adenoviral

简明释义

英[ˌædəˈnaɪvərəl]美[ˌædəˈnaɪvərəl]

腺病毒的

英英释义

单词用法

同义词

反义词

例句

1.Objective: To observe the transduction efficiency of adenoviral-mediated gene transfer in human breast cancer cells and the effect of viral transduction on the growth of the cancer cells.

目的：观察腺病毒介导的基因转移在乳腺癌细胞的转导效率及腺病毒转导对细胞生长的影响。

2.The method taught herein functions to offset pre-existing immunity through the delivery of the protein or antigen by a cocktail of at least two adenoviral serotypes.

本文所述方法的作用是通过至少两种腺病毒血清型混合物送递蛋白质或抗原，以抵消已有的免疫力。

3.AIM: to construct the recombinant adenoviral vector carrying antisense RNA to chemokine receptors CCR5 and CXCR4 and to obtain recombinant adenovirus, which will be used to resist HIV 1 infection.

目的：构建趋化因子受体c CR 5,CXCR4双靶区反义rna重组载体并获取重组腺病毒以用于抗hiv 1基因治疗的研究。

4.Objective To study the feasibility of adenoviral transduction of Herceptin complete antibody gene and its effect on Her2 over expressing cancer.

目的探讨应用基因治疗方法表达完全抗体的可行性及其对肿瘤的治疗作用。

5.Objective: to study the inhibitory effects on gastric cancer by adenoviral transduction of mouse endostatin gene.

目的：研究腺病毒介导的鼠内皮抑素基因对胃癌的治疗作用。

6.Objective: to clone the human and murine origin RANTES genes and construct the adenoviral expression vectors.

目的：克隆人和小鼠的活化t细胞表达与分泌调节基因(RANTES基因)并分别构建腺病毒表达载体。

7.Scientists are exploring adenoviral 腺病毒的 vaccines to combat various infectious diseases.

科学家们正在探索腺病毒的疫苗以对抗各种传染病。

8.The research focused on the use of adenoviral 腺病毒的 vectors for gene therapy.

该研究集中在使用腺病毒的载体进行基因治疗。

9.A clinical trial is testing an adenoviral 腺病毒的 vector for delivering therapeutic genes.

一项临床试验正在测试一种用于递送治疗基因的腺病毒的载体。

10.The adenoviral 腺病毒的 vector system is known for its ability to transduce a wide range of cell types.

众所周知，腺病毒的载体系统能够转导多种细胞类型。

11.The adenoviral 腺病毒的 infection can lead to respiratory illnesses in children.

感染腺病毒的可以导致儿童呼吸道疾病。

作文

In recent years, the field of gene therapy has gained significant attention due to its potential to treat various genetic disorders. One of the most promising vectors used in this field is the adenovirus, which is often referred to as adenoviral. This term describes anything related to adenoviruses, a group of viruses that can cause a range of illnesses in humans. The use of adenoviral vectors in gene therapy is particularly noteworthy because they can efficiently deliver therapeutic genes into human cells.Adenoviruses are non-enveloped viruses with a double-stranded DNA genome. They were initially discovered as pathogens responsible for respiratory infections, but researchers quickly recognized their potential as tools for gene delivery. The adenoviral vector system has several advantages, including a broad host range and the ability to transduce both dividing and non-dividing cells. This makes them ideal candidates for delivering genes to a variety of tissues in the body.One of the key applications of adenoviral vectors is in the treatment of cancer. By engineering these viruses to carry tumor-suppressing genes or genes that induce apoptosis (programmed cell death) in cancer cells, scientists aim to create targeted therapies that can specifically attack tumors while sparing healthy tissue. Clinical trials have shown promising results, demonstrating that adenoviral therapies can effectively reduce tumor size and improve patient outcomes.Moreover, adenoviral vectors have been utilized in vaccine development. For instance, during the COVID-19 pandemic, some vaccines were based on adenoviral technology. These vaccines work by using a modified version of an adenovirus to deliver the genetic instructions for producing a harmless piece of the virus that causes COVID-19. This process stimulates the immune system to recognize and fight the actual virus if encountered in the future.Despite their many advantages, the use of adenoviral vectors is not without challenges. One major concern is the immune response that these vectors can elicit. Since adenoviruses are common pathogens, many individuals have pre-existing immunity to them, which can limit the effectiveness of adenoviral therapies. Researchers are actively exploring ways to overcome this issue, such as using less common serotypes of adenoviruses or employing techniques to evade the immune system.In conclusion, the term adenoviral encompasses a wide range of applications in gene therapy and vaccine development. As research continues to evolve, the potential for adenoviral vectors to revolutionize the treatment of various diseases becomes increasingly apparent. The ongoing exploration of their capabilities, coupled with advancements in genetic engineering, holds great promise for the future of medicine. Understanding the implications of adenoviral technology will be crucial for both researchers and healthcare professionals as we move toward more effective and personalized treatments for patients around the world.

近年来，基因治疗领域因其治疗各种遗传疾病的潜力而受到广泛关注。用于该领域的最有前途的载体之一是腺病毒，它通常被称为adenoviral。这个术语描述了与腺病毒相关的任何事物，这是一组可以在人类中引起多种疾病的病毒。adenoviral载体在基因治疗中的使用尤其值得注意，因为它们可以有效地将治疗基因递送到人类细胞中。腺病毒是无包膜的病毒，具有双链DNA基因组。它们最初被发现为引起呼吸道感染的病原体，但研究人员很快认识到它们作为基因递送工具的潜力。adenoviral载体系统具有多个优点，包括广泛的宿主范围和能够转导分裂和非分裂细胞。这使得它们成为将基因递送到体内各种组织的理想候选者。adenoviral载体的一个关键应用是在癌症治疗中。通过工程这些病毒以携带肿瘤抑制基因或诱导癌细胞凋亡（程序性细胞死亡）的基因，科学家们旨在创造能够特异性攻击肿瘤的靶向疗法，同时保护健康组织。临床试验显示出令人鼓舞的结果，证明adenoviral疗法能够有效减少肿瘤大小并改善患者预后。此外，adenoviral载体已被用于疫苗开发。例如，在COVID-19大流行期间，一些疫苗基于adenoviral技术。这些疫苗通过使用改造过的腺病毒递送产生无害的COVID-19病毒部分的遗传指令。这一过程刺激免疫系统识别并在未来遇到实际病毒时进行抵抗。尽管有许多优点，但使用adenoviral载体并非没有挑战。一个主要的担忧是这些载体可能引发的免疫反应。由于腺病毒是常见的病原体，许多个体对其已有免疫，这可能限制adenoviral疗法的有效性。研究人员正在积极探索克服这一问题的方法，例如使用不太常见的腺病毒血清型或采用规避免疫系统的技术。总之，adenoviral一词涵盖了基因治疗和疫苗开发中的广泛应用。随着研究的持续发展，adenoviral载体在革命性治疗各种疾病方面的潜力变得越来越明显。对其能力的持续探索，加上基因工程的进步，为未来医学的希望提供了巨大的承诺。理解adenoviral技术的含义对于研究人员和医疗专业人员来说至关重要，因为我们朝着为全球患者提供更有效和个性化的治疗迈进。