phosphoryl

简明释义

英[ˈfɑs.fər.ɪl]美[ˈfɑs.fər.ɪl]

n. 磷酰基

英英释义

单词用法

同义词

反义词

例句

1.The Synthesis of l-acyl-4-phosphoryl Thiosemicarbazides and Their Heterocyclic Derivatives of 1, 3, 4-oxadiazoles.

取代酰基- 4 -磷酰基氨基硫脲及其1,3,4 -恶二唑杂环衍生物的合成。

2.The chiral HMPA analogues 1 and 2 were prepared in high yield by nucleophilic substitution between the chiral secondary amine and phosphoryl chloride.

以磷酰氯为原料通过与手性仲胺的亲核取代反应高产率地合成了手性HMPA类似物。

3.Phosphoenolpyruvate (PEP) is one of the two phosphoryl group donors in the synthesis of ATP during glycolysis.

磷酸烯醇式丙酮酸(pep)是糖酵解中合成atp的两种磷酸基的供体之一。

4.Only N-phosphoryl serine and threonine methyl esters were catalyzed by imidazole, A new type of pentacoordinate phosphorus intermediate was proposed.

反应机理推测为丝、苏氨酸的侧链基团羟基在咪唑的存在下亲核进攻磷原子形成五配位中间体。

5.PKC activity was measured with phosphoryl abevacuation .

磷基转移法测定PKC活性变化。

6.The chiral HMPA analogues 1 and 2 were prepared in high yield by nucleophilic substitution between the chiral secondary amine and phosphoryl chloride.

以磷酰氯为原料通过与手性仲胺的亲核取代反应高产率地合成了手性HMPA类似物。

7.The chiral HMPA analogues were prepared in high yield by nucleophilic substitution between the chiral secondary amine and phosphoryl chloride.

通过磷酰氯与手性仲胺的亲核取代反应高产率地合成了手性HMPA 类似物。

8.The invention relates to a phosphoryl carboxylic acid propofol ester derivative which has the general formula (I).

一种磷酰基羧酸丙泊酚酯衍生物，具有通式（I）。

9.The study focused on how phosphoryl modification affects enzyme activity.

该研究集中于磷酸基团修饰如何影响酶活性。

10.The enzyme transfers a phosphoryl group to the substrate during the reaction.

在反应过程中，酶将一个磷酸基团转移到底物上。

11.The signaling pathway is activated by the phosphoryl group addition.

信号通路通过添加磷酸基团而被激活。

12.Phosphorylation of proteins often involves the addition of a phosphoryl group.

蛋白质的磷酸化通常涉及添加一个磷酸基团。

13.In metabolic pathways, the transfer of phosphoryl groups is crucial for energy production.

在代谢途径中，磷酸基团的转移对能量产生至关重要。

作文

Phosphorylation is a crucial biochemical process that involves the addition of a phosphate group to a molecule, typically a protein. This process plays a vital role in regulating various cellular functions, including metabolism, signal transduction, and cell division. One of the key components in this process is the molecule known as phosphoryl（磷酸基）, which serves as the actual donor of the phosphate group. Understanding the role of phosphoryl（磷酸基） in phosphorylation can provide insights into how cells communicate and respond to their environment.The mechanism of phosphorylation usually begins with the enzyme called a kinase, which transfers a phosphate group from a high-energy donor molecule, such as ATP (adenosine triphosphate), to a specific amino acid residue in a target protein. The phosphate group is often derived from a molecule containing phosphoryl（磷酸基）, which is essential for the phosphorylation process. This modification can alter the protein's function, activity, or location within the cell, thereby influencing cellular behavior.For instance, when a protein is phosphorylated by the addition of a phosphoryl（磷酸基） group, it may change its conformation, allowing it to interact with other proteins or molecules. This interaction can initiate signaling cascades that result in various physiological responses. In this way, the phosphoryl（磷酸基） group acts as a molecular switch, turning on or off specific pathways that are critical for cell survival and function.In addition to kinases, another class of enzymes called phosphatases can remove phosphate groups from proteins, reversing the effects of phosphorylation. This dynamic balance between phosphorylation and dephosphorylation is crucial for maintaining homeostasis within cells. Disruptions in this balance can lead to various diseases, including cancer, diabetes, and neurodegenerative disorders. Therefore, understanding the role of phosphoryl（磷酸基） in these processes can have significant implications for medical research and therapeutic interventions.Moreover, the presence of phosphoryl（磷酸基） groups can also affect the interaction of proteins with DNA. For example, transcription factors that are phosphorylated may exhibit enhanced or reduced binding affinity to specific gene promoters, thereby regulating gene expression. This regulatory mechanism highlights the importance of phosphoryl（磷酸基） in controlling not just protein function but also genetic activity.In conclusion, the study of phosphoryl（磷酸基） and its role in phosphorylation is fundamental to our understanding of cellular processes. As research continues to uncover the complexities of phosphorylation, it becomes increasingly clear that phosphoryl（磷酸基） is not merely a chemical group but a pivotal player in the intricate network of cellular communication. By exploring the mechanisms and effects of phosphorylation, scientists can gain deeper insights into health and disease, paving the way for innovative treatments and therapies that target these essential biochemical pathways.

磷酸化是一个关键的生化过程，涉及将磷酸基团添加到分子上，通常是蛋白质。这个过程在调节各种细胞功能中发挥着重要作用，包括代谢、信号转导和细胞分裂。这个过程中一个关键的成分是被称为phosphoryl（磷酸基）的分子，它作为磷酸基团的实际供体。理解phosphoryl（磷酸基）在磷酸化中的作用可以提供关于细胞如何与环境沟通和响应的见解。磷酸化的机制通常始于一种叫做激酶的酶，它将高能供体分子（如ATP，腺苷三磷酸）上的磷酸基团转移到目标蛋白中的特定氨基酸残基上。磷酸基团通常来源于含有phosphoryl（磷酸基）的分子，这对于磷酸化过程至关重要。这种修饰可以改变蛋白质的功能、活性或在细胞内的位置，从而影响细胞行为。例如，当一种蛋白质通过添加phosphoryl（磷酸基）基团而被磷酸化时，它的构象可能会发生变化，使其能够与其他蛋白质或分子相互作用。这种相互作用可以启动信号级联反应，导致各种生理反应。因此，phosphoryl（磷酸基）基团充当分子开关，打开或关闭对细胞生存和功能至关重要的特定途径。除了激酶，另一类酶称为磷酸酶可以从蛋白质中去除磷酸基团，逆转磷酸化的效果。磷酸化与去磷酸化之间的这种动态平衡对于维持细胞内的稳态至关重要。这种平衡的破坏可能导致各种疾病，包括癌症、糖尿病和神经退行性疾病。因此，理解phosphoryl（磷酸基）在这些过程中的作用对于医学研究和治疗干预具有重要意义。此外，phosphoryl（磷酸基）基团的存在还可以影响蛋白质与DNA的相互作用。例如，被磷酸化的转录因子可能表现出增强或降低对特定基因启动子的结合亲和力，从而调节基因表达。这种调节机制突显了phosphoryl（磷酸基）在控制不仅是蛋白质功能而且是遗传活动中的重要性。总之，研究phosphoryl（磷酸基）及其在磷酸化中的作用是我们理解细胞过程的基础。随着研究继续揭示磷酸化的复杂性，越来越明显的是，phosphoryl（磷酸基）不仅仅是一个化学基团，而是细胞通讯复杂网络中的关键角色。通过探索磷酸化的机制和影响，科学家们可以深入了解健康和疾病，为针对这些基本生化途径的创新治疗和疗法铺平道路。