mercaptopurine

简明释义

英[məˌkæptəʊˈpjʊəriːn]美[mərˌkæptoˈpjʊrin]

n. [有化] 巯嘌呤（尤指6-巯基嘌呤，用以治疗急性白血病）

英英释义

单词用法

同义词

反义词

例句

1.Mercaptopurine has been a standard component of long-term continuing treatment for childhood lymphoblastic leukaemia, whereas 6-thioguanine has been mainly used for intensification courses.

背景6 -巯基嘌呤是治疗儿童淋巴细胞白血病的一种标准的长期维持用药，而6 -硫鸟嘌呤则主要用于强化治疗。

2.A end-column amperometric detection method with capillary electrophoresis for determination of 2-amino-6-mercaptopurine and 8-azaguanine has been established.

采用毛细管电泳-安培检测法建立一种简单、快速、有效的同时分析抗癌药物2-氨基-6-巯基嘌呤和8-氮杂鸟嘌呤的新方法。

3.Immunosuppressants When the condition is difficult to control or it is difficult to reduce your oral steroid dose without relapse, an immunosuppressant such as azathioprine or mercaptopurine is used.

免疫抑制剂时的条件是难以控制或是很困难的，以减少您的口服类固醇剂量，没有复发，免疫抑制剂，如硫唑嘌呤或巯基嘌呤是使用。

4.In this paper, the Electrochemistry behavior of the anticancer drugs 8-azaguanine (8-ag) and 6-mercaptopurine (6-mp) have been studied and the interaction of 8-ag with DNA has been studied too.

本论文用电化学的方法研究了两种抗癌药物——8 -氮鸟嘌呤和6 -巯基嘌呤的电化学性质，同时就其与DNA的相互作用也做了初步的探讨。

5.Immunosuppressants When the condition is difficult to control or it is difficult to reduce your oral steroid dose without relapse, an immunosuppressant such as azathioprine or mercaptopurine is used.

免疫抑制剂时的条件是难以控制或是很困难的，以减少您的口服类固醇剂量，没有复发，免疫抑制剂，如硫唑嘌呤或巯基嘌呤是使用。

6.Patients taking mercaptopurine need regular blood tests to monitor their liver function.

服用巯嘌呤的患者需要定期进行血液检测以监测肝功能。

7.It is important to take mercaptopurine exactly as prescribed by your healthcare provider.

按照医疗提供者的指示准确服用巯嘌呤是很重要的。

8.The doctor prescribed mercaptopurine to help manage the patient's leukemia.

医生开了巯嘌呤来帮助控制患者的白血病。

9.Side effects of mercaptopurine can include nausea and fatigue.

服用巯嘌呤的副作用可能包括恶心和疲劳。

10.Some patients may experience allergic reactions to mercaptopurine.

一些患者可能会对巯嘌呤产生过敏反应。

作文

Mercaptopurine is a medication that plays a crucial role in the treatment of certain types of cancer, particularly leukemia. It is classified as an antimetabolite, which means it interferes with the normal metabolic processes of cells, especially those that are rapidly dividing. This is particularly important in the context of cancer treatment, as cancer cells tend to grow and divide more quickly than normal cells. By inhibiting these processes, mercaptopurine (巯嘌呤) helps to slow down or stop the growth of cancer cells, thereby aiding in the management of the disease.The use of mercaptopurine (巯嘌呤) is not limited to cancer treatment alone; it is also employed in the management of autoimmune diseases such as Crohn's disease and ulcerative colitis. In these conditions, the immune system mistakenly attacks the body's own tissues, leading to inflammation and damage. By suppressing the immune response, mercaptopurine (巯嘌呤) can help reduce inflammation and alleviate symptoms, providing relief to patients suffering from these chronic conditions.One of the significant aspects of mercaptopurine (巯嘌呤) is its mode of action. It is a prodrug, meaning that it is converted into its active form once inside the body. This active form then competes with purines, which are essential building blocks for DNA and RNA synthesis. By disrupting this process, mercaptopurine (巯嘌呤) effectively limits the proliferation of cells that require rapid division, which is a hallmark of both cancerous and inflammatory conditions.However, like many medications, mercaptopurine (巯嘌呤) comes with its own set of potential side effects. Patients may experience nausea, vomiting, and a decrease in blood cell counts, which can lead to increased susceptibility to infections. Therefore, it is essential for healthcare providers to monitor patients closely during treatment. Regular blood tests are often required to ensure that the medication is working effectively while minimizing risks.In conclusion, mercaptopurine (巯嘌呤) serves as a vital tool in the arsenal against cancer and autoimmune diseases. Its ability to inhibit cell division and modulate the immune response makes it a unique and valuable medication. As research continues to evolve, understanding the full scope of mercaptopurine (巯嘌呤) and its applications will undoubtedly enhance treatment protocols and improve patient outcomes. The journey of mercaptopurine (巯嘌呤) from discovery to clinical application underscores the importance of ongoing research in the field of medicine, as we strive to find better and more effective treatments for challenging diseases.