methylase

简明释义

英[ˈmeθɪˌleɪz]美[ˈmeθɪlez]

n. [生化] 甲基化酶

英英释义

单词用法

同义词

反义词

例句

1.The invention belongs to the technical field of plant gene engineering, and more particularly relates to a paddy rice histone demethyl methylase gene, coded protein and the application thereof.

本发明属于植物基因工程技术领域，具体涉及一种水稻组蛋白去甲基化酶基因及其编码蛋白与应用。

2.The invention belongs to the technical field of plant gene engineering, and more particularly relates to a paddy rice histone demethyl methylase gene, coded protein and the application thereof.

本发明属于植物基因工程技术领域，具体涉及一种水稻组蛋白去甲基化酶基因及其编码蛋白与应用。

3.Specific methylase enzymes were isolated from M. mycoides and used to methylate the M. mycoides genome isolated from yeast.

丝状支原体中分离出特异性的甲基酶，进而用该酶甲基化酵母中提取出的丝状支原体基因组。

4.Understanding the function of methylase is essential for genetic engineering.

理解甲基转移酶的功能对基因工程至关重要。

5.Researchers discovered a new type of methylase that affects gene expression.

研究人员发现了一种新的甲基转移酶，它影响基因表达。

6.The study focused on the substrate specificity of methylase enzymes.

这项研究集中在甲基转移酶酶的底物特异性上。

7.Inhibition of methylase can lead to changes in cellular processes.

抑制甲基转移酶可能导致细胞过程的变化。

8.The enzyme methylase plays a crucial role in DNA modification.

酶甲基转移酶在DNA修饰中起着至关重要的作用。

作文

In the realm of molecular biology, enzymes play a crucial role in facilitating various biochemical processes. One such enzyme is methylase, which is responsible for the transfer of methyl groups to specific substrates. This process is known as methylation, and it is essential for regulating gene expression, DNA repair, and the synthesis of certain biomolecules. Understanding the function of methylase can provide significant insights into genetic regulation and cellular function.Methylation is a fundamental biological mechanism that involves adding a methyl group (CH3) to DNA or proteins, thereby influencing their activity without altering the underlying DNA sequence. The action of methylase is particularly important in the context of epigenetics, where changes in gene expression can occur without changes to the DNA itself. For instance, when methylase adds methyl groups to the promoter region of a gene, it can inhibit the binding of transcription factors, effectively silencing the gene. This process is vital for normal development and cellular differentiation, allowing cells to express only the genes necessary for their specific functions.Moreover, the role of methylase extends beyond gene regulation. It is also involved in the repair of damaged DNA. When DNA is exposed to environmental stressors or replication errors, methylase can help restore its integrity by adding methyl groups that signal repair mechanisms. This highlights the enzyme's importance not only in maintaining genetic stability but also in preventing diseases such as cancer, where improper methylation patterns can lead to uncontrolled cell growth.In addition to its biological significance, methylase has garnered interest in the field of biotechnology. Scientists are exploring how to manipulate methylase activity to develop new therapeutic strategies for diseases linked to abnormal methylation patterns. For example, drugs that inhibit or enhance methylase activity could potentially be used to treat various cancers or genetic disorders. By understanding how methylase functions, researchers can design targeted therapies that correct methylation imbalances and restore normal gene expression.Furthermore, the study of methylase has implications for agriculture and food production. Genetic modifications that involve methylase can lead to crops with improved traits, such as increased resistance to pests or enhanced nutritional content. By controlling the expression of specific genes through methylation, scientists hope to create sustainable agricultural practices that can meet the growing global food demand.In conclusion, methylase is a pivotal enzyme in the world of molecular biology, playing a key role in gene regulation, DNA repair, and biotechnological applications. Its ability to modify the methylation status of DNA and proteins makes it an essential player in cellular processes and offers exciting possibilities for future research and therapeutic interventions. As we continue to unravel the complexities of gene regulation and cellular function, the study of methylase will undoubtedly remain at the forefront of scientific inquiry, paving the way for new discoveries in health, agriculture, and beyond.

在分子生物学领域，酶在促进各种生化过程中发挥着至关重要的作用。其中一种酶是methylase，它负责将甲基转移到特定底物上。这个过程被称为甲基化，对于调节基因表达、DNA修复和某些生物分子的合成至关重要。理解methylase的功能可以为我们提供关于遗传调控和细胞功能的重要见解。甲基化是一种基本的生物机制，涉及将甲基（CH3）添加到DNA或蛋白质上，从而影响其活性，而不改变基础的DNA序列。methylase的作用在表观遗传学的背景下尤为重要，在这种情况下，基因表达的变化可以在不改变DNA本身的情况下发生。例如，当methylase将甲基添加到基因的启动子区域时，它可以抑制转录因子的结合，有效地沉默该基因。这个过程对于正常发育和细胞分化至关重要，使细胞能够仅表达其特定功能所需的基因。此外，methylase的作用不仅限于基因调控。它还参与修复受损的DNA。当DNA暴露于环境压力或复制错误时，methylase可以通过添加甲基来帮助恢复其完整性，这会信号修复机制。这突显了该酶在维持遗传稳定性以及预防疾病（如癌症）方面的重要性，因为不当的甲基化模式可能导致细胞生长失控。除了其生物学意义外，methylase在生物技术领域也引起了人们的关注。科学家们正在探索如何操纵methylase的活性，以开发针对与异常甲基化模式相关的疾病的新治疗策略。例如，抑制或增强methylase活性的药物可能用于治疗各种癌症或遗传疾病。通过理解methylase的功能，研究人员可以设计针对性的疗法，以纠正甲基化失衡并恢复正常的基因表达。此外，methylase的研究对农业和食品生产也有影响。涉及methylase的基因改造可以导致具有改善特性的作物，例如增加对害虫的抵抗力或增强营养成分。通过控制特定基因的表达，科学家希望创造可持续的农业实践，以满足全球日益增长的食品需求。总之，methylase是在分子生物学世界中一个关键的酶，在基因调控、DNA修复和生物技术应用中发挥着重要作用。它修改DNA和蛋白质的甲基化状态的能力使其成为细胞过程中的重要参与者，并为未来的研究和治疗干预提供了令人兴奋的可能性。随着我们继续揭示基因调控和细胞功能的复杂性，methylase的研究无疑将继续处于科学探究的前沿，为健康、农业等领域的新发现铺平道路。