lactam

简明释义

[ˈlæktæm][ˈlæktæm]

n. [有化] 内酰胺

英英释义

A lactam is a cyclic amide, which is a compound formed by the reaction of an amino acid and a carboxylic acid, characterized by a nitrogen atom in a ring structure.

内酰胺是一种环状酰胺,是由氨基酸和羧酸反应形成的化合物,其特征是环结构中含有一个氮原子。

单词用法

lactam synthesis

内酰胺合成

lactam bond

内酰胺键

lactamase enzyme

内酰胺酶

lactam formation

内酰胺形成

penicillin lactam

青霉素内酰胺

lactam antibiotics

内酰胺类抗生素

lactam structure

内酰胺结构

lactam resistance

内酰胺抗性

同义词

β-lactam

β-内酰胺

β-lactam antibiotics are widely used to treat bacterial infections.

β-内酰胺抗生素广泛用于治疗细菌感染。

lactam antibiotic

内酰胺抗生素

Lactam compounds are important in medicinal chemistry.

内酰胺化合物在药物化学中很重要。

反义词

lactone

内酯

Lactones are cyclic esters formed from hydroxy acids.

内酯是由羟基酸形成的环状酯。

amine

Amines are derivatives of ammonia and can act as bases.

胺是氨的衍生物,可以作为碱。

例句

1.The invention is suitable for enterprises which take lactam as a raw material to produce high-strength nylon 6.

本发明方法适用于以己内酰胺为原料生产高强度尼龙6轮胎帘子线和工程塑料的企业。

2.The article briefs the source and harm of beta-lactam antibiotic in milk. The article also provides information for improvement on the methods of determination and quality of milk and milk products.

介绍了牛奶中青霉素类抗生素残留的来源、危害,并对在牛奶中常见的青霉素类抗生素的检测方法进行了阐述,对于改进实验方法和提高奶及奶制品质量都有一定的借鉴作用。

3.Head spore Sai Fu sodium molecular structure stabilizes , not being destroyed by beta-lactam enzyme , can not produce resistance to drugs or the resistance to drugs alternating therefore.

头孢噻呋钠分子结构稳定,不被β-内酰胺酶破坏,因此不会产生抗药性或交叉抗药性。

4.The present invention is directed to certain lactam compounds which are useful as neurokinin-1 (NK-1) receptor antagonists, and inhibitors of tachykinin and in particular substance p.

本发明涉及某些内酰胺化合物,其适用作神经激肽- 1 (NK - 1)受体拮抗剂,速激肽特别是P物质抑制剂。

5.The terpolymers of the invention: (a) a vinyl lactam, such as vinyl pyrrolidone or vinyl caprolactam;

发明的三元:(一)一乙烯基酰胺,如聚乙烯吡咯烷酮或乙烯基己内酰胺;

6.The results indicated that b-lactam antibiotics could be identified in glass vials without sample pretreatment.

结果表明,该法无需对样本进行预处理,直接扫描玻璃瓶内样品,即可准确鉴别。

7.The article briefs the source and harm of beta-lactam antibiotic in milk. The article also provides information for improvement on the methods of determination and quality of milk and milk products.

介绍了牛奶中青霉素类抗生素残留的来源、危害,并对在牛奶中常见的青霉素类抗生素的检测方法进行了阐述,对于改进实验方法和提高奶及奶制品质量都有一定的借鉴作用。

8.The mechanism of action of β-lactam antibiotics involves inhibiting cell wall synthesis.

β-内酰胺抗生素的作用机制涉及抑制细胞壁合成。

9.Cefalosporins are a class of antibiotics that contain a β-lactam structure.

头孢菌素是一类含有β-内酰胺结构的抗生素。

10.Researchers are developing new drugs based on the lactam ring to combat resistant bacteria.

研究人员正在开发基于内酰胺环的新药物,以对抗耐药细菌。

11.Some bacteria produce enzymes that can break down lactams, leading to antibiotic resistance.

一些细菌产生能够分解内酰胺的酶,从而导致抗生素耐药性。

12.Penicillin is a well-known antibiotic that contains a β-lactam structure.

青霉素是一种众所周知的抗生素,含有β-内酰胺结构。

作文

Lactams are a class of cyclic amides that play a crucial role in the field of medicinal chemistry. The term ‘lactam’ refers to a specific type of chemical structure that contains a nitrogen atom within a ring, which is derived from amino acids. These compounds are essential in the development of various antibiotics and have significant implications in the treatment of bacterial infections. Understanding the structure and function of lactams is vital for researchers and pharmaceutical companies aiming to design new drugs. The discovery of lactams revolutionized the way we approach bacterial infections. For instance, penicillin, one of the first antibiotics discovered, is a lactam that has saved countless lives since its introduction. The mechanism of action of lactams involves inhibiting the synthesis of bacterial cell walls, which ultimately leads to the death of the bacteria. This unique mechanism highlights the importance of understanding the structural properties of lactams to enhance their efficacy and reduce resistance.In recent years, researchers have focused on modifying the lactam structure to overcome the growing problem of antibiotic resistance. By altering the chemical composition of lactams, scientists can create new derivatives that are more effective against resistant strains of bacteria. This ongoing research is crucial as it addresses the urgent need for new antibiotics in an era where many existing treatments are becoming less effective.Moreover, lactams are not only limited to antibiotics; they also find applications in other areas of medicine. For example, certain lactams are used in the synthesis of anti-cancer drugs, showcasing their versatility in drug development. The ability to modify the lactam structure allows chemists to tailor-make compounds that target specific diseases, thereby improving patient outcomes.In conclusion, lactams are an essential component of modern medicine, particularly in the development of antibiotics and other therapeutic agents. Their unique chemical structure and ability to combat bacterial infections make them invaluable in the ongoing fight against disease. As researchers continue to explore the potential of lactams, it is clear that these compounds will remain at the forefront of pharmaceutical innovation for years to come. Understanding and mastering the intricacies of lactams is not only important for scientists but also for the future of healthcare as we strive to develop new and effective treatments for various ailments.

β-内酰胺是一类环状酰胺,在药物化学领域中发挥着至关重要的作用。术语“β-内酰胺”指的是一种特定类型的化学结构,其中包含一个氮原子在环内,来源于氨基酸。这些化合物在多种抗生素的开发中至关重要,并对细菌感染的治疗具有重要意义。理解β-内酰胺的结构和功能对于研究人员和制药公司设计新药至关重要。β-内酰胺的发现彻底改变了我们对待细菌感染的方式。例如,青霉素是发现的第一种抗生素之一,自引入以来拯救了无数生命。β-内酰胺的作用机制涉及抑制细菌细胞壁的合成,从而最终导致细菌的死亡。这一独特的机制突显了理解β-内酰胺的结构特性的重要性,以增强其有效性并减少耐药性。近年来,研究人员专注于修改β-内酰胺的结构,以克服日益严重的抗生素耐药性问题。通过改变β-内酰胺的化学成分,科学家可以创造出对耐药菌株更有效的新衍生物。这项持续的研究至关重要,因为它解决了在许多现有治疗方法变得不那么有效的时代对新抗生素的迫切需求。此外,β-内酰胺不仅限于抗生素;它们还在医学的其他领域中找到应用。例如,某些β-内酰胺用于抗癌药物的合成,展示了它们在药物开发中的多功能性。修改β-内酰胺的结构使化学家能够量身定制针对特定疾病的化合物,从而改善患者的治疗效果。总之,β-内酰胺是现代医学的重要组成部分,特别是在抗生素和其他治疗剂的开发中。它们独特的化学结构及其对抗细菌感染的能力使其在与疾病的持续斗争中不可或缺。随着研究人员继续探索β-内酰胺的潜力,显然这些化合物将在未来几年继续处于制药创新的前沿。理解和掌握β-内酰胺的复杂性不仅对科学家重要,也对我们努力开发各种疾病的新有效治疗方案的医疗保健未来至关重要。