amyloidosis

简明释义

英[ˌæmɪlɔɪˈdəʊsɪs]美[ˌæməlɔɪˈdoʊsɪs]

n. [内科] 淀粉样变性

复 数 a m y l o i d o s e s

英英释义

单词用法

同义词

反义词

例句

1.Has anyone in your family ever been diagnosed with amyloidosis?

家里有人得过淀粉样变吗？

2.As the name implies, this form of amyloidosis is inherited. This type often affects the liver, nerves, heart and kidneys.

如其名，这种淀粉样变是遗传的，病变通常侵袭肝脏，神经，心脏和肾脏。

3.Primary amyloidosis isn't associated with other diseases - except for multiple myeloma, a form of bone marrow cancer.

原发性淀粉样变通常不伴有其他疾病——骨髓肉瘤(一种骨髓恶性肿瘤)除外。

4.Objective To improve the recognition of the primary systemic amyloidosis.

目的提高对原发性淀粉样变的认识。

5.And when amyloidosis affects the electrical system of your heart, this may disturb your heart's rhythm.

当淀粉样变侵袭心脏电传导系统，就会影响到心脏跳动的节律。

6.Cross's disease, familial amyloidosis, prevents the liver from breaking down a protein called transthyretin.

克罗斯患有一种其家族特有的淀粉样变性疾病，它使肝脏无法分解一种叫做转体基因的蛋白。

7.An uncertain proportion of patients, possibly about 10 per cent, have a third protein abnormality - amyloidosis.

还有一部分(比例不确定)病人可能占10%，有第三种异常蛋白——淀粉样变性。

8.Patients with amyloidosis often experience symptoms like fatigue and weight loss.

患有淀粉样变性的患者常常会出现疲劳和体重减轻的症状。

9.Research is ongoing to find better treatments for amyloidosis.

研究仍在进行中，以寻找更好的淀粉样变性治疗方法。

10.The doctor diagnosed her with amyloidosis, which is a condition where abnormal protein deposits accumulate in organs.

医生诊断她患有淀粉样变性，这是一种异常蛋白质沉积在器官中的疾病。

11.A biopsy may be necessary to confirm a diagnosis of amyloidosis.

可能需要进行活检以确认是否患有淀粉样变性。

12.Certain types of amyloidosis can affect the heart, leading to serious complications.

某些类型的淀粉样变性可能影响心脏，导致严重并发症。

作文

Amyloidosis is a rare but serious condition that occurs when a protein called amyloid builds up in the organs and tissues of the body. This abnormal accumulation can lead to various health problems, as it interferes with the normal functioning of the affected organs. Understanding amyloidosis (淀粉样变性) is crucial for both patients and healthcare providers, as early diagnosis and treatment can significantly improve outcomes.The amyloid protein is produced in the bone marrow and can be deposited in different areas of the body, including the heart, kidneys, liver, spleen, and nervous system. When these deposits accumulate, they can disrupt the normal structure and function of the organs, leading to symptoms that vary depending on which organs are affected. For example, if the heart is involved, patients may experience shortness of breath, irregular heartbeats, or swelling in the legs and ankles. On the other hand, kidney involvement can result in proteinuria, which is the presence of excess protein in the urine, and can ultimately lead to kidney failure.There are several types of amyloidosis (淀粉样变性), with the most common being AL amyloidosis, which is associated with certain blood disorders, and AA amyloidosis, which is linked to chronic inflammatory diseases. Other forms include hereditary amyloidosis, which is passed down through families, and wild-type amyloidosis, which typically affects older adults without any known underlying conditions.Diagnosing amyloidosis (淀粉样变性) can be challenging due to its rarity and the nonspecific nature of its symptoms. Doctors often rely on a combination of medical history, physical examinations, imaging tests, and biopsies to confirm the presence of amyloid deposits. A biopsy, where a small sample of tissue is taken from an affected organ, is usually the definitive way to diagnose this condition.Once diagnosed, treatment options for amyloidosis (淀粉样变性) depend on the type and severity of the disease. In some cases, managing the underlying condition that is causing the amyloid production can help reduce the amount of amyloid in the body. For instance, in AL amyloidosis, chemotherapy drugs used to treat the associated blood disorder may also help decrease amyloid levels. Additionally, supportive care, such as medications to manage heart failure or kidney issues, is essential for improving quality of life.Research into amyloidosis (淀粉样变性) is ongoing, with scientists exploring new therapies and treatments that target the amyloid protein itself. Some promising developments include monoclonal antibodies and small molecules that aim to prevent the formation of amyloid fibrils or promote their clearance from the body. These advancements offer hope for patients suffering from this complex and often misunderstood disease.In conclusion, amyloidosis (淀粉样变性) is a multifaceted condition that poses significant challenges for diagnosis and treatment. Awareness and understanding of this disease are critical for timely intervention and management. As research progresses, there is optimism that new therapeutic strategies will emerge, providing better outcomes for those affected by amyloidosis (淀粉样变性). It is essential for both patients and healthcare professionals to stay informed about this condition to ensure the best possible care.

淀粉样变性是一种罕见但严重的疾病，当一种叫做淀粉样蛋白的蛋白质在身体的器官和组织中积累时，就会发生这种情况。这种异常的积累可能导致各种健康问题，因为它干扰了受影响器官的正常功能。理解淀粉样变性（amyloidosis）对患者和医疗提供者来说至关重要，因为早期诊断和治疗可以显著改善结果。淀粉样蛋白是在骨髓中产生的，可以沉积在身体的不同部位，包括心脏、肾脏、肝脏、脾脏和神经系统。当这些沉积物累积时，它们会破坏器官的正常结构和功能，导致症状因受影响的器官而异。例如，如果心脏受到影响，患者可能会感到呼吸急促、心律不齐或腿部和脚踝肿胀。另一方面，肾脏受累可能导致蛋白尿，即尿液中存在过量蛋白质，并最终导致肾衰竭。淀粉样变性（amyloidosis）有几种类型，其中最常见的是AL型淀粉样变性，与某些血液疾病相关，以及AA型淀粉样变性，与慢性炎症性疾病相关。其他形式包括遗传性淀粉样变性，这种病是通过家族遗传的，以及老年型淀粉样变性，通常影响没有已知基础疾病的老年人。由于淀粉样变性（amyloidosis）的罕见性和其症状的非特异性，诊断可能具有挑战性。医生通常依靠医学历史、体检、影像学检查和活检的组合来确认淀粉样沉积的存在。活检是从受影响器官取出一小块组织样本，通常是确诊这种疾病的决定性方法。一旦确诊，淀粉样变性（amyloidosis）的治疗选择取决于疾病的类型和严重程度。在某些情况下，管理导致淀粉样产生的基础疾病可以帮助减少体内淀粉样的数量。例如，在AL型淀粉样变性中，用于治疗相关血液疾病的化疗药物也可能有助于降低淀粉样水平。此外，支持性护理，如管理心力衰竭或肾脏问题的药物，对于改善生活质量至关重要。关于淀粉样变性（amyloidosis）的研究仍在进行中，科学家们正在探索针对淀粉样蛋白本身的新疗法和治疗方法。一些有前景的发展包括单克隆抗体和小分子，旨在防止淀粉样纤维的形成或促进其从体内清除。这些进展为遭受这一复杂且常被误解的疾病的患者带来了希望。总之，淀粉样变性（amyloidosis）是一种多面的疾病，给诊断和治疗带来了重大挑战。提高对这种疾病的认识和理解对于及时干预和管理至关重要。随着研究的进展，人们乐观地认为将出现新的治疗策略，为那些受到淀粉样变性（amyloidosis）影响的人提供更好的结果。患者和医疗专业人员了解这种疾病至关重要，以确保最佳护理。