract, while flagella are responsible for the swimming motion of sperm cells. The proper functioning of these structures is dependent on the integrity and functionality of the basal body. The structure of the basal body is similar to that of a centriole, which is another cellular component involved in cell division. Both structures are composed of microtubules arranged in a specific pattern. The basal body typically consists of nine triplet microtubules arranged in a cylindrical shape. This arrangement is essential for the stability and function of cilia and flagella. When the basal body is compromised, it can lead to defects in cilia and flagella, resulting in various health issues. One of the intriguing aspects of the basal body is its involvement in signaling pathways within the cell. Recent studies have shown that the basal body is not merely a structural component but also plays a role in cellular communication. It has been found to interact with various proteins that are involved in signaling cascades, influencing processes such as cell growth, differentiation, and response to external stimuli. This adds another layer of complexity to our understanding of the basal body and its functions. Moreover, defects in the basal body and associated structures can lead to a range of diseases known as ciliopathies. These genetic disorders arise from malfunctions in cilia and flagella, leading to symptoms that can affect multiple organ systems. For example, conditions like polycystic kidney disease and certain forms of retinal degeneration are linked to abnormalities in the basal body and its related structures. This highlights the importance of studying the basal body not only for understanding basic cellular functions but also for potential therapeutic interventions. In conclusion, the basal body is a fundamental component of eukaryotic cells that plays a critical role in the formation and function of cilia and flagella. Its significance extends beyond mere structural support, as it is involved in cellular signaling and has implications in various diseases. As research continues to uncover the complexities of the basal body, it becomes increasingly clear that this small yet vital structure is essential for maintaining cellular health and function. Understanding the basal body will pave the way for advancements in medical science and could lead to new strategies for treating ciliopathies and other related disorders.

短语basal body指的是一种细胞结构，在纤毛和鞭毛的形成中发挥着至关重要的作用，这些结构对细胞运动和感知功能至关重要。理解basal body的功能和重要性对于细胞生物学及其在医学和遗传学等各个领域的应用至关重要。在细胞生物学领域，basal body作为微管的锚定点，这些微管是纤毛和鞭毛的结构成分。这些细胞器在许多单细胞生物的运动中非常重要，并且在多细胞生物中也起着重要作用。例如，在人类细胞中，纤毛参与将粘液从呼吸道移除，而鞭毛则负责精子细胞的游动。当basal body的完整性和功能受到损害时，会导致纤毛和鞭毛的缺陷，从而引发各种健康问题。basal body的结构与中心粒相似，中心粒是另一种参与细胞分裂的细胞成分。这两种结构都是由以特定模式排列的微管组成。basal body通常由九个三联微管以圆柱形排列组成。这种排列对于纤毛和鞭毛的稳定性和功能至关重要。当basal body受到损害时，可能会导致纤毛和鞭毛的缺陷，从而引发各种健康问题。basal body的一个有趣方面是它在细胞内信号传导通路中的作用。最近的研究表明，basal body不仅仅是一个结构组件，还在细胞通信中发挥作用。发现它与多种参与信号级联反应的蛋白质相互作用，影响细胞生长、分化和对外部刺激的反应等过程。这为我们理解basal body及其功能增添了另一层复杂性。此外，basal body及相关结构的缺陷可能导致一系列称为纤毛病的疾病。这些遗传疾病源于纤毛和鞭毛的功能障碍，导致可能影响多个器官系统的症状。例如，多囊肾病和某些形式的视网膜退化与basal body及其相关结构的异常有关。这突显了研究basal body的重要性，不仅可以理解基础细胞功能，还可以为潜在的治疗干预提供帮助。总之，basal body是真核细胞的基本组成部分，在纤毛和鞭毛的形成和功能中发挥着关键作用。它的重要性超越了单纯的结构支持，因为它参与细胞信号传递，并对各种疾病产生影响。随着研究不断揭示basal body的复杂性，越来越清楚的是，这种小而重要的结构对于维持细胞健康和功能至关重要。理解basal body将为医学科学的进步铺平道路，并可能导致治疗纤毛病和其他相关疾病的新策略。