adrenocorticotropic hormone

简明释义

促肾上腺皮质激素

英英释义

Adrenocorticotropic hormone (ACTH) is a peptide hormone produced by the anterior pituitary gland that stimulates the adrenal glands to release cortisol and other glucocorticoids.

肾上腺皮质促激素(ACTH)是一种由前垂体产生的肽类激素,刺激肾上腺释放皮质醇和其他糖皮质激素。

例句

1.The doctor explained that the levels of adrenocorticotropic hormone (促肾上腺皮质激素) in the blood can indicate stress levels.

医生解释说,血液中adrenocorticotropic hormone促肾上腺皮质激素)的水平可以指示压力水平。

2.The pituitary gland produces adrenocorticotropic hormone (促肾上腺皮质激素), which stimulates the adrenal glands.

垂体产生adrenocorticotropic hormone促肾上腺皮质激素),刺激肾上腺。

3.A deficiency in adrenocorticotropic hormone (促肾上腺皮质激素) may lead to adrenal insufficiency.

缺乏adrenocorticotropic hormone促肾上腺皮质激素)可能导致肾上腺功能不足。

4.Researchers are studying how adrenocorticotropic hormone (促肾上腺皮质激素) affects mood and behavior.

研究人员正在研究adrenocorticotropic hormone促肾上腺皮质激素)如何影响情绪和行为。

5.Elevated levels of adrenocorticotropic hormone (促肾上腺皮质激素) can be a sign of Cushing's syndrome.

升高的adrenocorticotropic hormone促肾上腺皮质激素)水平可能是库欣综合症的迹象。

作文

The human body is a complex system, governed by various hormones that regulate numerous physiological processes. One of the key hormones in this intricate network is the adrenocorticotropic hormone, which is often abbreviated as ACTH. This hormone plays a vital role in the stress response and helps to maintain homeostasis within the body. Understanding the function and significance of adrenocorticotropic hormone is crucial for comprehending how our bodies react to stress and other stimuli.The adrenocorticotropic hormone is produced by the pituitary gland, which is located at the base of the brain. When the body encounters stress, whether physical or psychological, the hypothalamus releases corticotropin-releasing hormone (CRH). This hormone then signals the anterior pituitary gland to secrete adrenocorticotropic hormone. Once released into the bloodstream, ACTH travels to the adrenal glands, which are situated on top of the kidneys. In response to ACTH, the adrenal glands produce cortisol, a steroid hormone that plays a critical role in the stress response.Cortisol is often referred to as the 'stress hormone' because its levels rise in response to stress. This hormone has several important functions, including regulating metabolism, reducing inflammation, and controlling the sleep-wake cycle. However, the action of cortisol is dependent on the presence of adrenocorticotropic hormone. Without ACTH, the adrenal glands would not be stimulated to produce cortisol, leading to an inadequate response to stressors.The regulation of adrenocorticotropic hormone is tightly controlled by a feedback mechanism involving cortisol. When cortisol levels rise sufficiently, they signal the hypothalamus and pituitary gland to decrease the production of CRH and ACTH, respectively. This negative feedback loop ensures that cortisol levels remain within a healthy range, preventing the harmful effects of chronic stress, such as immune suppression and weight gain.Dysregulation of adrenocorticotropic hormone can lead to various health issues. For instance, excessive production of ACTH can result in Cushing's disease, characterized by high cortisol levels. This condition can lead to symptoms such as obesity, hypertension, and diabetes. Conversely, insufficient levels of ACTH can cause adrenal insufficiency, where the body does not produce enough cortisol, leading to fatigue, weakness, and low blood pressure.Furthermore, understanding the role of adrenocorticotropic hormone extends beyond just its physiological functions. Research has shown that chronic stress can lead to altered levels of ACTH, which may contribute to mental health disorders such as depression and anxiety. Therefore, maintaining a balanced level of this hormone is essential not only for physical health but also for emotional well-being.In conclusion, the adrenocorticotropic hormone is a crucial component of the body’s endocrine system, playing a significant role in the stress response and overall homeostasis. Its production and regulation are essential for maintaining health, and any imbalance can lead to serious health issues. By understanding the importance of ACTH, we can better appreciate the complexities of our body’s responses to stress and take steps to manage our health effectively.

人体是一个复杂的系统,由多种激素调节许多生理过程。在这个复杂网络中,促肾上腺皮质激素(通常缩写为ACTH)是一个关键激素。该激素在应对压力方面发挥着重要作用,并有助于维持身体内的稳态。理解促肾上腺皮质激素的功能和重要性对于理解我们身体如何对压力和其他刺激作出反应至关重要。促肾上腺皮质激素由位于大脑底部的垂体腺产生。当身体遇到物理或心理压力时,下丘脑释放促肾上腺皮质激素释放激素(CRH)。该激素随后信号前垂体分泌促肾上腺皮质激素。一旦释放到血液中,ACTH便会旅行到位于肾脏顶部的肾上腺。作为对ACTH的反应,肾上腺产生皮质醇,这是一种在应对压力中起关键作用的类固醇激素。皮质醇常被称为“压力激素”,因为其水平会在应对压力时上升。该激素具有几项重要功能,包括调节代谢、减少炎症和控制睡眠-觉醒周期。然而,皮质醇的作用依赖于促肾上腺皮质激素的存在。如果没有ACTH,肾上腺将不会受到刺激以产生皮质醇,从而导致对压力源的反应不足。促肾上腺皮质激素的调节通过涉及皮质醇的反馈机制严格控制。当皮质醇水平足够高时,它会向下丘脑和垂体腺发出减少CRH和ACTH生产的信号。这一负反馈环路确保皮质醇水平保持在健康范围内,防止慢性压力带来的有害影响,如免疫抑制和体重增加。促肾上腺皮质激素的失调可能导致各种健康问题。例如,ACTH的过量产生可能导致库欣病,其特征是皮质醇水平过高。此病症可能导致肥胖、高血压和糖尿病等症状。相反,ACTH水平不足可能导致肾上腺功能不全,身体无法产生足够的皮质醇,导致疲劳、虚弱和低血压。此外,理解促肾上腺皮质激素的作用不仅限于其生理功能。研究表明,慢性压力可能导致ACTH水平改变,这可能促成抑郁症和焦虑症等心理健康障碍。因此,维持这种激素的平衡水平对于身体健康和情感健康都是至关重要的。总之,促肾上腺皮质激素是身体内分泌系统的重要组成部分,在应对压力和整体稳态中发挥着重要作用。其生产和调节对于维持健康至关重要,任何失衡都可能导致严重的健康问题。通过理解ACTH的重要性,我们可以更好地欣赏身体对压力反应的复杂性,并采取措施有效管理我们的健康。