pleiotropism

简明释义

英[plaɪˈɒtrəˌpɪzəm]美[plaɪˈɑːtrəˌpɪzəm]

n. [遗] 基因多效性；一因多效

英英释义

单词用法

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例句

1.More than 80% QTLs tended to have pleiotropism or physiological associations.

以上的主效QTL呈现一因多效或生理相关。

2.More than 80% QTLs tended to have pleiotropism or physiological associations.

以上的主效QTL呈现一因多效或生理相关。

3.The concept of pleiotropism is essential in understanding how a single gene can affect multiple traits.

对多效性的理解对于认识单个基因如何影响多个性状至关重要。

4.Understanding pleiotropism helps geneticists predict the potential impact of gene therapy.

理解多效性有助于遗传学家预测基因治疗的潜在影响。

5.In medicine, pleiotropism can explain why certain drugs have side effects that impact various body systems.

在医学中，多效性可以解释为什么某些药物会对不同的身体系统产生副作用。

6.Research on pleiotropism has revealed that some genetic mutations can lead to a range of diseases.

对多效性的研究揭示了一些基因突变可能导致多种疾病。

7.The study of pleiotropism is crucial for developing effective treatments for complex genetic disorders.

对多效性的研究对于开发复杂遗传疾病的有效治疗至关重要。

作文

Pleiotropism is a fascinating concept in genetics that refers to the phenomenon where a single gene influences multiple phenotypic traits. This characteristic can be observed in various organisms, including humans, plants, and animals. Understanding pleiotropism (基因多效性) is crucial for researchers and scientists as it helps explain the complexities of genetic interactions and their implications on health and development.One prominent example of pleiotropism (基因多效性) can be seen in the case of the Marfan syndrome, a genetic disorder caused by mutations in the FBN1 gene. This single gene mutation leads to various symptoms affecting different systems in the body, such as the skeletal system, cardiovascular system, and eyes. Individuals with Marfan syndrome may exhibit tall stature, long limbs, and an increased risk of heart problems. This illustrates how one gene can have widespread effects on multiple body systems, showcasing the essence of pleiotropism (基因多效性).In agriculture, pleiotropism (基因多效性) plays a significant role in crop improvement. Breeders often select for specific traits, such as disease resistance or drought tolerance, but these traits can be influenced by the same genes. For instance, a gene that enhances drought resistance might also affect plant height or yield. Understanding the pleiotropism (基因多效性) of these genes allows breeders to make informed decisions, ensuring that they do not inadvertently select against other desirable traits while trying to enhance one specific characteristic.Moreover, pleiotropism (基因多效性) raises important questions in the field of pharmacogenomics, which studies how genes affect a person's response to drugs. Certain genetic variations can lead to variations in drug metabolism, efficacy, and side effects. A gene that is responsible for metabolizing a particular medication might also influence other biological processes, resulting in unexpected reactions. This complexity highlights the importance of understanding pleiotropism (基因多效性) when developing personalized medicine approaches, as it can significantly impact treatment outcomes.The study of pleiotropism (基因多效性) also extends to evolutionary biology, where it provides insights into how traits evolve over time. When a gene affects multiple traits, natural selection can act on those traits simultaneously. This can lead to evolutionary advantages or disadvantages depending on the environment. For example, a trait that improves survival in one context might also have negative consequences in another. Understanding pleiotropism (基因多效性) helps explain the intricate balance of evolutionary pressures that shape the diversity of life we see today.In conclusion, pleiotropism (基因多效性) is a key concept in genetics that underscores the interconnectedness of traits influenced by single genes. Its implications span across various fields, including medicine, agriculture, and evolutionary biology. As research continues to uncover the complexities of genetic interactions, the significance of pleiotropism (基因多效性) will undoubtedly grow, providing deeper insights into the mechanisms that govern life and its diversity.