psoralen

简明释义

英[ˈsɔːrəlen]美[ˈpsɔrəlɪn]

n. 补骨脂素

英英释义

单词用法

同义词

反义词

例句

1.Psoralen is the most effective herb for the treatment of vitiligo.

补骨脂是最有效的治疗白癜风的植物。

2.OBJECTIVE to develope and characterize psoralen loaded PLGA nanoparticles for topical formulation, with the final goal of reducing the toxicity and improving the efficacy of PUVA therapy.

目的制备外用的载有补骨脂素的PLGA纳米粒，为临床上改进PUVA疗法降低其毒副作用奠定基础。

3.This paper summarized the antitumor mechanism and application prospect of Psoralen.

文中综述了补骨脂素的抗肿瘤机理及应用研究展望。

4.Its use with Psoralen is beneficial as a home remedy of vitiligo.

将它和补骨脂使用是有益于家庭治疗白癜风的。

5.It was indicated that psoralen had an obvious activation on tyrosinase activity and synergistic effect was significant, but the relationship with concentration was nonlinear.

结果表明，补骨脂素对酪氨酸酶有明显的激活作用，但是不随浓度的增加呈线性变化，与助剂复配的协同效应显著。

6.Recent research has showed that some Chinese herds such as curcumin, cortex phellodendri, psoralen et al, have photodynamic reaction.

近年来研究发现，某些中草药如姜黄素、黄柏、补骨脂素等具有一定的光敏活性作用。

7.CONCLUSION Psoralen loaded PLGA nanospartilcles might be a promising transdermal delivery system in order to improve the efficacy and reduce the side effects in the PUVA therapy.

结论优化条件制备出的补骨脂素皮肤用纳米粒载药系统有可能成为临床上改进补骨素光化学疗法降低其毒副作用的一种新的经皮给药制剂。

8.OBJECTIVE to develope and characterize psoralen loaded PLGA nanoparticles for topical formulation, with the final goal of reducing the toxicity and improving the efficacy of PUVA therapy.

目的制备外用的载有补骨脂素的PLGA纳米粒，为临床上改进PUVA疗法降低其毒副作用奠定基础。

9.Objective To observe the efficacy of psoralen in the treatment of psoriasis vulgaris.

目的观察补骨脂治疗寻常性银屑病的临床疗效及安全性。

10.The dermatologist recommended using psoralen for treating my psoriasis.

皮肤科医生建议我使用psoralen来治疗我的银屑病。

11.Patients should be aware of the side effects associated with psoralen before starting treatment.

患者在开始治疗前应了解与psoralen相关的副作用。

12.The study showed that psoralen is effective in managing eczema symptoms.

研究表明，psoralen对管理湿疹症状有效。

13.After taking psoralen, I noticed a significant improvement in my skin condition.

服用psoralen后，我注意到我的皮肤状况有了显著改善。

14.Phototherapy combined with psoralen can enhance the treatment effects for skin disorders.

与psoralen结合的光疗可以增强皮肤疾病的治疗效果。

作文

Psoralen is a naturally occurring compound that has gained significant attention in the fields of dermatology and phototherapy. It is primarily derived from certain plants, such as the seeds of Psoralea corylifolia, and has been used for centuries in traditional medicine. The primary application of psoralen (补骨脂素) is in the treatment of skin disorders, particularly psoriasis and vitiligo. Psoriasis is a chronic autoimmune condition characterized by the rapid growth of skin cells, leading to scaling and inflammation. Vitiligo, on the other hand, is a condition where the skin loses its pigment, resulting in white patches. Both conditions can have a profound impact on an individual's quality of life, making effective treatments crucial.In recent years, psoralen (补骨脂素) has been utilized in combination with ultraviolet light therapy, a treatment known as PUVA (Psoralen and UVA). This method enhances the effectiveness of UV light in treating these skin disorders. When psoralen (补骨脂素) is applied to the skin or taken orally, it makes the skin more sensitive to UVA light. As the patient is exposed to this light, the psoralen (补骨脂素) interacts with the DNA in the skin cells, leading to changes that can reduce the symptoms of psoriasis and promote repigmentation in vitiligo patients.The mechanism of action of psoralen (补骨脂素) involves the formation of DNA cross-links, which can inhibit the proliferation of rapidly dividing skin cells. This is particularly beneficial in psoriasis, where the overproduction of skin cells is a hallmark of the disease. By slowing down this process, psoralen (补骨脂素) helps to alleviate the thickened plaques associated with psoriasis, leading to smoother skin and reduced inflammation.Despite its benefits, the use of psoralen (补骨脂素) is not without risks. Patients undergoing PUVA therapy must be monitored for potential side effects, which can include nausea, headaches, and an increased risk of skin cancer due to prolonged UV exposure. Therefore, it is essential for individuals considering this treatment to consult with a healthcare professional who can provide guidance based on their specific condition and medical history.Moreover, ongoing research continues to explore the potential applications of psoralen (补骨脂素) beyond dermatological uses. Studies have suggested that it may possess anti-inflammatory and immunomodulatory properties, opening avenues for its use in treating other autoimmune diseases. Additionally, its role in enhancing the efficacy of certain chemotherapeutic agents is being investigated, which could lead to novel cancer treatment strategies.In conclusion, psoralen (补骨脂素) is a versatile compound with significant therapeutic potential, particularly in the realm of skin disorders like psoriasis and vitiligo. Its ability to enhance the effects of UV light therapy has made it a valuable tool in dermatology. However, as with any treatment, it is crucial to weigh the benefits against the risks and to seek professional advice before starting any new therapy. With continued research and understanding of psoralen (补骨脂素), we may unlock even more possibilities for its use in medicine, ultimately improving the lives of those affected by various skin conditions and beyond.

补骨脂素是一种天然存在的化合物，在皮肤病学和光疗领域引起了显著关注。它主要来源于某些植物，如补骨脂的种子，并且在传统医学中已经使用了数百年。psoralen（补骨脂素）的主要应用是在皮肤疾病的治疗中，特别是银屑病和白癜风。银屑病是一种慢性自身免疫性疾病，其特征是皮肤细胞快速生长，导致鳞屑和炎症。另一方面，白癜风是一种皮肤失去色素的疾病，导致白斑。这两种疾病对个人生活质量有深远的影响，因此有效的治疗至关重要。近年来，psoralen（补骨脂素）与紫外光疗法结合使用，形成了一种称为PUVA（补骨脂素和UVA）的治疗方法。这种方法增强了紫外光在治疗这些皮肤疾病中的有效性。当psoralen（补骨脂素）涂抹在皮肤上或口服时，它使皮肤对UVA光更加敏感。当患者暴露于这种光线下时，psoralen（补骨脂素）与皮肤细胞中的DNA相互作用，导致变化，从而减少银屑病的症状并促进白癜风患者的再色素化。psoralen（补骨脂素）的作用机制涉及DNA交联的形成，这可以抑制快速分裂的皮肤细胞的增殖。这对银屑病尤其有益，因为该疾病的标志是皮肤细胞的过度生产。通过减缓这一过程，psoralen（补骨脂素）有助于缓解与银屑病相关的厚板，导致皮肤更平滑，炎症减少。尽管有其好处，使用psoralen（补骨脂素）并非没有风险。接受PUVA治疗的患者必须监测潜在的副作用，包括恶心、头痛以及由于长期暴露于紫外线下而增加的皮肤癌风险。因此，考虑这种治疗的个人必须咨询医疗专业人员，以根据他们的具体情况和病史提供指导。此外，持续的研究继续探索psoralen（补骨脂素）在皮肤病以外的潜在应用。研究表明，它可能具有抗炎和免疫调节特性，为其在其他自身免疫性疾病的治疗中的应用开辟了途径。此外，它在增强某些化疗药物的疗效中的作用也正在研究中，这可能导致新的癌症治疗策略。总之，psoralen（补骨脂素）是一种多功能化合物，具有显著的治疗潜力，特别是在银屑病和白癜风等皮肤疾病领域。它增强紫外光疗法效果的能力使其成为皮肤科的重要工具。然而，像任何治疗一样，权衡益处与风险至关重要，并在开始任何新疗法之前寻求专业建议。随着对psoralen（补骨脂素）的持续研究和理解，我们可能会解锁其在医学中更多的应用可能性，最终改善受各种皮肤疾病和其他疾病影响的人的生活。