cephalothin

简明释义

英[ˈsefələˌθɪn]美[ˈsefələθɪn]

n. [药] 先锋霉素；头孢菌素

英英释义

单词用法

同义词

反义词

例句

1.Results:The two strains of Vibrio parahaemolyticus isolates were non-pathogenic, and the strain isolated from small lobster was tolerant to ticarcillin and cephalothin.

结果：所检测的小龙虾和呕吐物中副溶血性弧菌均为不致病性副溶血性弧菌。 小龙虾分离菌株对替卡西林和头孢噻吩耐药。

2.Conclusions SHV-12 ESBL has a highest affinity to ceftazidime and cefotaxime expresses a maximal catalytic efficacy to cephalothin.

结论SHV - 12型esbl对头孢他啶和头孢噻肟具有高的亲和力，而对头孢噻吩有最大的催化效能。

3.This paper makes the emphases on introducing the changing status with the storing time of the changing status with the storing time of the percentage of cephalothin during the course of storing.

本文主要介绍头孢氨苄片在贮存过程中含量随贮存时间的变化情况。

4.This paper makes the emphases on introducing the changing status with the storing time of the changing status with the storing time of the percentage of cephalothin during the course of storing.

本文主要介绍头孢氨苄片在贮存过程中含量随贮存时间的变化情况。

5.Patients with penicillin allergies may be given cephalothin as an alternative.

对青霉素过敏的患者可以选择使用头孢噻吩作为替代药物。

6.In the lab, we tested the effectiveness of cephalothin against various strains of bacteria.

在实验室，我们测试了头孢噻吩对多种细菌株的有效性。

7.The pharmacist explained how to properly administer cephalothin injections.

药剂师解释了如何正确地给药头孢噻吩注射。

8.Research shows that cephalothin is effective in treating skin infections.

研究表明，头孢噻吩对皮肤感染有效。

9.The doctor prescribed cephalothin to treat the patient's bacterial infection.

医生开了头孢噻吩来治疗病人的细菌感染。

作文

In the world of antibiotics, many compounds have played crucial roles in treating infections and saving lives. One such antibiotic is cephalothin, which belongs to the class of drugs known as cephalosporins. Cephalothin is particularly noteworthy for its effectiveness against a variety of Gram-positive bacteria, including staphylococci and streptococci. Developed in the early 1960s, cephalothin was one of the first cephalosporins to be introduced into clinical practice, marking a significant advancement in the field of medicine. The mechanism of action of cephalothin involves inhibiting bacterial cell wall synthesis. This is achieved by binding to penicillin-binding proteins (PBPs) located in the bacterial cell membrane. By interfering with the formation of the cell wall, cephalothin ultimately leads to cell lysis and death, making it a potent weapon against bacterial infections. Despite its effectiveness, the use of cephalothin is not without challenges. One of the primary concerns is the development of antibiotic resistance. Over time, some bacteria have evolved mechanisms to resist the effects of cephalothin, leading to treatment failures. This has prompted healthcare professionals to be cautious in prescribing this antibiotic, reserving it for cases where it is deemed necessary and effective. In addition to its antibacterial properties, cephalothin has also been studied for its pharmacokinetics. It is typically administered intravenously or intramuscularly, allowing for rapid absorption and distribution throughout the body. Understanding the pharmacokinetics of cephalothin is essential for optimizing its therapeutic use and ensuring that patients receive the appropriate dosage for effective treatment. Moreover, cephalothin has been used in various clinical settings, particularly in hospitals where serious infections are prevalent. Its broad spectrum of activity makes it suitable for treating conditions such as pneumonia, skin infections, and urinary tract infections. However, healthcare providers must consider factors such as patient allergies and potential drug interactions before initiating treatment with cephalothin. As we continue to advance our understanding of antibiotics and their role in modern medicine, it is imperative to appreciate the contributions of drugs like cephalothin. While it may not be as widely used today as newer antibiotics, its historical significance and continued relevance in specific clinical scenarios cannot be overlooked. As we face the ongoing challenge of antibiotic resistance, revisiting older antibiotics like cephalothin could provide valuable insights into effective treatment strategies. In conclusion, cephalothin remains an important antibiotic in the medical arsenal. Its ability to combat bacterial infections, combined with the challenges posed by resistance, highlights the need for careful consideration in its use. As research continues to evolve, the legacy of cephalothin serves as a reminder of the importance of antibiotics in preserving human health and combating infectious diseases.

在抗生素的世界中，许多化合物在治疗感染和拯救生命方面发挥了至关重要的作用。一个这样的抗生素是头孢噻吩，它属于称为头孢菌素的药物类别。头孢噻吩尤其以其对多种革兰氏阳性细菌（包括葡萄球菌和链球菌）的有效性而闻名。头孢噻吩于20世纪60年代初开发，是最早引入临床实践的头孢菌素之一，标志着医学领域的一项重大进展。头孢噻吩的作用机制涉及抑制细菌细胞壁的合成。这是通过与位于细菌细胞膜中的青霉素结合蛋白（PBPs）结合来实现的。通过干扰细胞壁的形成，头孢噻吩最终导致细胞溶解和死亡，使其成为对抗细菌感染的强效武器。尽管头孢噻吩具有很强的效果，但其使用并非没有挑战。主要问题之一是抗生素抗药性的产生。随着时间的推移，一些细菌已经进化出抵抗头孢噻吩的机制，导致治疗失败。这促使医疗专业人员在开处方时要谨慎，保留给那些被认为必要且有效的病例。除了抗菌特性外，头孢噻吩的药代动力学也得到了研究。通常通过静脉注射或肌肉注射给药，使其能够迅速吸收并分布到全身。了解头孢噻吩的药代动力学对于优化其治疗使用和确保患者接受适当剂量以有效治疗至关重要。此外，头孢噻吩已在各种临床环境中使用，特别是在严重感染流行的医院中。其广谱活性使其适合治疗肺炎、皮肤感染和尿路感染等情况。然而，医疗提供者必须在开始使用头孢噻吩之前考虑患者过敏和潜在药物相互作用等因素。随着我们继续推进对抗生素及其在现代医学中角色的理解，赞赏像头孢噻吩这样的药物的贡献是至关重要的。尽管今天它的使用可能不如更新的抗生素广泛，但它在特定临床场景中的历史重要性和持续相关性不容忽视。面对抗生素抗药性不断上升的挑战，重新审视像头孢噻吩这样的旧抗生素可能会为有效的治疗策略提供宝贵的见解。总之，头孢噻吩仍然是医疗武器库中的一种重要抗生素。其对抗细菌感染的能力，加上抗药性带来的挑战，突出显示了在使用时需谨慎考虑的必要性。随着研究的不断发展，头孢噻吩的遗产提醒我们抗生素在保护人类健康和对抗传染病方面的重要性。