homozygosity

简明释义

英[ˌhəʊməʊzaɪˈɡɒsəti]美[hoʊmoʊzaɪˈɡɑːsətɪ]

n. 纯合性，纯质性

英英释义

单词用法

同义词

反义词

例句

1.Objective To evaluate the role of homozygosity mapping in the fine mapping of the genes responsible for the rare autosomal recessive diseases.

目的探讨纯合子定位法在罕见常染色体隐性遗传病致病基因精确定位中的作用。

2.The study also indicated that homozygosity by selfing could significantly enhance the mean resistance level of O. rufipogon and O. officinalis.

研究还表明，自交提纯能够明显提高这两种野生稻的平均抗性水平。

3.The study also indicated that homozygosity by selfing could significantly enhance the mean resistance level of O. rufipogon and O. officinalis.

研究还表明，自交提纯能够明显提高这两种野生稻的平均抗性水平。

4.The genetic test revealed a significant degree of homozygosity in the patient’s genome.

基因检测显示患者基因组中存在显著程度的homozygosity。

5.The study of homozygosity can help identify genetic disorders in families.

对homozygosity的研究可以帮助识别家族中的遗传疾病。

6.Researchers found that homozygosity is associated with certain traits in plants.

研究人员发现，homozygosity与植物的某些性状相关。

7.In genetics, homozygosity refers to having two identical alleles for a particular gene.

在遗传学中，homozygosity 指的是在某个特定基因上拥有两个相同的等位基因。

8.High levels of homozygosity in a population can indicate inbreeding.

在人口中，高水平的homozygosity可能表明近亲繁殖。

作文

In the field of genetics, the term homozygosity refers to the presence of two identical alleles for a particular gene in an organism. This genetic configuration can have significant implications for an individual's traits and health. Understanding homozygosity is crucial for researchers working in various areas, including evolutionary biology, medicine, and conservation genetics. To start with, homozygosity can arise through several mechanisms, such as inbreeding or the selection of specific traits over generations. When individuals with similar genetic backgrounds mate, the likelihood of producing offspring with homozygosity increases. This phenomenon is particularly relevant in small populations where genetic diversity is limited. The consequences of homozygosity can be both beneficial and detrimental. On one hand, it can lead to the expression of desirable traits, such as disease resistance or improved physical characteristics. For example, in agricultural practices, plant breeders often seek to create homozygous lines that exhibit uniformity and stability in crop yields. On the other hand, high levels of homozygosity can result in the expression of harmful recessive traits. This is especially concerning in endangered species, where reduced genetic variation can lead to increased susceptibility to diseases and environmental changes. Moreover, studies have shown that homozygosity can be associated with certain genetic disorders in humans. Conditions such as cystic fibrosis and sickle cell anemia are examples of diseases that occur due to the inheritance of two identical recessive alleles. Genetic counseling often emphasizes the importance of understanding homozygosity for individuals who may be carriers of such conditions, highlighting the need for awareness and testing. In conservation genetics, the concept of homozygosity plays a critical role in managing endangered species. Conservationists strive to maintain genetic diversity within populations to avoid the pitfalls of homozygosity. Strategies such as habitat preservation, wildlife corridors, and managed breeding programs aim to enhance genetic variability and reduce the risks associated with inbreeding. By promoting genetic diversity, conservation efforts can help ensure the long-term survival of vulnerable species. In conclusion, homozygosity is a fundamental concept in genetics that carries significant implications for various fields, including agriculture, medicine, and conservation. While it can lead to advantageous traits, it also poses risks, particularly in small populations and among endangered species. A comprehensive understanding of homozygosity is essential for researchers and practitioners alike, as they navigate the complexities of genetic inheritance and its effects on health and biodiversity. As we continue to explore the genetic landscape, the study of homozygosity will remain a vital area of research, contributing to advancements in science and our understanding of life itself.

在遗传学领域，术语homozygosity指的是一个生物体中特定基因的两个等位基因相同的存在。这种遗传配置对个体的特征和健康有重要影响。理解homozygosity对于在进化生物学、医学和保护遗传学等多个领域工作的研究人员至关重要。首先，homozygosity可以通过几种机制产生，例如近亲繁殖或在几代中选择特定特征。当具有相似遗传背景的个体交配时，产生具有homozygosity的后代的可能性增加。这种现象在小种群中特别相关，因为遗传多样性有限。homozygosity的后果可能是有利的，也可能是有害的。一方面，它可以导致优良特征的表现，例如抗病能力或改善的身体特征。例如，在农业实践中，植物育种者通常希望创建表现出作物产量均匀性和稳定性的homozygous品系。另一方面，高水平的homozygosity可能导致有害隐性特征的表现。这在濒危物种中尤其令人担忧，因为遗传变异的减少可能导致对疾病和环境变化的易感性增加。此外，研究表明，homozygosity与某些人类遗传疾病有关。例如，囊性纤维化和镰状细胞贫血就是由于继承了两个相同的隐性等位基因而发生的疾病。遗传咨询通常强调理解homozygosity的重要性，特别是对于可能携带这些疾病的个体，这突显了意识和检测的必要性。在保护遗传学中，homozygosity的概念在管理濒危物种中发挥着关键作用。保护工作者努力保持种群中的遗传多样性，以避免homozygosity所带来的陷阱。栖息地保护、野生动物走廊和管理繁殖计划等策略旨在增强遗传变异，减少近亲繁殖带来的风险。通过促进遗传多样性，保护工作可以帮助确保脆弱物种的长期生存。总之，homozygosity是遗传学中的一个基本概念，对农业、医学和保护等多个领域具有重要意义。虽然它可能导致有利特征，但在小种群和濒危物种中也会带来风险。全面理解homozygosity对于研究人员和从业者来说至关重要，因为他们在应对遗传遗传和其对健康及生物多样性影响的复杂性。随着我们继续探索遗传景观，homozygosity的研究将仍然是一个重要的研究领域，为科学进步和我们对生命本身的理解做出贡献。