amide bond

简明释义

酰胺结合

英英释义

例句

1.The formation of an amide bond 酰胺键 is a crucial step in protein synthesis.

形成一个酰胺键 amide bond 是蛋白质合成中的关键步骤。

2.The properties of polymers can be significantly altered by modifying the amide bonds 酰胺键 within their structure.

通过修改聚合物结构中的酰胺键 amide bonds，可以显著改变其性质。

3.Researchers are exploring new catalysts to facilitate the formation of amide bonds 酰胺键 in synthetic processes.

研究人员正在探索新的催化剂，以促进合成过程中的酰胺键 amide bond 的形成。

4.In organic chemistry, the reaction between a carboxylic acid and an amine results in an amide bond 酰胺键.

在有机化学中，羧酸和胺之间的反应会产生一个酰胺键 amide bond。

5.The stability of the amide bond 酰胺键 is essential for the integrity of many pharmaceuticals.

许多药物的完整性依赖于酰胺键 amide bond 的稳定性。

作文

The study of organic chemistry often leads us to explore various types of chemical bonds that play crucial roles in the structure and function of biomolecules. One such bond is the amide bond, which is formed between a carboxylic acid and an amine. This bond is of paramount importance in the formation of proteins, as it links amino acids together in a polypeptide chain. Understanding the nature of the amide bond is essential for anyone studying biochemistry or molecular biology.An amide bond is characterized by a carbonyl group (C=O) directly attached to a nitrogen atom (N). The formation of this bond involves a condensation reaction, where a molecule of water is released as the carboxylic acid and amine react with each other. This process is not only fundamental in the synthesis of proteins but also in the formation of other important biological molecules such as nucleic acids and certain lipids.The stability of the amide bond contributes to the overall structure of proteins. Unlike other types of bonds, such as ester or ether bonds, amide bonds exhibit resonance, which allows them to maintain a partial double bond character. This resonance stabilizes the bond and influences the three-dimensional conformation of proteins. As a result, the presence of amide bonds is critical in determining how proteins fold and function.In addition to their structural importance, amide bonds also play a role in the biological activity of enzymes and hormones. Many enzymes are proteins that rely on the precise arrangement of amino acids connected by amide bonds to perform their catalytic functions. Similarly, hormones such as insulin are composed of chains of amino acids linked by amide bonds, which are essential for their biological activity.Furthermore, the properties of amide bonds can be exploited in various fields, including pharmaceuticals and materials science. For instance, many drugs are designed to target specific proteins by interacting with their amide bonds. Understanding the chemistry of these bonds can lead to the development of more effective medications. In materials science, amide bonds are found in polymers such as nylon, which are known for their strength and durability.In conclusion, the amide bond is a fundamental component in the world of organic chemistry, particularly in the context of biological macromolecules. Its unique characteristics not only contribute to the structural integrity of proteins but also influence their functional properties. A thorough understanding of amide bonds is essential for anyone pursuing a career in the life sciences, as it lays the foundation for comprehending the complex interactions that govern biological systems. The significance of amide bonds extends beyond biology, impacting fields such as medicine and materials engineering, making them a topic worthy of in-depth study and appreciation.

有机化学的研究常常引导我们探索在生物分子的结构和功能中起关键作用的各种化学键。其中一种键是酰胺键，它是在羧酸和胺之间形成的。这种键在蛋白质的形成中至关重要，因为它将氨基酸连接在一起形成多肽链。理解酰胺键的性质对于任何学习生物化学或分子生物学的人来说都是必不可少的。酰胺键的特征在于一个羰基（C=O）直接连接到一个氮原子（N）。这种键的形成涉及一个缩合反应，其中当羧酸和胺相互反应时，释放出一分子水。这一过程不仅是蛋白质合成的基础，也是某些重要生物分子如核酸和某些脂质形成的基础。酰胺键的稳定性有助于蛋白质的整体结构。与酯键或醚键等其他类型的键不同，酰胺键表现出共振，这使得它们保持部分双键特性。这种共振稳定了该键并影响蛋白质的三维构象。因此，酰胺键的存在在决定蛋白质折叠和功能方面至关重要。除了结构重要性外，酰胺键还在酶和激素的生物活性中发挥作用。许多酶是依赖于通过酰胺键连接的氨基酸的精确排列来执行催化功能的蛋白质。同样，像胰岛素这样的激素由通过酰胺键连接的氨基酸链组成，这对它们的生物活性至关重要。此外，酰胺键的性质可以在药物和材料科学等各个领域得到利用。例如，许多药物旨在通过与其酰胺键相互作用来靶向特定蛋白质。理解这些键的化学可以导致更有效药物的发展。在材料科学中，酰胺键出现在尼龙等聚合物中，这些聚合物以其强度和耐用性而闻名。总之，酰胺键是有机化学世界中的一个基本组成部分，特别是在生物大分子的背景下。它独特的特性不仅有助于蛋白质的结构完整性，还影响其功能特性。全面理解酰胺键对于任何追求生命科学职业的人来说都是必不可少的，因为它为理解支配生物系统的复杂相互作用奠定了基础。酰胺键的重要性超越了生物学，影响着医药和材料工程等领域，使其成为值得深入研究和欣赏的主题。