anticodon loop

简明释义

反密码子环

英英释义

例句

1.The anticodon loop plays a key role in ensuring that the correct tRNA binds to the ribosome during translation.

反密码子环在确保正确的tRNA在翻译过程中与核糖体结合方面起着关键作用。

2.Researchers are investigating how modifications in the anticodon loop influence tRNA function and stability.

研究人员正在调查反密码子环中的修饰如何影响tRNA的功能和稳定性。

3.Understanding the dynamics of the anticodon loop can help in designing better antibiotics that target bacterial protein synthesis.

理解反密码子环的动态可以帮助设计更好的抗生素，以针对细菌的蛋白质合成。

4.The structure of the tRNA includes an anticodon loop, which is crucial for matching the correct amino acid during protein synthesis.

tRNA的结构包括一个反密码子环，它对于在蛋白质合成过程中匹配正确的氨基酸至关重要。

5.In genetic studies, mutations in the anticodon loop can lead to misreading of mRNA, affecting protein production.

在遗传研究中，反密码子环中的突变可能导致mRNA的错误解读，从而影响蛋白质的生产。

作文

The process of protein synthesis is a fundamental aspect of biology that involves the translation of genetic information into functional proteins. One of the critical components of this process is transfer RNA (tRNA), which plays a vital role in decoding the messenger RNA (mRNA) sequence. Within the structure of tRNA, there exists a specific region known as the anticodon loop, which is essential for the accurate translation of codons during protein synthesis. The anticodon loop consists of three nucleotides that are complementary to the corresponding codon on the mRNA strand. This complementary pairing ensures that the correct amino acid is added to the growing polypeptide chain, thereby maintaining the fidelity of protein synthesis.Understanding the function of the anticodon loop requires an appreciation of its role in the larger context of molecular biology. When a ribosome synthesizes a protein, it reads the sequence of codons on the mRNA, which are sets of three nucleotides that code for specific amino acids. Each tRNA molecule carries a specific amino acid and has an anticodon loop that matches the codon on the mRNA. For instance, if the mRNA has a codon sequence of AUG, the tRNA with the anticodon loop UAC will bind to it, bringing the amino acid methionine into the growing chain.The importance of the anticodon loop extends beyond mere translation accuracy. It also plays a role in the regulation of gene expression and the overall efficiency of protein synthesis. If the anticodon loop is mismatched or altered, it can lead to the incorporation of incorrect amino acids, resulting in dysfunctional proteins that may cause diseases or cellular malfunctions. Thus, the integrity of the anticodon loop is crucial for maintaining cellular health and function.In addition to its biological significance, studying the anticodon loop has practical implications in biotechnology and medicine. For example, researchers can manipulate tRNA molecules to create synthetic versions that can introduce modified amino acids into proteins. This technology has potential applications in drug development and the production of novel biomaterials. Furthermore, understanding how the anticodon loop interacts with mRNA can provide insights into the mechanisms of antibiotic resistance, as certain antibiotics target the translation process by disrupting this interaction.In conclusion, the anticodon loop is a small but powerful element of the tRNA structure that plays a significant role in the accuracy and efficiency of protein synthesis. Its ability to ensure the correct pairing with mRNA codons is vital for producing functional proteins and maintaining cellular health. As research continues to explore the complexities of molecular biology, the anticodon loop remains a key focus area, highlighting its importance not only in fundamental science but also in applied fields such as medicine and biotechnology.

蛋白质合成过程是生物学中的一个基本方面，涉及将遗传信息翻译成功能性蛋白质。这个过程的一个关键组成部分是转运RNA（tRNA），它在解码信使RNA（mRNA）序列中发挥着重要作用。在tRNA的结构中，有一个特定区域称为反密码环，对于蛋白质合成中的准确翻译至关重要。反密码环由三个核苷酸组成，这些核苷酸与mRNA链上的相应密码子互补。这种互补配对确保了正确的氨基酸被添加到不断增长的多肽链中，从而维持蛋白质合成的准确性。理解反密码环的功能需要对其在分子生物学更大背景下的作用有一定的认识。当核糖体合成蛋白质时，它读取mRNA上的密码子序列，这些密码子是三核苷酸的集合，编码特定的氨基酸。每个tRNA分子携带特定的氨基酸，并具有与mRNA上的密码子匹配的反密码环。例如，如果mRNA具有AUG的密码子序列，那么具有反密码环 UAC的tRNA将与之结合，将氨基酸甲硫氨酸带入增长链中。反密码环的重要性不仅仅局限于翻译的准确性。它还在基因表达调控和整体蛋白质合成效率中发挥作用。如果反密码环不匹配或改变，可能会导致错误氨基酸的引入，从而导致功能失常的蛋白质，这可能导致疾病或细胞功能障碍。因此，反密码环的完整性对于维持细胞健康和功能至关重要。除了其生物学意义外，研究反密码环在生物技术和医学中也具有实际意义。例如，研究人员可以操控tRNA分子，创造合成版本，以便将修饰过的氨基酸引入蛋白质中。这项技术在药物开发和新型生物材料的生产中具有潜在应用。此外，理解反密码环如何与mRNA相互作用可以提供有关抗生素耐药机制的洞察，因为某些抗生素通过破坏这种相互作用来靶向翻译过程。总之，反密码环是tRNA结构中的一个小但强大的元素，在蛋白质合成的准确性和效率中发挥着重要作用。它确保与mRNA密码子的正确配对的能力对于产生功能性蛋白质和维持细胞健康至关重要。随着研究继续探索分子生物学的复杂性，反密码环仍然是一个关键关注领域，突显了它在基础科学以及医学和生物技术等应用领域的重要性。