amyloid

简明释义

[ˈæmɪlɔɪd][ˈæmɪˌlɔɪd]

n. 淀粉样蛋白,类淀粉的复杂蛋白质;淀粉性变样

adj. 类淀粉的

英英释义

A type of protein that can form abnormal aggregates in the body, often associated with diseases such as Alzheimer's and other amyloidosis conditions.

一种可以在体内形成异常聚集的蛋白质,通常与阿尔茨海默病和其他淀粉样变病相关。

单词用法

amyloid plaques

淀粉样斑块

amyloid fibrils

淀粉样纤维

amyloid deposition

淀粉样沉积

amyloid beta

淀粉样β蛋白

systemic amyloidosis

全身性淀粉样变

localized amyloidosis

局部淀粉样变

同义词

protein aggregate

蛋白质聚集体

Amyloid proteins can form protein aggregates that are associated with various diseases.

淀粉样蛋白可以形成与多种疾病相关的蛋白质聚集体。

fibril

纤维

Fibrils are often found in the brains of patients with Alzheimer's disease.

在阿尔茨海默病患者的大脑中常常发现纤维。

plaques

斑块

The presence of amyloid plaques is a hallmark of neurodegenerative disorders.

淀粉样斑块的存在是神经退行性疾病的标志。

反义词

soluble protein

可溶性蛋白

Soluble proteins are essential for various biological functions.

可溶性蛋白对各种生物功能至关重要。

normal protein

正常蛋白

Normal proteins maintain cellular homeostasis.

正常蛋白维持细胞的稳态。

例句

1.For the past two decades, therefore, most attention has been given to developing drugs that will remove amyloid plaques from an affected brain.

因此过去20年,注意力一直集中在研发那些能将淀粉样蛋白斑从被感染的大脑中除掉的药物。

2.The study sheds light on how insulin interacts with amyloid, a toxic protein found in Alzheimer's.

这项研究揭示了阿尔兹·海默病患者中发现的淀粉和胰岛素怎样互相作用。

3.The disease begins, they believe, when for still unknown genetic and other reasons, the brain starts to churn out amyloid.

他们相信,疾病发生的初期,虽仍有未知的基因及其他原因在作祟,但脑部已经有大量的类乙型蛋白产生。

4.The severity of amyloidosis depends on which organs the amyloid deposits affect.

淀粉样变的严重性依赖于淀粉样蛋白沉积在哪个器官。

5.People with the disease get plaques in their brains made up of a small protein called amyloid-beta, which clumps together and disrupts brain signals.

得了这种病的人大脑里面的血小板形成一种叫做淀粉样蛋白的蛋白质,这种蛋白质聚集在一起打乱了大脑发出的信号。

6.LEHRER: Your book talks about a new technique that allows doctors to image amyloid plaques in the brain.

LEHRER:你的书介绍了一种新技术,医生可以成像脑中的淀粉样蛋白斑块。

7.A key aspect of Alzheimer's is sticky clumps of an abnormal protein in the brain called beta amyloid plaques.

阿尔兹·海默氏症主要是由于脑部聚集结块的异常蛋白质,名为be ta淀粉状蛋白斑。

8.Amyloid buildup often affects the kidneys, damaging their filtering system.

沉积在肾脏,则损害滤过系统。

9.The presence of amyloid 淀粉样蛋白 deposits can lead to various forms of dementia.

存在的淀粉样蛋白沉积可能导致多种形式的痴呆症。

10.Doctors are studying how amyloid 淀粉样蛋白 affects heart function in patients with cardiac amyloidosis.

医生正在研究淀粉样蛋白如何影响心脏淀粉样变患者的心脏功能。

11.Autopsy results showed significant amyloid 淀粉样蛋白 buildup in the patient's brain.

尸检结果显示患者大脑中有显著的淀粉样蛋白积聚。

12.A new drug is being tested to reduce the levels of amyloid 淀粉样蛋白 in the brain.

一种新药正在测试,以降低大脑中淀粉样蛋白的水平。

13.Researchers found that the accumulation of amyloid 淀粉样蛋白 plaques in the brain is a hallmark of Alzheimer's disease.

研究人员发现,大脑中积累的淀粉样蛋白斑块是阿尔茨海默病的一个标志。

作文

Amyloidosis is a rare but serious condition that arises when the body produces an abnormal protein called amyloid. This protein can accumulate in various organs and tissues, disrupting their normal function. The term amyloid (淀粉样蛋白) refers to a group of proteins that misfold and aggregate, forming deposits that can lead to organ damage. Understanding amyloid (淀粉样蛋白) is crucial for both medical professionals and patients, as it plays a significant role in several diseases, including Alzheimer's disease, where it forms plaques in the brain.The accumulation of amyloid (淀粉样蛋白) can occur in different parts of the body, affecting organs such as the heart, kidneys, liver, and nervous system. In the heart, for instance, amyloid (淀粉样蛋白) deposits can lead to restrictive cardiomyopathy, a condition that inhibits the heart's ability to pump blood effectively. Similarly, when amyloid (淀粉样蛋白) accumulates in the kidneys, it can cause nephrotic syndrome, leading to protein loss in urine and swelling in various parts of the body.One of the most well-known conditions associated with amyloid (淀粉样蛋白) is Alzheimer's disease, a neurodegenerative disorder characterized by cognitive decline and memory loss. In Alzheimer's, the buildup of amyloid (淀粉样蛋白) plaques disrupts communication between neurons, ultimately leading to cell death. This has led researchers to explore therapies that target amyloid (淀粉样蛋白) accumulation as a potential treatment strategy.Diagnosing conditions related to amyloid (淀粉样蛋白) often involves imaging studies and biopsies. For example, a biopsy of affected tissue can reveal the presence of amyloid (淀粉样蛋白) deposits, confirming a diagnosis of amyloidosis. Blood tests can also help identify abnormal levels of proteins associated with amyloid (淀粉样蛋白) production.Treatment options for amyloid (淀粉样蛋白) disorders vary depending on the type and severity of the condition. In some cases, chemotherapy may be used to reduce the production of the abnormal proteins. Other treatments may focus on managing symptoms and supporting affected organs. For instance, patients with cardiac involvement may require medications to manage heart failure symptoms.In conclusion, understanding amyloid (淀粉样蛋白) and its implications is vital for addressing various health issues. As research progresses, new therapies targeting amyloid (淀粉样蛋白) accumulation are being developed, offering hope for those affected by related diseases. Increased awareness and early diagnosis can significantly improve patient outcomes, making it essential for individuals to recognize the signs and seek medical advice if they suspect any related conditions.

淀粉样变性是一种罕见但严重的疾病,发生在身体产生一种异常蛋白质——淀粉样蛋白时。该蛋白质会在各种器官和组织中积聚,干扰其正常功能。术语amyloid(淀粉样蛋白)指的是一组错误折叠并聚集的蛋白质,形成沉积物,导致器官损害。理解amyloid(淀粉样蛋白)对医疗专业人员和患者至关重要,因为它在多种疾病中发挥着重要作用,包括阿尔茨海默病,在这种情况下,它在大脑中形成斑块。amyloid(淀粉样蛋白)的积累可以发生在身体的不同部位,影响心脏、肾脏、肝脏和神经系统等器官。例如,在心脏中,amyloid(淀粉样蛋白)沉积可能导致限制性心肌病,这种情况妨碍心脏有效泵血。同样,当amyloid(淀粉样蛋白)在肾脏中积聚时,它可能导致肾病综合症,导致尿液中蛋白质丧失和身体各部位肿胀。与amyloid(淀粉样蛋白)相关的最著名的疾病之一是阿尔茨海默病,这是一种以认知衰退和记忆丧失为特征的神经退行性疾病。在阿尔茨海默病中,amyloid(淀粉样蛋白)斑块的积聚干扰神经元之间的通信,最终导致细胞死亡。这促使研究人员探索针对amyloid(淀粉样蛋白)积累的治疗方法作为潜在的治疗策略。诊断与amyloid(淀粉样蛋白)相关的疾病通常涉及影像学检查和活检。例如,受影响组织的活检可以揭示amyloid(淀粉样蛋白)沉积的存在,从而确认淀粉样变性的诊断。血液测试也可以帮助识别与amyloid(淀粉样蛋白)生产相关的异常蛋白水平。针对amyloid(淀粉样蛋白)疾病的治疗选择因疾病的类型和严重程度而异。在某些情况下,可能使用化疗来减少异常蛋白的产生。其他治疗可能侧重于管理症状和支持受影响的器官。例如,心脏受累的患者可能需要药物来管理心力衰竭症状。总之,理解amyloid(淀粉样蛋白)及其影响对于解决各种健康问题至关重要。随着研究的进展,针对amyloid(淀粉样蛋白)积累的新疗法正在开发中,为那些受到相关疾病影响的人们带来了希望。提高意识和早期诊断可以显著改善患者的结果,使个人认识到症状并在怀疑任何相关疾病时寻求医疗建议变得至关重要。