mitomycin

简明释义

英[ˌmaɪtəʊˈmaɪsɪn]美[ˌmaɪtəˈmaɪsɪn]

n. [微][药] 丝裂霉素

英英释义

单词用法

同义词

反义词

例句

1.ObjectiveTo investigate the sustained release property of chemotherapy by fibrin glue enwrapping mitomycin (MMC/FG).

探讨丝裂霉素纤维蛋白胶凝胶（MMC/FG）化疗的缓释特性。

2.Objective: the aim of the present research is to study the selectivity of Mitomycin on human umbilical vein endothelial cells (HUVEC) function and cell migration and the mechanism was also discussed.

目的：观察丝裂霉素对人脐静脉血管内皮细胞(HUVEC)作用的选择性和细胞迁移能力的影响及机制研究。

3.Objective to observe the effect of mitomycin-C (MMC) and removable suture in refractory glaucoma.

目的观察小梁切除术中应用丝裂霉素c (MMC)联合可拆式缝线的治疗效果和并发症。

4.OBJECTIVE To review the applications of mitomycin C in ophthalmology.

目的总结丝裂霉素C在眼科领域的应用现状。

5.ObjectiveTo study the role of mitomycin C(MMC) and hyaluronic acid (HA) on the proliferations of normal and photorefractive keratectomy(PRK) rabbit corneal fibroblasts.

目的了解丝裂霉素C（MMC）及透明质酸（HA）对准分子激光屈光性角膜切削术（PRK）术后及正常兔角膜成纤维细胞增殖的影响。

6.Method 32 eyes of 31 cases suffering uneasily glaucoma were treated with silica gel inserted on superior ciliary cavae and the use of mitomycin C.

方法31例32眼难治青光眼采用睫状体上腔装置硅橡胶条合并使用丝裂霉素C治疗。

7.The mechanism of action of mitomycin involves DNA cross-linking.

丝裂霉素的作用机制涉及DNA交联。

8.Before administering mitomycin, the doctor explained the potential risks to the patient.

在给患者注射丝裂霉素之前，医生向患者解释了潜在风险。

9.Patients receiving mitomycin may experience side effects such as nausea and fatigue.

接受丝裂霉素治疗的患者可能会经历恶心和疲劳等副作用。

10.The oncologist prescribed mitomycin for the treatment of bladder cancer.

肿瘤科医生开了丝裂霉素用于膀胱癌的治疗。

11.In clinical trials, mitomycin showed promising results against certain types of tumors.

在临床试验中，丝裂霉素对某些类型的肿瘤显示出良好的效果。

作文

Mitomycin is a potent antibiotic that has garnered attention in the medical field for its unique properties and applications. Originally derived from the bacterium *Streptomyces caespitosus*, mitomycin (米托霉素) is primarily known for its effectiveness in treating various types of cancers, particularly bladder cancer, breast cancer, and gastric cancer. The mechanism of action of mitomycin is quite fascinating; it works by inhibiting DNA synthesis, which ultimately leads to cell death in rapidly dividing cancer cells. This characteristic makes it a valuable tool in chemotherapy regimens, especially when used in combination with other agents.One of the remarkable aspects of mitomycin is its ability to target hypoxic tumor cells. Tumors often have regions that are poorly oxygenated, making them more resistant to conventional therapies. However, mitomycin can be activated under low oxygen conditions, allowing it to selectively kill these hard-to-treat cells. This selectivity provides a significant advantage in improving the overall effectiveness of cancer treatments.Despite its benefits, the use of mitomycin is not without risks. Patients undergoing treatment may experience a range of side effects, including nausea, vomiting, and myelosuppression, which is a decrease in bone marrow activity leading to reduced blood cell production. As a result, careful monitoring and supportive care are essential during treatment to manage these potential complications.In addition to its oncological applications, mitomycin has also been explored in other areas of medicine. For instance, it has been utilized in the field of ophthalmology for its ability to reduce scarring during glaucoma surgery. By applying mitomycin to the surgical site, surgeons can minimize the formation of scar tissue, thereby improving the success rate of the procedure. This off-label use highlights the versatility of mitomycin beyond traditional cancer therapies.Research continues to uncover new potential uses for mitomycin. Scientists are investigating its efficacy in combination with immunotherapies and targeted therapies, hoping to enhance treatment outcomes for patients with various malignancies. Furthermore, ongoing studies aim to better understand the pharmacokinetics and pharmacodynamics of mitomycin, which could lead to optimized dosing strategies and reduced side effects.In conclusion, mitomycin (米托霉素) represents a significant advancement in cancer treatment and has potential applications in other medical fields as well. Its unique mechanism of action and ability to target resistant tumor cells make it a valuable asset in the fight against cancer. However, healthcare providers must remain vigilant regarding the associated risks and side effects. As research progresses, we can anticipate even more innovative uses for mitomycin, further solidifying its role in modern medicine.

米托霉素是一种强效的抗生素，在医学领域因其独特的特性和应用而受到关注。米托霉素最初是从*Streptomyces caespitosus*细菌中提取的，主要以其在治疗各种癌症（特别是膀胱癌、乳腺癌和胃癌）方面的有效性而闻名。米托霉素的作用机制相当迷人；它通过抑制DNA合成来发挥作用，最终导致快速分裂的癌细胞死亡。这一特性使得它成为化疗方案中的宝贵工具，尤其是在与其他药物联合使用时。米托霉素的一个显著特点是它能够靶向缺氧肿瘤细胞。肿瘤通常有氧气供应不足的区域，使其对传统疗法更具抵抗力。然而，米托霉素可以在低氧条件下被激活，从而选择性地杀死这些难以治疗的细胞。这种选择性为提高癌症治疗的整体有效性提供了显著优势。尽管米托霉素有其好处，但其使用并非没有风险。接受治疗的患者可能会经历一系列副作用，包括恶心、呕吐和骨髓抑制，即骨髓活动减少导致血细胞生成减少。因此，在治疗期间需要仔细监测和支持护理，以管理这些潜在并发症。除了在肿瘤学中的应用外，米托霉素还在医学其他领域中得到了探索。例如，由于其能在青光眼手术中减少瘢痕形成，因此在眼科领域得到了应用。通过将米托霉素应用于手术部位，外科医生可以最小化瘢痕组织的形成，从而提高手术的成功率。这种非标签用途突显了米托霉素在传统癌症治疗之外的多样性。研究继续揭示米托霉素的新潜在用途。科学家们正在研究其与免疫疗法和靶向疗法联合应用的有效性，希望增强患者在各种恶性肿瘤中的治疗效果。此外，正在进行的研究旨在更好地理解米托霉素的药代动力学和药效学，这可能导致优化的剂量策略和减少副作用。总之，米托霉素（米托霉素）代表了癌症治疗的重要进展，并且在其他医学领域也具有潜在应用。其独特的作用机制和靶向耐药肿瘤细胞的能力使其成为与癌症斗争中的宝贵资产。然而，医疗提供者必须保持警惕，关注相关的风险和副作用。随着研究的进展，我们可以期待米托霉素有更多创新的用途，进一步巩固其在现代医学中的角色。