allelic sequence

简明释义

等位序列

英英释义

例句

1.By comparing the allelic sequence of different species, we can trace evolutionary relationships.

通过比较不同物种的等位基因序列，我们可以追踪进化关系。

2.The researcher analyzed the allelic sequence to determine genetic variations among the population.

研究人员分析了等位基因序列以确定人群中的遗传变异。

3.The allelic sequence of a specific gene can influence traits such as height and eye color.

特定基因的等位基因序列可以影响身高和眼睛颜色等性状。

4.The allelic sequence associated with the disease was identified through genome-wide association studies.

通过全基因组关联研究，识别出了与该疾病相关的等位基因序列。

5.Understanding the allelic sequence can help in developing targeted therapies for genetic disorders.

理解等位基因序列有助于开发针对遗传疾病的靶向治疗。

作文

In the study of genetics, understanding the concept of allelic sequence is crucial for deciphering the complexities of heredity and variation among organisms. An allelic sequence refers to the specific sequence of nucleotides that make up an allele, which is a variant form of a gene. Genes, the fundamental units of heredity, can exist in multiple forms due to mutations or variations in their DNA sequence. These different forms are known as alleles. The allelic sequence determines the traits expressed by an organism, influencing characteristics such as eye color, height, and susceptibility to diseases.To illustrate this concept, consider the gene responsible for flower color in pea plants, famously studied by Gregor Mendel. This gene can have various alleles, each with a distinct allelic sequence. For instance, one allele may code for purple flowers, while another codes for white flowers. The differences in the allelic sequence of these alleles lead to the observable phenotypic variations in the plants. When Mendel cross-pollinated plants with different allelic sequences, he was able to observe patterns of inheritance, laying the groundwork for modern genetics.The significance of allelic sequences extends beyond simple Mendelian traits. In complex traits, which are influenced by multiple genes, the interactions between different allelic sequences can create a wide range of phenotypes. For example, human height is a polygenic trait, meaning it is affected by many genes, each contributing a small effect. Researchers studying the allelic sequences associated with height can identify specific genetic variants that influence growth patterns, helping to unravel the genetic architecture of this trait.Moreover, the study of allelic sequences plays a vital role in medical genetics. Understanding the variations in allelic sequences can aid in identifying genetic predispositions to certain diseases. For instance, specific alleles of the BRCA1 and BRCA2 genes are linked to an increased risk of breast and ovarian cancer. By analyzing the allelic sequences of these genes, healthcare professionals can assess an individual's risk and recommend appropriate preventive measures.The advent of technologies such as next-generation sequencing has revolutionized our ability to analyze allelic sequences on a large scale. Researchers can now sequence entire genomes, allowing them to compare allelic sequences across populations and species. This comparative genomics approach provides insights into evolutionary relationships and the mechanisms of adaptation. For example, by examining the allelic sequences of different species, scientists can trace the evolutionary history of specific traits, such as resistance to environmental stressors.In conclusion, the concept of allelic sequence is fundamental to our understanding of genetics and its applications in various fields. From explaining the inheritance of traits to uncovering the genetic basis of diseases, allelic sequences provide a window into the molecular underpinnings of life. As research continues to advance, the knowledge gained from studying allelic sequences will undoubtedly lead to further breakthroughs in medicine, agriculture, and our overall understanding of biological diversity.

在遗传学研究中，理解等位序列的概念对解读生物体之间遗传和变异的复杂性至关重要。等位序列指的是构成等位基因的核苷酸的特定序列，而等位基因是基因的一种变异形式。基因是遗传的基本单位，由于突变或DNA序列的变异，它们可以以多种形式存在。这些不同的形式被称为等位基因。等位序列决定了生物体表达的性状，影响特征如眼睛颜色、身高和疾病易感性。为了说明这一概念，考虑豌豆植物中负责花色的基因，这一基因曾被格里戈尔·孟德尔著名地研究。这个基因可以有不同的等位基因，每个等位基因都有独特的等位序列。例如，一个等位基因可能编码紫色花朵，而另一个则编码白色花朵。这些等位基因的等位序列的差异导致植物中可观察到的表型变化。当孟德尔进行不同等位序列的植物杂交时，他能够观察到遗传模式，为现代遗传学奠定了基础。等位序列的重要性不仅限于简单的孟德尔性状。在复杂性状中，受多个基因影响，不同等位序列之间的相互作用可以产生广泛的表型。例如，人类身高就是一种多基因性状，意味着它受到许多基因的影响，每个基因贡献微小的效应。研究与身高相关的等位序列的研究人员可以识别出影响生长模式的特定遗传变异，从而帮助揭示这一性状的遗传结构。此外，等位序列的研究在医学遗传学中也发挥着至关重要的作用。了解等位序列的变异可以帮助识别某些疾病的遗传易感性。例如，BRCA1和BRCA2基因的特定等位基因与乳腺癌和卵巢癌的风险增加有关。通过分析这些基因的等位序列，医疗专业人员可以评估个人的风险并建议适当的预防措施。下一代测序等技术的出现彻底改变了我们在大规模上分析等位序列的能力。研究人员现在可以对整个基因组进行测序，使他们能够比较不同人群和物种的等位序列。这种比较基因组学方法提供了对进化关系和适应机制的深入了解。例如，通过检查不同物种的等位序列，科学家们可以追踪特定性状的进化历史，例如对环境压力源的抵抗力。总之，等位序列的概念是我们理解遗传学及其在各个领域应用的基础。从解释性状的遗传到揭示疾病的遗传基础，等位序列为我们提供了生命分子基础的窗口。随着研究的不断推进，从研究等位序列中获得的知识无疑将导致医学、农业和我们对生物多样性的整体理解的进一步突破。