amide linkage

简明释义

酰胺结合

英英释义

例句

1.The stability of proteins is partly due to the presence of amide linkages 酰胺键 in their backbone.

蛋白质的稳定性部分归因于其骨架中存在的酰胺键。

2.In organic chemistry, understanding how to create an amide linkage 酰胺键 can help in designing new drugs.

在有机化学中，了解如何创建酰胺键可以帮助设计新药物。

3.The formation of an amide linkage 酰胺键 is crucial in protein synthesis.

在蛋白质合成中，酰胺键的形成至关重要。

4.Biopolymers often contain amide linkages 酰胺键 that contribute to their structural integrity.

生物聚合物通常含有酰胺键，这有助于它们的结构完整性。

5.The reaction between an acid and an amine results in an amide linkage 酰胺键.

酸与胺之间的反应会产生酰胺键。

作文

In the realm of biochemistry, the understanding of molecular structures is paramount. One such crucial structure is the amide linkage, which plays a significant role in the formation of proteins and other biological macromolecules. An amide linkage refers to the bond that forms between a carbon atom of a carboxylic acid and a nitrogen atom of an amine, resulting in the release of a molecule of water—a process known as dehydration synthesis. This reaction is fundamental to the formation of peptides, which are short chains of amino acids linked by amide linkages. The importance of amide linkages cannot be overstated, as they are essential for the structure and function of proteins. Proteins, which are vital for numerous biological processes, are composed of long chains of amino acids connected by amide linkages. The sequence and arrangement of these amino acids determine the protein's unique three-dimensional shape, which in turn affects its functionality. For instance, enzymes, which are proteins that catalyze biochemical reactions, rely on their specific shapes to bind substrates effectively. Any alteration in the amide linkages within a protein can lead to misfolding, resulting in loss of function and potentially causing diseases such as Alzheimer's or cystic fibrosis.Furthermore, amide linkages are not limited to proteins; they also appear in various natural and synthetic polymers. For example, nylon, a widely used synthetic polymer, contains amide linkages in its structure, contributing to its strength and durability. The presence of amide linkages in such materials allows for a range of applications, from textiles to engineering components. Understanding how these linkages contribute to the properties of materials can aid in the development of new substances with desirable characteristics.In summary, the amide linkage is a fundamental chemical bond that underpins many aspects of biology and materials science. Its role in protein structure and function highlights the intricate connections between molecular composition and biological activity. As research continues to explore the complexities of molecular interactions, the significance of amide linkages remains a focal point in both academic and applied sciences. By studying these linkages, scientists can gain insights into the mechanisms of life at the molecular level, paving the way for advancements in medicine, biotechnology, and materials engineering. Ultimately, the amide linkage exemplifies how a single type of bond can have far-reaching implications across diverse fields, illustrating the beauty and complexity of chemistry in our world.

在生物化学领域，理解分子结构至关重要。其中一个关键结构是酰胺键，它在蛋白质和其他生物大分子的形成中发挥着重要作用。酰胺键是指羧酸的碳原子与胺的氮原子之间形成的键，这一过程释放出水分子——这一过程被称为脱水合成。这一反应是肽的形成基础，肽是由通过酰胺键连接在一起的氨基酸短链。酰胺键的重要性不容小觑，因为它们对于蛋白质的结构和功能至关重要。蛋白质是众多生物过程所必需的，由通过酰胺键连接在一起的长链氨基酸组成。这些氨基酸的序列和排列决定了蛋白质独特的三维形状，而这又影响其功能。例如，酶是催化生化反应的蛋白质，它们依赖于特定的形状来有效地结合底物。任何对蛋白质中酰胺键的改变都可能导致错误折叠，从而导致功能丧失，并可能引发如阿尔茨海默病或囊性纤维化等疾病。此外，酰胺键不仅限于蛋白质；它们还出现在各种天然和合成聚合物中。例如，尼龙是一种广泛使用的合成聚合物，其结构中包含酰胺键，使其具有强度和耐用性。酰胺键在此类材料中的存在使其能够应用于从纺织品到工程组件的多个领域。理解这些键如何影响材料的特性可以帮助开发具有理想特性的新的物质。总之，酰胺键是一种基本的化学键，支撑着生物学和材料科学的许多方面。它在蛋白质的结构和功能中的作用突显了分子组成与生物活性之间的复杂联系。随着研究继续探索分子相互作用的复杂性，酰胺键的重要性仍然是学术界和应用科学的一个重点。通过研究这些键，科学家可以深入了解生命在分子水平上的机制，为医学、生物技术和材料工程的进步铺平道路。最终，酰胺键展示了单一类型的键如何在不同领域产生深远的影响，揭示了我们世界中化学的美丽和复杂性。