fumarase

简明释义

[/ˈfjuːməreɪs/][/ˈfjuːməreɪs/]

n. [生化] 延胡索酸酶

英英释义

Fumarase is an enzyme that catalyzes the reversible hydration of fumarate to malate in the tricarboxylic acid cycle.

苹果酸酶是一种催化反转水合反应,将富马酸转化为苹果酸的酶,参与三羧酸循环。

单词用法

同义词

fumarate hydratase

富马酸水合酶

Fumarase catalyzes the reversible hydration of fumarate to malate.

富马酸酶催化富马酸向苹果酸的可逆水合作用。

fumarate lyase

富马酸裂解酶

Deficiency in fumarate hydratase can lead to fumaric aciduria.

富马酸水合酶缺乏可能导致富马酸尿症。

反义词

fumarate

富马酸盐

The fumarate ion is a key intermediate in the citric acid cycle.

富马酸盐离子是柠檬酸循环中的一个关键中间体。

malate

苹果酸盐

Malate is often used in biochemical studies to analyze metabolic pathways.

苹果酸在生化研究中常用于分析代谢途径。

例句

1.There also exists a cytosolic fumarase isoenzyme that is involved in DNA damage repair (3).

存在细胞质延胡索酸水合酶的同工酶,参与DNA损伤的修复(3)。

2.There also exists a cytosolic fumarase isoenzyme that is involved in DNA damage repair (3).

存在细胞质延胡索酸水合酶的同工酶,参与DNA损伤的修复(3)。

3.Fumarase (D9C5) Rabbit mAb recognizes endogenous levels of total fumarase protein.

兔单克隆抗体识别内源性的延胡索酸酶总蛋白水平。

4.Specific property of fumarase for immobilized cells was compared with that of free cells.

同时比较了固定化细胞与游离细胞的富马酸酶特性。

5.Deficiencies in fumarase can lead to metabolic disorders.

缺乏fumarase可能导致代谢紊乱。

6.Researchers are studying fumarase to understand its function in cancer metabolism.

研究人员正在研究fumarase以了解其在癌症代谢中的作用。

7.Inhibition of fumarase has been proposed as a therapeutic strategy for certain diseases.

抑制fumarase被提议作为某些疾病的治疗策略。

8.The activity of fumarase can be measured using spectrophotometry.

可以使用光谱法测量fumarase的活性。

9.The enzyme fumarase plays a crucial role in the citric acid cycle.

fumarase在柠檬酸循环中起着至关重要的作用。

作文

Fumarase is an important enzyme that plays a crucial role in the citric acid cycle, also known as the Krebs cycle. This cycle is essential for cellular respiration, which is the process by which cells convert nutrients into energy. The enzyme fumarase catalyzes the reversible hydration of fumarate to malate. This reaction is vital because it helps maintain the balance of various metabolites within the cell. Without fumarase, the citric acid cycle would be disrupted, leading to a decrease in energy production and potentially causing various metabolic disorders.In our daily lives, we often overlook the microscopic processes that sustain our existence. For instance, when we consume food, our body breaks it down into simpler molecules. These molecules then enter the metabolic pathways where enzymes like fumarase come into play. They facilitate reactions that ultimately lead to the production of ATP, the energy currency of the cell. Therefore, understanding the function of fumarase can provide insights into how our bodies work at a fundamental level.The significance of fumarase extends beyond just energy production. Research has shown that mutations in the gene encoding fumarase can lead to fumaric aciduria, a rare genetic disorder characterized by the accumulation of fumarate in the body. This condition can result in neurological issues and other health complications. Thus, studying fumarase not only helps us understand metabolic processes but also highlights the importance of genetic factors in human health.Moreover, the study of fumarase has implications in cancer research. Some tumors have been found to exhibit altered levels of fumarase, suggesting that it may play a role in tumorigenesis. By investigating how fumarase functions and its relationship with other metabolic pathways, scientists hope to uncover new therapeutic targets for cancer treatment.In conclusion, fumarase is more than just a simple enzyme; it is a fundamental component of our metabolic machinery. Its role in the citric acid cycle underscores the intricate connections between various biochemical processes that sustain life. As research continues to uncover the complexities of enzymes like fumarase, we gain a deeper appreciation for the delicate balance of life at the molecular level. Understanding these processes not only enhances our knowledge of biology but also opens doors to potential medical advancements that could improve human health and longevity.

富马酶是一种重要的酶,在柠檬酸循环中发挥着至关重要的作用,这个循环也被称为克雷布斯循环。这个循环对于细胞呼吸是必不可少的,细胞通过这一过程将营养物质转化为能量。酶富马酶催化富马酸与苹果酸之间的可逆水合反应。这个反应至关重要,因为它有助于维持细胞内各种代谢物的平衡。如果没有富马酶,柠檬酸循环将会受到干扰,从而导致能量生产减少,并可能引起各种代谢紊乱。在我们的日常生活中,我们常常忽视支撑我们生存的微观过程。例如,当我们摄入食物时,身体会将其分解为更简单的分子。这些分子随后进入代谢途径,其中像富马酶这样的酶发挥作用。它们促进反应,最终导致ATP的生成,ATP是细胞的能量货币。因此,理解富马酶的功能可以提供对我们身体在基础层面上如何运作的洞察。富马酶的重要性不仅仅局限于能量生产。研究表明,编码富马酶的基因突变可能导致富马酸尿症,这是一种罕见的遗传疾病,其特征是在体内富马酸的积累。这种情况可能导致神经系统问题和其他健康并发症。因此,研究富马酶不仅有助于我们理解代谢过程,还突显了遗传因素在人类健康中的重要性。此外,富马酶的研究在癌症研究中也具有重要意义。一些肿瘤发现其富马酶水平发生改变,这表明它可能在肿瘤发生中发挥作用。通过研究富马酶的功能及其与其他代谢途径的关系,科学家希望揭示癌症治疗的新靶点。总之,富马酶不仅仅是一种简单的酶;它是我们代谢机制的基本组成部分。它在柠檬酸循环中的角色强调了支撑生命的各种生化过程之间错综复杂的联系。随着研究不断揭示像富马酶这样的酶的复杂性,我们对分子层面上生命的微妙平衡有了更深刻的理解。理解这些过程不仅增强了我们对生物学的认识,也为潜在的医学进步打开了大门,这些进步可能改善人类健康和延长寿命。