barbituric acid

简明释义

巴比妥酸

英英释义

例句

1.In pharmacology, barbituric acid (巴比妥酸) is crucial for developing sedatives.

在药理学中，barbituric acid（巴比妥酸）对镇静剂的开发至关重要。

2.The structure of barbituric acid (巴比妥酸) includes a pyrimidine ring.

barbituric acid（巴比妥酸）的结构包含一个嘧啶环。

3.Researchers are studying the effects of barbituric acid (巴比妥酸) derivatives on sleep patterns.

研究人员正在研究barbituric acid（巴比妥酸）衍生物对睡眠模式的影响。

4.The synthesis of various medications often begins with the compound barbituric acid (巴比妥酸).

各种药物的合成通常以化合物barbituric acid（巴比妥酸）为起点。

5.Medical students learn about barbituric acid (巴比妥酸) in their pharmacology courses.

医学生在药理学课程中学习barbituric acid（巴比妥酸）。

作文

Barbituric acid, a compound derived from uracil, is a chemical that has played a significant role in the development of various medications, particularly in the realm of sedatives and anesthetics. This compound was first synthesized in the 1860s and paved the way for the creation of barbiturates, which are derivatives of barbituric acid (巴比妥酸). The discovery of barbituric acid marked a turning point in pharmacology, as it led to the development of drugs that could induce sleep and relieve anxiety. The initial purpose of barbituric acid was not to be used directly as a medication but rather as a precursor to more complex compounds. Researchers quickly recognized the potential of this compound in creating sedative drugs, which were crucial for patients undergoing surgery or suffering from severe insomnia. The introduction of barbiturates revolutionized the field of medicine, providing doctors with powerful tools to manage pain and anxiety. However, the use of barbituric acid and its derivatives came with significant risks. Over time, it became evident that barbiturates had a high potential for addiction and overdose. Patients who were prescribed these medications often found themselves reliant on them, leading to a cycle of dependency that was difficult to break. Additionally, the narrow therapeutic window of barbiturates meant that the difference between a therapeutic dose and a lethal dose was alarmingly small. As the medical community became more aware of the dangers associated with barbiturates, the focus shifted towards safer alternatives. Benzodiazepines emerged as a popular choice, offering similar sedative effects without the same level of risk associated with barbituric acid (巴比妥酸) derivatives. This shift underscored the importance of understanding the properties and effects of chemical compounds like barbituric acid in the context of patient safety. Despite the decline in the use of barbiturates, barbituric acid remains an important compound in organic chemistry and medicinal research. Its structure serves as a foundation for the synthesis of various pharmaceuticals, and ongoing studies continue to explore its potential applications. For example, researchers are investigating how modifications to the barbituric acid structure can lead to new, more effective medications with fewer side effects. In conclusion, barbituric acid is a compound that has had a profound impact on the field of medicine. While its derivatives have been both beneficial and dangerous, the lessons learned from their use have shaped modern pharmacology. The history of barbituric acid is a reminder of the delicate balance between therapeutic benefits and potential harms, emphasizing the need for continued research and caution in the development of new medications. As we move forward, it is essential to remember the complexities associated with compounds like barbituric acid and to strive for advancements that prioritize patient safety and well-being.

巴比妥酸是一种从尿嘧啶衍生的化合物，这种化学物质在多种药物的发展中发挥了重要作用，尤其是在镇静剂和麻醉剂领域。该化合物首次合成于19世纪60年代，为巴比妥类药物的创造铺平了道路，这些药物是巴比妥酸（巴比妥酸）的衍生物。巴比妥酸的发现标志着药理学的一个转折点，因为它导致了能够诱导睡眠和缓解焦虑的药物的开发。巴比妥酸的初始目的并不是直接作为药物使用，而是作为更复杂化合物的前体。研究人员迅速意识到这种化合物在创造镇静药物方面的潜力，这对接受手术或严重失眠的患者至关重要。巴比妥类药物的引入彻底改变了医学领域，为医生提供了强大的工具来管理疼痛和焦虑。然而，巴比妥酸及其衍生物的使用伴随着显著的风险。随着时间的推移，越来越明显的是，巴比妥类药物具有较高的成瘾和过量风险。被处方这些药物的患者经常发现自己依赖于它们，导致了一个难以打破的依赖循环。此外，巴比妥类药物的治疗窗口狭窄，这意味着治疗剂量与致死剂量之间的差异惊人地小。随着医学界对与巴比妥类药物相关的危险的认识加深，重点转向了更安全的替代品。苯二氮卓类药物成为一种流行选择，提供类似的镇静效果，而没有与巴比妥酸（巴比妥酸）衍生物相关的同样高的风险。这一转变强调了在患者安全背景下理解化合物如巴比妥酸的特性和效应的重要性。尽管巴比妥类药物的使用有所下降，巴比妥酸仍然是有机化学和药物研究中的一个重要化合物。它的结构为各种药物的合成提供了基础，正在进行的研究继续探索其潜在应用。例如，研究人员正在调查如何修改巴比妥酸的结构以导致新的、更有效的药物，同时副作用更少。总之，巴比妥酸是一种在医学领域产生深远影响的化合物。虽然它的衍生物既有益又危险，但从它们的使用中获得的教训塑造了现代药理学。巴比妥酸的历史提醒我们，治疗利益与潜在危害之间存在微妙的平衡，强调了在新药物开发中继续研究和谨慎的重要性。随着我们向前发展，牢记与像巴比妥酸这样的化合物相关的复杂性，并努力实现优先考虑患者安全和健康的进步，是至关重要的。