amino acid sequence

简明释义

氨基酸序列

英英释义

例句

1.The study focused on the *amino acid sequence* of the protein to determine its function.

这项研究集中于蛋白质的*氨基酸序列*以确定其功能。

2.Comparing the *amino acid sequence* across species can reveal evolutionary relationships.

比较不同物种的*氨基酸序列*可以揭示进化关系。

3.The *amino acid sequence* is crucial for understanding how enzymes work.

了解酶的工作原理时，*氨基酸序列*是至关重要的。

4.Researchers used the *amino acid sequence* to identify mutations that could lead to disease.

研究人员使用*氨基酸序列*来识别可能导致疾病的突变。

5.Bioinformatics tools can analyze the *amino acid sequence* and predict protein structure.

生物信息学工具可以分析*氨基酸序列*并预测蛋白质结构。

作文

The study of proteins and their functions is a cornerstone of molecular biology. At the heart of this study lies the concept of the amino acid sequence, which refers to the specific order in which amino acids are arranged in a protein. This sequence is crucial because it determines how the protein will fold and function within a biological system. Proteins are composed of long chains of amino acids, and there are 20 different amino acids that can be combined in various sequences to create a vast array of proteins, each with unique properties and functions.Understanding the amino acid sequence is essential for several reasons. Firstly, it provides insight into the protein's structure. The primary structure of a protein is simply its amino acid sequence. However, the way this sequence folds into secondary and tertiary structures is influenced by the chemical properties of the individual amino acids. For instance, hydrophobic amino acids tend to cluster together away from water, while hydrophilic amino acids are found on the surface of the protein. This folding process is critical, as the final shape of the protein directly impacts its ability to perform its designated function.Moreover, the amino acid sequence plays a significant role in determining the functionality of enzymes, hormones, and antibodies. Enzymes, which catalyze biochemical reactions, rely on their specific amino acid sequence to create an active site that binds to substrates. Any alteration in the sequence, whether through mutation or environmental factors, can lead to changes in enzyme activity or even complete loss of function. This highlights the importance of studying amino acid sequences in understanding diseases caused by protein misfolding or malfunction.In addition to their structural roles, proteins also serve as signaling molecules. Hormones like insulin have very specific amino acid sequences that allow them to interact with receptors on target cells. This interaction triggers a cascade of cellular responses, demonstrating how the precise arrangement of amino acids is vital for communication within and between cells.The field of bioinformatics has emerged as a powerful tool in analyzing amino acid sequences. With the advent of high-throughput sequencing technologies, researchers can now determine the amino acid sequences of thousands of proteins quickly. This data can be used to predict protein function, understand evolutionary relationships, and identify potential drug targets. For example, comparing the amino acid sequences of similar proteins across different species can provide insights into how proteins have evolved and adapted to various environments.In conclusion, the amino acid sequence is a fundamental aspect of protein biology that underpins many processes in living organisms. By studying these sequences, scientists can gain valuable insights into protein structure, function, and the mechanisms underlying various biological phenomena. As research continues to advance, the significance of understanding amino acid sequences will only grow, paving the way for new discoveries in medicine, biotechnology, and beyond.

蛋白质及其功能的研究是分子生物学的基石。在这一研究的核心是“氨基酸序列”的概念，它指的是氨基酸在蛋白质中排列的特定顺序。这个序列至关重要，因为它决定了蛋白质在生物系统中的折叠和功能。蛋白质由长链氨基酸组成，而可以组合成各种序列的氨基酸有20种，每种组合形成独特的蛋白质，具有独特的性质和功能。理解“氨基酸序列”是至关重要的，原因有几个。首先，它提供了对蛋白质结构的洞察。蛋白质的初级结构仅仅是其“氨基酸序列”。然而，这一序列如何折叠成二级和三级结构受到个别氨基酸化学性质的影响。例如，疏水性氨基酸往往聚集在一起远离水，而亲水性氨基酸则位于蛋白质的表面。这一折叠过程至关重要，因为蛋白质的最终形状直接影响其执行指定功能的能力。此外，“氨基酸序列”在决定酶、激素和抗体的功能方面也起着重要作用。酶作为催化生化反应的分子，依赖于其特定的“氨基酸序列”来创建一个与底物结合的活性位点。序列中的任何改变，无论是通过突变还是环境因素，都可能导致酶活性的变化，甚至完全失去功能。这突显了研究“氨基酸序列”在理解由蛋白质错误折叠或功能失常引起的疾病中的重要性。除了结构作用，蛋白质还作为信号分子发挥作用。像胰岛素这样的激素具有非常特定的“氨基酸序列”，使其能够与靶细胞上的受体相互作用。这种相互作用触发了一系列细胞反应，展示了氨基酸的精确排列对细胞内外通信的重要性。生物信息学领域的出现为分析“氨基酸序列”提供了强大的工具。随着高通量测序技术的出现，研究人员现在可以快速确定成千上万种蛋白质的“氨基酸序列”。这些数据可用于预测蛋白质功能、理解进化关系以及识别潜在的药物靶点。例如，比较不同物种间相似蛋白质的“氨基酸序列”可以提供关于蛋白质如何进化和适应各种环境的见解。总之，“氨基酸序列”是蛋白质生物学的基本方面，支撑着生物体内的许多过程。通过研究这些序列，科学家们可以获得关于蛋白质结构、功能以及各种生物现象背后机制的宝贵见解。随着研究的不断推进，理解“氨基酸序列”的重要性将只会增加，为医学、生物技术等领域的新发现铺平道路。