analytical ultracentrifuge

简明释义

分析超离心机

英英释义

例句

1.The analytical ultracentrifuge allows scientists to study the sedimentation behavior of nanoparticles.

通过分析超离心机，科学家可以研究纳米颗粒的沉降行为。

2.Using an analytical ultracentrifuge is essential for characterizing the molecular weight distribution of polymers.

使用分析超离心机对于表征聚合物的分子量分布至关重要。

3.By employing an analytical ultracentrifuge, we can obtain precise measurements of macromolecular interactions.

通过使用分析超离心机，我们可以获得大分子相互作用的精确测量。

4.The research team used the analytical ultracentrifuge to separate proteins based on their size and density.

研究团队使用分析超离心机根据蛋白质的大小和密度进行分离。

5.The data obtained from the analytical ultracentrifuge can help in understanding the stability of colloidal systems.

从分析超离心机获得的数据可以帮助理解胶体系统的稳定性。

作文

The field of biochemistry is vast and complex, encompassing various techniques and tools that scientists use to analyze biological macromolecules. One such powerful tool is the analytical ultracentrifuge, which plays a crucial role in the study of proteins, nucleic acids, and other biomolecules. The analytical ultracentrifuge (分析超离心机) is a sophisticated instrument that utilizes centrifugal force to separate and analyze particles in a solution based on their size, shape, and density. This technique allows researchers to gain insights into the molecular characteristics of substances, making it indispensable in both research and industrial applications.At its core, the analytical ultracentrifuge operates by spinning samples at extremely high speeds, often exceeding 100,000 revolutions per minute. This rapid rotation generates a strong centrifugal force that causes particles in the sample to migrate according to their mass and shape. As a result, heavier and denser particles move towards the bottom of the centrifuge, while lighter ones remain suspended near the top. The ability to visualize and quantify these separations is what makes the analytical ultracentrifuge particularly valuable.One of the key advantages of using an analytical ultracentrifuge is its capacity to provide detailed information about the sedimentation behavior of macromolecules. By analyzing the sedimentation coefficient, scientists can infer the molecular weight and shape of the particles. This data is essential for understanding the structure and function of biomolecules, as well as their interactions with other molecules. For example, in protein studies, the sedimentation behavior can reveal whether a protein is in a monomeric or oligomeric state, which is critical for elucidating its biological function.Moreover, modern analytical ultracentrifuges are equipped with advanced optical systems that enable real-time monitoring of the sedimentation process. This capability allows researchers to perform experiments under various conditions, such as different temperatures and solvent compositions, providing a comprehensive view of how environmental factors influence molecular behavior. The integration of these technologies has significantly enhanced the versatility and applicability of analytical ultracentrifuges in scientific research.In addition to fundamental research, the analytical ultracentrifuge finds applications in various industries, including pharmaceuticals and biotechnology. For instance, it is commonly used in the development of drug formulations, where understanding the stability and behavior of active pharmaceutical ingredients is essential. By employing the analytical ultracentrifuge, scientists can optimize formulations to ensure efficacy and safety before they reach the market.Furthermore, the analytical ultracentrifuge is also instrumental in quality control processes. Manufacturers can utilize this technology to assess the purity and concentration of their products, ensuring that they meet regulatory standards. This aspect is particularly important in the production of biologics, where even minor impurities can have significant implications for patient safety.In conclusion, the analytical ultracentrifuge (分析超离心机) is a vital tool in the realm of biochemical research and industrial applications. Its ability to separate and analyze macromolecules based on their physical properties provides invaluable insights into their structure and function. As technology continues to advance, the capabilities of the analytical ultracentrifuge will likely expand, further enhancing our understanding of the molecular world and its implications for science and medicine.

生物化学领域广阔而复杂，涵盖了科学家用来分析生物大分子的各种技术和工具。其中一个强大的工具是分析超离心机，它在蛋白质、核酸和其他生物分子的研究中发挥着关键作用。分析超离心机是一种复杂的仪器，利用离心力根据粒子的大小、形状和密度分离和分析溶液中的颗粒。这项技术使研究人员能够深入了解物质的分子特性，使其在研究和工业应用中不可或缺。分析超离心机的核心原理是通过以极高的速度旋转样品，通常超过每分钟100,000转。这种快速旋转产生强大的离心力，导致样品中的颗粒根据其质量和形状迁移。因此，较重和较密的颗粒会向离心机底部移动，而较轻的颗粒则保持悬浮在顶部。能够可视化和量化这些分离是使分析超离心机特别有价值的原因。使用分析超离心机的一个主要优势是它能够提供关于大分子沉降行为的详细信息。通过分析沉降系数，科学家可以推断颗粒的分子量和形状。这些数据对于理解生物分子的结构和功能以及它们与其他分子的相互作用至关重要。例如，在蛋白质研究中，沉降行为可以揭示蛋白质是单体还是寡聚体状态，这对阐明其生物功能至关重要。此外，现代分析超离心机配备了先进的光学系统，可以实时监测沉降过程。这种能力使研究人员能够在不同条件下进行实验，例如不同的温度和溶剂组成，从而全面了解环境因素如何影响分子行为。这些技术的整合显著增强了分析超离心机在科学研究中的多功能性和适用性。除了基础研究外，分析超离心机还在制药和生物技术等各个行业中找到了应用。例如，它通常用于药物配方的开发，其中了解活性药物成分的稳定性和行为至关重要。通过使用分析超离心机，科学家可以优化配方，以确保在上市之前的有效性和安全性。此外，分析超离心机在质量控制过程中也起着重要作用。制造商可以利用这项技术评估其产品的纯度和浓度，确保其符合监管标准。这一方面在生物制品的生产中尤为重要，因为即使是微小的杂质也可能对患者安全产生重大影响。总之，分析超离心机是生化研究和工业应用领域的重要工具。它根据物理特性分离和分析大分子的能力为我们提供了对其结构和功能的宝贵见解。随着技术的不断进步，分析超离心机的能力可能会进一步扩展，进一步增强我们对分子世界及其对科学和医学影响的理解。