valproic

简明释义

英[vælˈprəʊɪk]美[vælˈproʊɪk]

丙戊酸

英英释义

单词用法

同义词

反义词

例句

1.Valproic acid (VPA) is often used to treat seizure disorder and mania as a mood stabilizer.

丙戊酸(VPA)常被用于治疗癫痫和躁狂症，是一种情绪稳定药物。

2.OBJECTIVE To investigate the association between valproic acid (VAP) plasma concentration at steady state (Css) and CYP2C19 gene polymorphisms for better individualized medication.

目的：寻找丙戊酸药物浓度与CYP2C19基因多态性的关系，以便临床根据患者的基因型进行个体化给药。

3.Taking L-carnitine supplements may prevent any deficiency and may also reduce the side effects of valproic acid.

以L -肉碱的补充防止任何缺陷，也可能降低丙戊酸的副作用。

4.Valproic acid (VPA) is a compound of fatty acid and a commonly used anti-epileptic drug.

丙戊酸为一侧链脂肪酸类化合物，是临床治疗多种类型癫痫的一线药物。

5.OBJECTIVE: to observe the factors that influence the fluctuation of serum concentrations of valproic acid and to improve the effectiveness and usefulness of monitoring the serum concentration.

前言：目的：探讨影响丙戊酸钠血药浓度波动的因素，提高丙戊酸钠血药浓度检测的有效性及可利用性。

6.METHODS 156 epileptic outpatients received valproic acid as monopharmacy or in combination with either the antiepileptic drug were monitored during their clinical routine care.

方法对156例接受丙戊酸单药或联合用药治疗的门诊癫痫患者进行血药浓度监测。

7.The patient was prescribed valproic 丙戊酸 acid to manage their seizures.

患者被开处方使用valproic丙戊酸来控制癫痫发作。

8.Doctors often recommend valproic 丙戊酸 for bipolar disorder treatment.

医生通常推荐使用valproic丙戊酸治疗双相情感障碍。

9.Before starting valproic 丙戊酸 therapy, liver function tests are essential.

在开始使用valproic丙戊酸治疗之前，进行肝功能检查是必要的。

10.The use of valproic 丙戊酸 can lead to weight gain in some individuals.

使用valproic丙戊酸可能导致某些人群体重增加。

11.Patients taking valproic 丙戊酸 should be monitored for potential side effects.

服用valproic丙戊酸的患者应监测潜在的副作用。

作文

Valproic acid, often referred to simply as valproic (丙戊酸), is a medication primarily used to treat epilepsy and bipolar disorder. It is also used to prevent migraine headaches. The discovery of valproic (丙戊酸) in the late 1960s marked a significant advancement in the field of neurology and psychiatry. Before its introduction, patients suffering from seizure disorders had limited options, many of which came with severe side effects. Valproic (丙戊酸) offered a new hope for these individuals, as it proved to be effective in controlling seizures with a more favorable side effect profile.The mechanism of action of valproic (丙戊酸) is not entirely understood, but it is believed to increase the availability of gamma-aminobutyric acid (GABA) in the brain. GABA is an inhibitory neurotransmitter that helps to calm neural activity. By enhancing GABA levels, valproic (丙戊酸) can stabilize mood and reduce seizure frequency, making it a versatile treatment option.In addition to its use in epilepsy, valproic (丙戊酸) has gained recognition for its effectiveness in treating manic episodes associated with bipolar disorder. Patients often report significant improvements in mood stability when using valproic (丙戊酸) as part of their treatment regimen. However, like all medications, it is not without risks. Some patients may experience side effects such as gastrointestinal disturbances, weight gain, or even liver toxicity. Therefore, regular monitoring by healthcare professionals is essential for those prescribed valproic (丙戊酸).The versatility of valproic (丙戊酸) extends beyond its primary uses. Researchers have explored its potential applications in other conditions, including post-traumatic stress disorder (PTSD) and various neurodegenerative diseases. Preliminary studies suggest that valproic (丙戊酸) may have neuroprotective properties, which could make it a valuable tool in the treatment of conditions characterized by neuronal damage.Despite its benefits, the use of valproic (丙戊酸) requires careful consideration, particularly during pregnancy. Studies have shown that exposure to valproic (丙戊酸) during pregnancy can increase the risk of congenital malformations and developmental delays in infants. As a result, healthcare providers must weigh the risks and benefits when prescribing this medication to pregnant women.In conclusion, valproic (丙戊酸) is a crucial medication in the management of epilepsy and bipolar disorder, offering relief to many patients who struggle with these conditions. Its ability to enhance GABA levels in the brain contributes to its effectiveness in stabilizing mood and controlling seizures. While it has proven to be a valuable treatment option, ongoing research continues to uncover its potential in other areas of medicine. As we gain a deeper understanding of valproic (丙戊酸) and its effects, we can better serve patients in need of effective and safe therapeutic options.

丙戊酸，通常简单称为valproic（丙戊酸），是一种主要用于治疗癫痫和双相情感障碍的药物。它也用于预防偏头痛。valproic（丙戊酸）在20世纪60年代末的发现标志着神经学和精神病学领域的重要进展。在其引入之前，患有癫痫发作障碍的患者选择有限，许多选择伴随严重的副作用。valproic（丙戊酸）为这些人提供了新的希望，因为它被证明在控制癫痫发作方面有效，并且副作用更为温和。valproic（丙戊酸）的作用机制尚不完全清楚，但据信它可以增加大脑中γ-氨基丁酸（GABA）的可用性。GABA是一种抑制性神经递质，有助于平静神经活动。通过增强GABA水平，valproic（丙戊酸）可以稳定情绪并减少癫痫发作频率，使其成为一种多用途的治疗选择。除了用于癫痫外，valproic（丙戊酸）因其在治疗双相情感障碍相关的躁狂发作中的有效性而受到认可。患者在使用valproic（丙戊酸）作为治疗方案的一部分时，通常报告情绪稳定显著改善。然而，与所有药物一样，它并非没有风险。一些患者可能会经历如胃肠道不适、体重增加甚至肝毒性等副作用。因此，对于那些被处方valproic（丙戊酸）的人，定期的医疗监测是至关重要的。valproic（丙戊酸）的多功能性超出了其主要用途。研究人员探索了它在其他疾病中的潜在应用，包括创伤后应激障碍（PTSD）和各种神经退行性疾病。初步研究表明，valproic（丙戊酸）可能具有神经保护特性，这可能使其成为治疗以神经元损伤为特征的疾病的宝贵工具。尽管有其益处，但在怀孕期间使用valproic（丙戊酸）需要仔细考虑。研究表明，在怀孕期间接触valproic（丙戊酸）可能会增加婴儿先天畸形和发育延迟的风险。因此，医疗提供者在给怀孕女性开处方时必须权衡风险和收益。总之，valproic（丙戊酸）是管理癫痫和双相情感障碍的重要药物，为许多与这些疾病斗争的患者提供了缓解。它增强大脑中GABA水平的能力有助于其在稳定情绪和控制癫痫发作方面的有效性。虽然它已被证明是一种宝贵的治疗选择，但持续的研究继续揭示其在医学其他领域的潜力。随着我们对valproic（丙戊酸）及其影响的深入了解，我们可以更好地为需要有效和安全治疗选择的患者服务。