Lethal Dose 50

简明释义

半致死量

英英释义

Lethal Dose 50 (LD50) is a standard measurement used in toxicology to indicate the dose of a substance that is lethal to 50% of a test population, typically expressed in milligrams of substance per kilogram of body weight.

致死剂量50(LD50)是毒理学中使用的标准测量,表示对测试人群中50%致命的物质剂量,通常以每千克体重的毫克数表示。

例句

1.Researchers are conducting tests to determine the Lethal Dose 50 (致死剂量50) for various pharmaceuticals.

研究人员正在进行测试,以确定各种药物的Lethal Dose 50 (致死剂量50)。

2.The study revealed that the Lethal Dose 50 (致死剂量50) of the new pesticide was significantly lower than previously thought.

研究显示,新农药的Lethal Dose 50 (致死剂量50) 明显低于之前的预期。

3.In toxicology, understanding the Lethal Dose 50 (致死剂量50) helps in assessing the safety of chemicals.

在毒理学中,了解Lethal Dose 50 (致死剂量50) 有助于评估化学品的安全性。

4.Safety regulations often require knowledge of the Lethal Dose 50 (致死剂量50) before a substance can be approved for use.

安全法规通常要求在批准物质使用之前了解其Lethal Dose 50 (致死剂量50)。

5.The Lethal Dose 50 (致死剂量50) of this toxin is critical for developing antidotes.

这种毒素的Lethal Dose 50 (致死剂量50) 对于开发解毒剂至关重要。

作文

The term Lethal Dose 50 refers to the amount of a substance that is sufficient to cause death in 50% of a tested population. This measurement is crucial in toxicology and pharmacology, as it helps researchers and medical professionals understand the potential dangers of various substances, including drugs, chemicals, and environmental toxins. By determining the Lethal Dose 50, scientists can assess the relative toxicity of different compounds and establish safety guidelines for their use.In the field of medicine, understanding the Lethal Dose 50 is essential for ensuring patient safety. For instance, when developing new medications, researchers conduct extensive testing to determine the appropriate dosages that will be effective without being harmful. If a drug has a low Lethal Dose 50, it means that only a small amount can lead to serious health risks or fatality. This information is vital for physicians prescribing medications, as they must balance efficacy with safety to avoid adverse effects.Moreover, the concept of Lethal Dose 50 also extends beyond pharmaceuticals. In environmental science, it is used to evaluate the toxicity of pollutants and hazardous materials. For example, when assessing the impact of a chemical spill, environmental scientists may use the Lethal Dose 50 to predict the potential harm to wildlife and ecosystems. Understanding how much of a substance can be lethal to half of a population allows for better risk assessments and more effective remediation strategies.The determination of Lethal Dose 50 involves rigorous experimentation, often using animal models to simulate human responses. While this practice raises ethical concerns regarding animal welfare, it remains a standard method for evaluating toxicity. Researchers must carefully design their studies to ensure accurate results while minimizing harm to the animals involved. Additionally, advancements in technology are leading to alternative methods, such as computer modeling and in vitro testing, which may reduce the reliance on animal testing in the future.Public awareness of the Lethal Dose 50 is also important, especially when it comes to consumer products. Many household items, such as cleaning supplies and pesticides, contain chemicals that can be dangerous if misused. Education on the potential risks associated with these substances can empower individuals to make safer choices and handle products responsibly. For instance, labeling products with information about their Lethal Dose 50 could help consumers understand the risks involved and encourage them to follow safety instructions carefully.In conclusion, the concept of Lethal Dose 50 is a fundamental aspect of toxicology that plays a significant role in various fields, including medicine, environmental science, and public safety. By measuring the amount of a substance that can be lethal to half of a population, researchers can assess risks and develop guidelines to protect human health and the environment. As our understanding of toxicity evolves, so too will our approaches to studying and mitigating the dangers posed by harmful substances. It is imperative that both professionals and the general public remain informed about the implications of Lethal Dose 50 to promote safety and well-being in our communities.

术语Lethal Dose 50指的是足以导致50%受试人群死亡的物质量。这个测量在毒理学和药理学中至关重要,因为它帮助研究人员和医疗专业人员理解各种物质(包括药物、化学品和环境毒素)的潜在危险。通过确定Lethal Dose 50,科学家可以评估不同化合物的相对毒性,并建立其使用的安全指南。在医学领域,理解Lethal Dose 50对确保患者安全至关重要。例如,在开发新药时,研究人员会进行广泛的测试,以确定有效但不危害健康的适当剂量。如果一种药物的Lethal Dose 50较低,这意味着只有少量就可能导致严重健康风险或致命。这一信息对于开处方的医生至关重要,因为他们必须在疗效与安全之间取得平衡,以避免不良反应。此外,Lethal Dose 50的概念还超越了药物。在环境科学中,它用于评估污染物和危险材料的毒性。例如,在评估化学泄漏的影响时,环境科学家可能会使用Lethal Dose 50来预测对野生动物和生态系统的潜在危害。了解多少物质对一半人群是致命的,可以更好地进行风险评估和更有效的修复策略。确定Lethal Dose 50涉及严格的实验,通常使用动物模型模拟人类反应。虽然这种做法引发了关于动物福利的伦理问题,但它仍然是评估毒性的标准方法。研究人员必须仔细设计他们的研究,以确保准确的结果,同时最小化对参与动物的伤害。此外,技术的进步正在导致替代方法,如计算机建模和体外测试,这可能减少未来对动物测试的依赖。公众对Lethal Dose 50的认识也很重要,特别是在消费品方面。许多家居用品,如清洁剂和杀虫剂,含有如果误用可能会危险的化学品。对这些物质潜在风险的教育可以使个人做出更安全的选择,负责任地处理产品。例如,用有关其Lethal Dose 50的信息标记产品,可以帮助消费者理解所涉及的风险,并鼓励他们认真遵循安全说明。总之,Lethal Dose 50的概念是毒理学的一个基本方面,在医学、环境科学和公共安全等多个领域发挥着重要作用。通过测量足以对一半人群致命的物质量,研究人员可以评估风险并制定保护人类健康和环境的指南。随着我们对毒性的理解不断发展,我们对研究和减轻有害物质危害的方式也将不断演变。专业人员和公众都必须保持对Lethal Dose 50影响的了解,以促进我们社区的安全和福祉。

相关单词

lethal

lethal详解:怎么读、什么意思、用法

dose

dose详解:怎么读、什么意思、用法