tautomeric

简明释义

英[ˌtɔːtəˈmɛrɪk]美[ˌtɔːtəˈmɛrɪk]

adj. 互变异构的

英英释义

单词用法

同义词

反义词

例句

1.The tautomeric energies of DHP(HMP)-ethanol clusters is close to that of the isolated solute molecule. It indicates that the solvent molecule have not changed the tautomeric equilibrium.

乙醇分子复合物的互变异构能和孤立溶质分子的互变异构能结果很接近，表明溶剂分子参与反应并没有改变互变异构平衡。

2.The tautomeric equilibrium between the azo type and the hydrazone type of these compounds in different solvents and different acidity has also been studied.

对它们在不同溶剂。 不同酸碱度溶液中的偶氮式及腙式间互变异构平衡进行了研究。

3.A new tautomeric laser dye Kiton red has been synthesized.

本文合成一种具有互变异构性能的新型激光染料奇通红。

4.Resembles thymine, but easily interconverts to tautomeric form that pairs with guanine.

与胸腺嘧啶相似，但很容易转换成与鸟嘌呤配对的互变异构形式。

5.The tautomeric energies of DHP(HMP)-ethanol clusters is close to that of the isolated solute molecule. It indicates that the solvent molecule have not changed the tautomeric equilibrium.

乙醇分子复合物的互变异构能和孤立溶质分子的互变异构能结果很接近，表明溶剂分子参与反应并没有改变互变异构平衡。

6.The entropy effect on the Gibbs free energy of 7-thioguanine base is very small and there is little significance for the tautomeric equilibria of the base.

硫代鸟嘌呤互变异构的熵效应小，对互变异构平衡没有显著的影响，而焓变对互变异构产生了主要的影响。

7.The tautomeric 互变异构体 forms of this molecule can exhibit different biological activities.

这种分子的tautomeric 互变异构体形式可能表现出不同的生物活性。

8.Scientists often study the tautomeric 互变异构体 equilibrium to optimize drug formulations.

科学家们常常研究tautomeric 互变异构体平衡，以优化药物配方。

9.In organic chemistry, tautomeric 互变异构体 relationships are crucial for understanding reaction mechanisms.

在有机化学中，tautomeric 互变异构体关系对于理解反应机制至关重要。

10.The tautomeric 互变异构体 state can influence the solubility of compounds in various solvents.

不同溶剂中，tautomeric 互变异构体状态会影响化合物的溶解度。

11.The compound exists in a tautomeric 互变异构体 form that can easily interconvert.

该化合物以一种可以轻易互变的tautomeric 互变异构体形式存在。

作文

In the field of chemistry, understanding the concept of tautomeric structures is crucial for grasping how certain molecules behave and interact with one another. Tautomerism refers to the phenomenon where compounds exist in two or more interconvertible forms, which are typically distinguished by the relocation of a hydrogen atom and a switch of single and double bonds. This dynamic equilibrium between different forms can significantly affect the properties and reactivity of a compound, making it an essential concept in organic chemistry.For instance, consider the classic example of keto-enol tautomerism. In this case, a ketone can exist in equilibrium with its corresponding enol form. The keto form, characterized by a carbonyl group (C=O), is usually more stable than the enol form, which contains a hydroxyl group (-OH) attached to a carbon-carbon double bond (C=C). However, under certain conditions, such as changes in pH or the presence of catalysts, the enol form can become more prevalent. This shift can have significant implications in various chemical reactions, including those involved in biological systems.The tautomeric relationship between these forms is not just a theoretical concept; it has practical applications in drug design and development. Many pharmaceutical compounds rely on their tautomeric forms to exhibit desired biological activity. For example, some drugs are designed to target specific enzymes that are sensitive to the tautomeric state of the substrate. Understanding the balance between these forms can lead to the development of more effective medications with fewer side effects.Moreover, the study of tautomeric compounds extends beyond simple organic molecules. In biochemistry, nucleic acids such as DNA and RNA can also exhibit tautomerism. The tautomeric forms of nucleobases can affect base pairing during DNA replication and transcription, potentially leading to mutations if the incorrect base is incorporated. This highlights the importance of tautomerism in maintaining genetic fidelity and the overall stability of biological systems.Furthermore, the application of tautomeric concepts is not limited to the laboratory. In natural processes, tautomerism plays a role in metabolic pathways and enzymatic reactions. Enzymes often rely on the tautomeric forms of substrates to facilitate biochemical transformations. For instance, the enzyme catalase uses the tautomeric change of hydrogen peroxide to convert it into water and oxygen, showcasing the significance of this phenomenon in living organisms.In conclusion, the concept of tautomeric structures is a vital aspect of chemistry that encompasses a range of implications from drug design to molecular biology. By understanding how different forms of a compound can interconvert, chemists and biochemists can better predict reactivity, stability, and biological function. As research continues to explore the nuances of tautomerism, it will undoubtedly uncover new insights that enhance our comprehension of chemical behavior and its impact on life itself. The study of tautomeric compounds not only enriches our knowledge of chemistry but also opens doors to innovative solutions in medicine and biotechnology.

在化学领域，理解tautomeric结构的概念对于掌握某些分子的行为和相互作用至关重要。互变异构现象是指化合物以两种或多种可互转形式存在，这些形式通常通过氢原子的重新定位以及单键和双键的转换来区分。这种不同形式之间的动态平衡可以显著影响化合物的性质和反应性，使其成为有机化学中的一个重要概念。例如，考虑经典的酮-烯醇互变异构。 在这种情况下，酮可以与其相应的烯醇形式处于平衡状态。 酮形式的特征是羰基（C=O），通常比烯醇形式更稳定，后者包含一个氢氧基（-OH）附着在碳碳双键（C=C）上。然而，在某些条件下，例如pH值的变化或催化剂的存在，烯醇形式可能会变得更为普遍。这种转变可能对各种化学反应产生重大影响，包括生物系统中涉及的反应。tautomeric这些形式之间的关系不仅仅是理论概念；它在药物设计和开发中具有实际应用。许多药物化合物依赖于其互变异构形式来表现出所需的生物活性。例如，一些药物被设计用于靶向对底物的互变异构状态敏感的特定酶。理解这些形式之间的平衡可以导致开发出更有效且副作用更少的药物。此外，tautomeric化合物的研究不仅限于简单的有机分子。在生物化学中，DNA和RNA等核酸也可以表现出互变异构现象。核苷酸的互变异构形式可能在DNA复制和转录期间影响碱基配对，如果错误的碱基被纳入，可能导致突变。这突显了互变异构在维持遗传保真度和生物系统整体稳定性方面的重要性。此外，tautomeric概念的应用不限于实验室。在自然过程中，互变异构在代谢途径和酶促反应中发挥作用。酶通常依赖于底物的互变异构形式来促进生化转化。例如，酶催化酶利用氢过氧化物的互变异构变化将其转化为水和氧气，展示了这一现象在生物体内的重要性。总之，tautomeric结构的概念是化学中一个至关重要的方面，涵盖了从药物设计到分子生物学的一系列影响。通过理解化合物的不同形式如何相互转化，化学家和生物化学家可以更好地预测反应性、稳定性和生物功能。随着研究继续探索互变异构的细微差别，它无疑会揭示新的见解，增强我们对化学行为及其对生命本身影响的理解。对tautomeric化合物的研究不仅丰富了我们对化学的知识，还为医学和生物技术中的创新解决方案打开了大门。