plasmin

简明释义

英[ˈplæzmɪn]美[ˈplæzmɪn]

n. 胞浆素；[生化] 血纤维蛋白溶酶

英英释义

单词用法

同义词

反义词

例句

1.Plasmin is the main protease to break down and dissolve thrombus.

胞浆素是消除和分解血栓的主要蛋白酶。

2.This is primarily accomplished by the generation of plasmin, which breaks down fibrin and interferes with its polymerization.

这主要是通过纤维蛋白溶酶的生成，分解纤维蛋白和干扰其聚合。

3.In this paper the best conditions of activity of plasmin were studied.

研究了赤子爱胜蚓纤溶酶活性的提高条件及酶的最适作用条件。

4.After digestion by plasmin, the collagen fibrillar network was destructed.

经过纤溶酶消化后，玻璃体胶原纤维的网状结构破坏。

5.Objective To reveal the fibrillar network in vitreous and the effect of plasmin on this network.

目的观察玻璃体胶原纤维的空间结构及纤溶酶对其空间结构的影响。

6.B. Nattokinase enhances plasmin through active pro-urokinase (endogenous).

纳豆激酶通过活性尿激酶原(内生)增强胞浆素。

7.Objective To observe the clinical and fibrinolytic effect of Urokinase (UK) therapy in the acute cerebral infarction, and alteration of D-dimer concentrations and plasmin activity.

目的观察尿激酶(UK)治疗急性脑梗死的疗效及血浆纤溶酶的活性变化。

8.Conclusion: the study indicated that it was related to disturbance or fibrinolysis coagulation system in the patients with HAPC and plasmin capsules were valuable in prevention and treatment of HAPC.

结论：高原红细胞增多症患者存在纤溶抑制功能的亢进及凝血与纤溶系统的紊乱，溶栓胶囊对高原红细胞增多症具有明显的防治效果。

9.The activation of plasmin is a key step in the fibrinolytic pathway.

plasmin（纤溶酶）的激活是纤维蛋白溶解途径中的关键步骤。

10.Elevated levels of plasmin can indicate an increased risk of bleeding disorders.

升高的plasmin（纤溶酶）水平可能表明出血性疾病的风险增加。

11.The role of plasmin in the breakdown of fibrin clots is crucial for wound healing.

在纤维蛋白血块的分解中，plasmin（纤溶酶）的作用对伤口愈合至关重要。

12.Inhibitors of plasmin are being developed to control excessive bleeding during surgeries.

正在开发plasmin（纤溶酶）的抑制剂，以控制手术期间的过度出血。

13.Researchers are studying how plasmin can be used to improve thrombolytic therapy.

研究人员正在研究如何利用plasmin（纤溶酶）来改善溶栓治疗。

作文

In the field of biochemistry, understanding the various proteins and enzymes that play crucial roles in our body is essential. One such important enzyme is plasmin, which is primarily involved in the process of fibrinolysis. Fibrinolysis is the breakdown of fibrin in blood clots, a vital process that helps to maintain normal blood flow and prevent excessive clotting. The formation of blood clots is a necessary response to injury, but once the tissue has healed, it is equally important to remove these clots to restore proper circulation. This is where plasmin comes into play. Plasmin is derived from its inactive precursor, plasminogen, which is synthesized in the liver and released into the bloodstream. When a blood clot forms, plasminogen is incorporated into the clot. The conversion of plasminogen to plasmin is triggered by several factors, including tissue plasminogen activator (tPA) and urokinase. These activators cleave plasminogen, allowing it to transform into the active enzyme plasmin. Once activated, plasmin breaks down fibrin, effectively dissolving the blood clot. The activity of plasmin is tightly regulated within the body. Excessive fibrinolysis can lead to conditions such as hemorrhage, while insufficient activity can result in thrombosis, where blood clots form excessively. Therefore, the balance between the formation and breakdown of clots is critical for maintaining hemostasis, and plasmin is a key player in this delicate balance. In addition to its role in fibrinolysis, plasmin has been implicated in other physiological processes, including tissue remodeling and inflammation. For instance, during wound healing, plasmin not only helps to clear away clots but also facilitates the migration of cells necessary for tissue repair. Furthermore, plasmin can activate certain growth factors and matrix metalloproteinases, which are essential for tissue regeneration. Research on plasmin has significant clinical implications. For instance, understanding how to modulate plasmin activity can lead to better treatments for thrombotic diseases, such as deep vein thrombosis or pulmonary embolism. Additionally, enhancing plasmin activity may be beneficial in conditions where excessive clotting occurs. On the other hand, inhibiting plasmin could be a therapeutic strategy in situations where bleeding is a concern. In conclusion, plasmin is a vital enzyme in our body that plays a crucial role in the regulation of blood clotting. Its ability to dissolve fibrin clots ensures that our circulatory system functions smoothly after an injury. Moreover, plasmin is involved in various physiological processes beyond fibrinolysis, making it an important target for medical research. As we continue to unravel the complexities of plasmin and its functions, we will likely uncover new therapeutic avenues for managing a range of cardiovascular and inflammatory conditions.

在生物化学领域，理解和掌握体内各种蛋白质和酶的关键作用是至关重要的。其中一个重要的酶是纤溶酶，它主要参与纤维蛋白溶解过程。纤维蛋白溶解是血液凝块中纤维蛋白的分解，这一过程对维持正常的血流和防止过度凝血至关重要。血块的形成是对损伤的必要反应，但一旦组织愈合，清除这些血块同样重要，以恢复正常的血液循环。这就是纤溶酶发挥作用的地方。纤溶酶源自其无活性的前体纤溶酶原，纤溶酶原在肝脏合成并释放到血液中。当血块形成时，纤溶酶原被纳入血块中。纤溶酶原转化为纤溶酶的过程是由多种因素触发的，包括组织纤溶酶原激活剂（tPA）和尿激酶。这些激活剂切割纤溶酶原，使其转变为活性酶纤溶酶。一旦被激活，纤溶酶就会分解纤维蛋白，有效地溶解血块。纤溶酶的活性在体内受到严格调控。过度的纤溶作用可能导致出血等疾病，而不足的活性则可能导致血栓形成，即血块过度形成。因此，凝块的形成与分解之间的平衡对于维持止血至关重要，而纤溶酶正是这一微妙平衡中的重要角色。除了在纤维蛋白溶解中的作用外，纤溶酶还与其他生理过程有关，包括组织重塑和炎症。例如，在伤口愈合过程中，纤溶酶不仅帮助清除血块，还促进了修复组织所需细胞的迁移。此外，纤溶酶可以激活某些生长因子和基质金属蛋白酶，这些都是组织再生所必需的。对纤溶酶的研究具有重要的临床意义。例如，了解如何调节纤溶酶的活性可以导致更好的治疗血栓性疾病的方法，如深静脉血栓或肺栓塞。此外，增强纤溶酶的活性可能对过度凝血的情况有益。另一方面，抑制纤溶酶可能是处理出血问题的治疗策略。总之，纤溶酶是我们体内一种重要的酶，在血液凝固的调节中发挥着关键作用。它溶解纤维蛋白血块的能力确保了我们在受伤后循环系统的顺利运作。此外，纤溶酶还参与了超出纤维蛋白溶解的各种生理过程，使其成为医学研究的重要目标。随着我们继续揭示纤溶酶及其功能的复杂性，我们可能会发现新的治疗途径，以应对一系列心血管和炎症相关疾病。