aminopterin

简明释义

英[ˌæmɪnˈpɒtərɪn]美[ˌæmɪnˈpɒtərɪn]

n. 氨喋呤

英英释义

单词用法

同义词

反义词

例句

1.He treated these cells with a drug, aminopterin.

他用氨基喋呤来处理这些细胞。

2.In the last days of the year, Farber injected his patient with an experimental drug, aminopterin, and within two weeks he was walking, talking and eating again.

在那年最后的日子里，法伯给他的病人注射了一种还处于试验阶段的药物氨基喋呤。不到两个星期，男孩又能走路、聊天和吃饭了。

3.In the last days of the year, Farber injected his patient with an experimental drug, aminopterin, and within two weeks he was walking, talking and eating again.

在那年最后的日子里，法伯给他的病人注射了一种还处于试验阶段的药物氨基喋呤。不到两个星期，男孩又能走路、聊天和吃饭了。

4.The mechanism of action of aminopterin 氨基甲酰苯胺 involves inhibition of folate metabolism.

氨基甲酰苯胺aminopterin的作用机制涉及对叶酸代谢的抑制。

5.Clinical trials are evaluating the safety of aminopterin 氨基甲酰苯胺 in combination with other drugs.

临床试验正在评估氨基甲酰苯胺aminopterin与其他药物联合使用的安全性。

6.Doctors prescribed aminopterin 氨基甲酰苯胺 for a patient with severe psoriasis.

医生为一名重度银屑病患者开了氨基甲酰苯胺aminopterin。

7.Researchers are studying the effects of aminopterin 氨基甲酰苯胺 on cancer cell proliferation.

研究人员正在研究氨基甲酰苯胺aminopterin对癌细胞增殖的影响。

8.The use of aminopterin 氨基甲酰苯胺 in treating autoimmune diseases has shown promising results.

在治疗自身免疫性疾病中使用氨基甲酰苯胺aminopterin显示出良好的效果。

作文

Aminopterin is a drug that has played a significant role in the field of medicine, particularly in cancer treatment and the management of autoimmune diseases. It is classified as an antifolate agent, which means it inhibits the action of folic acid in the body. This property makes aminopterin (阿米诺喹啉) effective in disrupting the growth of rapidly dividing cells, such as cancer cells. The discovery of aminopterin dates back to the 1940s when it was initially used to treat leukemia in children, marking a breakthrough in pediatric oncology.The mechanism of action of aminopterin involves the inhibition of dihydrofolate reductase, an enzyme crucial for the synthesis of nucleotides, which are the building blocks of DNA and RNA. By blocking this enzyme, aminopterin (阿米诺喹啉) effectively starves cancer cells of the necessary components needed for their replication and survival. This targeted approach not only helps in shrinking tumors but also in prolonging the lives of patients diagnosed with various types of cancers.In addition to its use in cancer therapy, aminopterin has been explored for its potential in treating certain autoimmune diseases, such as rheumatoid arthritis. The immunosuppressive properties of aminopterin (阿米诺喹啉) can help reduce inflammation and the overactive immune response that characterizes these conditions. However, the use of aminopterin must be carefully monitored due to its potential side effects, which can include bone marrow suppression, leading to increased susceptibility to infections.Despite the challenges associated with its use, aminopterin remains a cornerstone in the development of chemotherapy regimens. Its effectiveness has paved the way for the creation of newer antifolate drugs that aim to enhance the therapeutic effects while minimizing adverse reactions. Research continues to explore the full potential of aminopterin (阿米诺喹啉) in combination therapies, where it is used alongside other agents to improve patient outcomes.The historical significance of aminopterin cannot be overstated. It was one of the first drugs to demonstrate that targeting specific metabolic pathways could lead to effective cancer treatments. This realization has inspired countless studies and clinical trials aimed at finding more effective therapies for cancer and other diseases. As researchers delve deeper into the molecular mechanisms of aminopterin (阿米诺喹啉), they uncover new insights that could lead to innovative treatment strategies and improved patient care.In conclusion, aminopterin is more than just a pharmaceutical compound; it represents a pivotal advancement in medical science. Its journey from a laboratory discovery to a life-saving treatment exemplifies the power of scientific inquiry and innovation. As we continue to understand and harness the capabilities of aminopterin (阿米诺喹啉), we move closer to conquering some of the most challenging health issues of our time.