aromatase

简明释义

英[/əˈroʊməˌteɪs/]美[/əˈroʊməˌteɪs/]

n. 芳香化酶；芳香酶

英英释义

单词用法

同义词

反义词

例句

1.The much higher cost of the aromatase inhibitors has been an issue for some women.

对一些女性来说，芳香酶抑制剂高的多的花费一直是一个问题。

2.Aromatase is a new target enzyme for designing anti breast cancer drugs.

芳香酶是研究抗乳腺癌药物的新靶酶。

3.The new aromatase inhibitors are highly selective and very well tolerated by patients clinically.

新一代芳香酶抑制剂的选择性高，耐受性好，目前在临床上得到广泛的应用。

4.It was also unclear why the aromatase inhibitors were causing these aches and pains.

也不清楚为什么芳香酶抑制剂会导致这些疼痛和痛苦。

5.In fact, the analysis showed that 132 patients must be treated with an aromatase inhibitor before one cardiovascular problem occurs.

实际上，这个分析显示132名患者在一个心血管疾病出现前，必须用芳香酶抑制剂治疗。

6.An expert who worked on the landmark ATAC study that first showed the effectiveness of aromatase inhibitors disagrees.

工作于首次显示芳香酶抑制剂有效性的标志atac研究的一个专家不同意。

7.An acid found in pomegranates appears to block aromatase, an enzyme that converts androgen to estrogen - a hormone that plays a role in the development of breast cancer.

研究人员在石榴中发现了一种可抑制芳香酶活性的酸性化合物。芳香酶会把雄激素转换为雌激素，而雌激素会增加女性罹患乳腺癌的风险。

8.Hormone therapy includes tamoxifen and aromatase inhibitors.

激素治疗包括三苯氧胺和芳香酶抑制剂。

9.Men with low testosterone may have elevated aromatase activity.

睾酮水平低的男性可能有升高的芳香化酶活性。

10.The enzyme aromatase is crucial for the conversion of androgens to estrogens.

酶芳香化酶对雄激素转化为雌激素至关重要。

11.Research shows that high levels of aromatase may be linked to certain types of cancer.

研究表明，高水平的芳香化酶可能与某些类型的癌症有关。

12.Inhibitors of aromatase are often used in breast cancer treatment.

抑制芳香化酶的药物常用于乳腺癌治疗。

13.The aromatase gene plays a significant role in hormone regulation.

芳香化酶基因在激素调节中发挥重要作用。

作文

Aromatase is an essential enzyme in the human body that plays a critical role in the synthesis of estrogens from androgens. Understanding the function of aromatase (芳香化酶) is crucial for both medical research and therapeutic applications, particularly in the fields of oncology and endocrinology. In recent years, the significance of aromatase has been highlighted in various studies focusing on hormone-dependent cancers, such as breast cancer. This condition often involves elevated levels of estrogen, which can stimulate the growth of cancerous cells. Therefore, inhibiting aromatase activity has become a common therapeutic strategy to reduce estrogen production and slow down tumor progression.The mechanism of action for aromatase involves converting testosterone and androstenedione into estradiol and estrone, respectively. This conversion process is vital for maintaining hormonal balance within the body. However, when the regulation of aromatase is disrupted, it can lead to various health issues, including obesity, infertility, and hormone-sensitive cancers. For instance, postmenopausal women often experience increased aromatase activity, which contributes to higher estrogen levels, further complicating their health status.In clinical settings, aromatase inhibitors are frequently prescribed to treat patients with estrogen receptor-positive breast cancer. These drugs work by blocking the action of aromatase, thereby lowering estrogen levels in the body. Research has shown that the use of aromatase inhibitors can significantly improve survival rates among women diagnosed with this type of cancer. However, like any medication, they come with potential side effects, including hot flashes, joint pain, and an increased risk of osteoporosis. Therefore, healthcare providers must carefully evaluate the risks and benefits before recommending these treatments.Moreover, the study of aromatase extends beyond cancer treatment. It is also relevant in understanding other conditions linked to hormonal imbalances. For example, polycystic ovary syndrome (PCOS) is associated with elevated androgen levels and altered aromatase activity, leading to irregular menstrual cycles and fertility issues. By exploring the relationship between aromatase and various endocrine disorders, researchers can develop more targeted therapies aimed at restoring hormonal balance and improving patient outcomes.In conclusion, the enzyme aromatase (芳香化酶) serves a fundamental role in estrogen biosynthesis, influencing numerous physiological processes. Its importance in cancer treatment and other hormonal disorders cannot be overstated. Continued research into aromatase will undoubtedly yield new insights into its functions and pave the way for innovative therapeutic strategies. As our understanding of this enzyme deepens, we may discover more effective ways to manage hormone-related diseases, ultimately improving the quality of life for many individuals affected by these conditions.