thrombin

简明释义

英[ˈθrɒmbɪn]美[ˈθrɑːmbɪn]

n. [生化] 凝血酶

英英释义

单词用法

同义词

反义词

例句

1.Objective To investigate the mechanism of brain injury caused by thrombin and the intervention effect of hirudin and nimodipine.

目的探讨凝血酶对脑组织损害的机制，及凝血酶抑制剂水蛭素和尼莫地平对其的影响。

2.The ultimate result is the formation of the thrombin and fibrin clot, and each enzymolysis accompaniment magnify effective.

最终结果是凝血酶和纤维蛋白凝块的形成，而且每步酶解反应均有放大效应。

3.When the tissue damage, the release of thromboplastin to prothrombin into thrombin.

当组织损伤时，释放出凝血致活酶，把凝血酶原变成凝血酶。

4.Objective To investigate the mechanism of brain injury caused by thrombin and the intervention effect of hirudin and nimodipine.

目的探讨凝血酶对脑组织损害的机制，及凝血酶抑制剂水蛭素和尼莫地平对其的影响。

5.Express ancrod, a snake venom thrombin-like enzyme, in methylotrophic yeast Pichia pastoris.

利用毕赤酵母表达具有生物学活性的蛇毒类凝血酶安克洛。

6.Based on the arginine esterase activity, the thrombin-like enzyme accounted for about 60% of the total.

其中类凝血酶的精氨酸酯酶活力最高，约占总酯酶活力的60%。

7.In the coagulation cascade, thrombin plays a central role.

在凝血级联反应中，凝血酶发挥着核心作用。

8.The conversion of fibrinogen to fibrin is facilitated by thrombin.

纤维蛋白原转化为纤维蛋白的过程由凝血酶促进。

9.Anticoagulants work by inhibiting the activity of thrombin.

抗凝药物通过抑制凝血酶的活性来发挥作用。

10.The activation of thrombin is crucial for blood clotting.

激活凝血酶对血液凝固至关重要。

11.Doctors monitor thrombin levels to assess a patient's coagulation status.

医生监测凝血酶水平以评估患者的凝血状态。

作文

Thrombin is a crucial enzyme in the human body that plays a significant role in the process of blood coagulation. When a blood vessel is injured, the body initiates a complex series of events to prevent excessive bleeding. One of the key players in this process is thrombin, which is produced from prothrombin, a plasma protein. The conversion of prothrombin to thrombin occurs through the action of various clotting factors, primarily factor Xa. Once formed, thrombin (凝血酶) acts on fibrinogen, converting it into fibrin, which forms a mesh-like structure that helps to stabilize the blood clot. This transformation is vital because it provides a scaffold for platelets and other cells to gather, effectively sealing the wound and allowing the healing process to begin.In addition to its role in clot formation, thrombin (凝血酶) also has several other important functions. It activates platelets, which are essential for forming clots, and stimulates the release of additional clotting factors from the platelets themselves. This creates a positive feedback loop that amplifies the clotting response, ensuring that bleeding is quickly controlled. Furthermore, thrombin (凝血酶) can influence inflammation and tissue repair processes, indicating its multifaceted role in maintaining hemostasis and promoting recovery after injury.Understanding the function of thrombin (凝血酶) is critical in medical settings, particularly in surgeries and trauma care. If thrombin (凝血酶) activity is insufficient, patients may experience prolonged bleeding, while excessive activity can lead to thrombosis, a condition where blood clots form inappropriately within blood vessels. This duality underscores the importance of balanced thrombin levels in the body.In recent years, research has focused on developing therapies that target thrombin (凝血酶) for both bleeding disorders and thrombotic conditions. For instance, anticoagulants such as direct thrombin inhibitors have been designed to reduce the risk of clot formation in patients at high risk for stroke or heart attack. Conversely, pro-coagulant therapies aim to enhance thrombin activity in patients who suffer from hemophilia or other bleeding disorders. Such advancements highlight the ongoing need for a deeper understanding of thrombin (凝血酶) and its pathways.In conclusion, thrombin (凝血酶) is more than just a component of the coagulation cascade; it is a pivotal enzyme that facilitates wound healing and maintains hemostatic balance. Its intricate functions extend beyond clot formation, impacting various physiological processes. As research continues to unveil the complexities of thrombin (凝血酶), it becomes increasingly clear that this enzyme holds the key to managing both bleeding and clotting disorders, ultimately improving patient outcomes in clinical practice.