dapsone

简明释义

英[ˈdæpˌsəʊn]美[ˈdæpˌsoʊn]

n. [有化] 氨苯砜，二氨二苯砜

英英释义

单词用法

同义词

反义词

例句

1.Dapsone is the first choice for its therapy.

氨苯砜是治疗的首选药物。

2.Spironolactone and codeine can cause drug hypersensitivity syndrome, while dapsone and vancomycin can cause dapsone syndrome and red-man syndrome respectively.

螺内酯、可待因等可引起药物超敏反应综合征、氨苯砜和万古霉素等分别可引起氨苯砜综合征及红人综合征。

3.Objective: To detect resistant stains of Mycobacterium leprae to dapsone (DDS) and rifampicin (RFP) and to understand the relationship between relapse and drug resistance.

目的：检测麻风菌的氨苯砜、利福平耐药基因，以了解复发与耐药的关系。

4.Dapsone gel was particularly effective against inflammatory acne lesions, they point out, with decreases in inflammatory lesions evident as early as 2 weeks after beginning treatment.

用氨苯砜凝胶治疗炎性痤疮是非常有效的，他们指出，治疗2周后炎性损害就有明显下降。

5.Dapsone gel was particularly effective against inflammatory acne lesions, they point out, with decreases in inflammatory lesions evident as early as 2 weeks after beginning treatment.

用氨苯砜凝胶治疗炎性痤疮是非常有效的，他们指出，治疗2周后炎性损害就有明显下降。

6.In the 1960s, M. leprae started to develop resistance to dapsone, the world’s only known anti-leprosy drug at that time.

在1960年代，麻风杆菌开始对世界上当时唯一已知的抗麻风药物氨苯砜形成抗药性。

7.For thosewith negative smears, dapsone and rifampin for one year is the standard of carein the United States.

如果是阴性，服用氨苯砜与利福平1年是标准疗法。

8.Although leprosy was treated differently in the past, the first breakthrough occurred in the 1940s with the development of the drug dapsone, which arrested the disease.

旧时对麻风的治疗很不同。在1940年代出现了第一次突破，当时研制出了可抑制该病的药物氨苯砜。

9.The pharmacist explained how to take dapsone properly.

药剂师解释了如何正确服用dapsone。

10.Patients taking dapsone should have regular blood tests to monitor their health.

服用dapsone的患者应该定期进行血液检查以监测他们的健康状况。

11.In some cases, dapsone is used to treat dermatitis herpetiformis.

在某些情况下，dapsone用于治疗皮肤疱疹性皮炎。

12.The doctor prescribed dapsone for the treatment of leprosy.

医生开了dapsone用于麻风的治疗。

13.Side effects of dapsone can include headache and nausea.

服用dapsone的副作用可能包括头痛和恶心。

作文

Dapsone is a medication that has been used for several decades to treat various diseases, particularly leprosy and certain types of pneumonia. It belongs to a class of drugs known as sulfone antibiotics, which work by inhibiting the growth of bacteria. One of the remarkable aspects of dapsone is its effectiveness against Mycobacterium leprae, the bacterium responsible for leprosy. This disease, although rare in many parts of the world today, still affects thousands of people, particularly in developing countries. The use of dapsone has significantly reduced the incidence of leprosy and has allowed many patients to lead normal lives after treatment.In addition to its role in treating leprosy, dapsone is also effective against other bacterial infections, such as those caused by Pneumocystis jirovecii, which can lead to pneumonia in immunocompromised individuals, particularly those with HIV/AIDS. The ability of dapsone to target these specific pathogens makes it an essential tool in the medical field, especially in managing opportunistic infections.The mechanism of action of dapsone involves the inhibition of folate synthesis in bacteria. By blocking the utilization of para-aminobenzoic acid (PABA), dapsone prevents bacteria from synthesizing folate, which is crucial for their growth and reproduction. This targeted approach minimizes the impact on human cells, making dapsone relatively safe for use in patients.However, like all medications, dapsone is not without its side effects. Some patients may experience adverse reactions, including hemolytic anemia, skin rashes, and gastrointestinal disturbances. It is crucial for healthcare providers to monitor patients closely during treatment with dapsone to manage any potential complications effectively. Regular blood tests are often recommended to check for any signs of hemolysis, especially in individuals with glucose-6-phosphate dehydrogenase (G6PD) deficiency, who are at higher risk for severe reactions.Despite these concerns, the benefits of dapsone in treating serious infections cannot be overstated. In the context of public health, dapsone has played a vital role in controlling the spread of leprosy and improving the quality of life for affected individuals. The World Health Organization (WHO) has endorsed the use of dapsone as part of multi-drug therapy for leprosy, emphasizing its importance in global health initiatives.In recent years, research has also explored the potential of dapsone in treating other conditions, such as dermatitis herpetiformis and certain autoimmune disorders. This expanding range of applications highlights the versatility of dapsone as a therapeutic agent. As scientists continue to investigate its mechanisms and potential new uses, dapsone remains a valuable part of the pharmacological arsenal.In conclusion, dapsone is a significant medication with a rich history in treating infectious diseases. Its effectiveness, particularly against leprosy and pneumonia, underscores its importance in modern medicine. While awareness of potential side effects is necessary, the overall impact of dapsone on public health and individual patient outcomes is profoundly positive. As we advance our understanding of this drug, it is essential to recognize its contributions to global health and the ongoing need for effective treatments against bacterial infections.

达普松是一种已使用数十年的药物，主要用于治疗各种疾病，特别是麻风和某些类型的肺炎。它属于磺胺类抗生素，这类药物通过抑制细菌的生长来发挥作用。dapsone的一个显著特点是它对麻风分枝杆菌（Mycobacterium leprae）的有效性，这种细菌是导致麻风的罪魁祸首。尽管在今天的许多地方这种疾病相对罕见，但仍然影响着成千上万的人，尤其是在发展中国家。dapsone的使用显著减少了麻风的发生率，并使许多患者在治疗后能够过上正常的生活。除了在治疗麻风方面的作用外，dapsone在治疗由肺孢子虫（Pneumocystis jirovecii）引起的其他细菌感染方面也有效，这种感染可能在免疫受损个体中导致肺炎，特别是那些感染了HIV/AIDS的人。dapsone能够针对这些特定病原体，使其成为医学领域的重要工具，尤其是在管理机会性感染方面。dapsone的作用机制涉及抑制细菌中的叶酸合成。通过阻止对对氨基苯甲酸（PABA）的利用，dapsone防止细菌合成叶酸，而叶酸对它们的生长和繁殖至关重要。这种靶向方法最小化了对人类细胞的影响，使得dapsone在患者中相对安全。然而，像所有药物一样，dapsone并非没有副作用。一些患者可能会出现不良反应，包括溶血性贫血、皮疹和胃肠道不适。在使用dapsone治疗期间，医疗提供者密切监测患者以有效管理潜在并发症至关重要。通常建议定期进行血液检查，以检测任何溶血迹象，尤其是在具有葡萄糖-6-磷酸脱氢酶（G6PD）缺乏症的个体中，他们面临严重反应的更高风险。尽管存在这些问题，dapsone在治疗严重感染方面的益处不可低估。在公共卫生的背景下，dapsone在控制麻风传播和改善受影响个体的生活质量方面发挥了至关重要的作用。世界卫生组织（WHO）已认可将dapsone作为麻风多药联合治疗的一部分，强调了它在全球健康倡议中的重要性。近年来，研究还探索了dapsone在治疗其他疾病（如皮肤天疱疮和某些自身免疫性疾病）中的潜力。这一应用范围的扩展凸显了dapsone作为治疗剂的多功能性。随着科学家们继续研究其机制和潜在的新用途，dapsone仍然是药物武器库中宝贵的一部分。总之，dapsone是一种具有丰富历史的显著药物，用于治疗传染病。它的有效性，尤其是在麻风和肺炎方面，突显了它在现代医学中的重要性。虽然了解潜在副作用是必要的，但dapsone对公共卫生和个体患者结果的整体影响是深远的。随着我们对该药物理解的深入，认识到它对全球健康的贡献和对抗细菌感染的有效治疗的持续需求至关重要。