arginase

简明释义

英[ˈɑːdʒɪˌneɪz]美[ˈɑrdʒəˌnes;ˈɑrdʒəˌnez]

n. [生化] 精氨酸酶

英英释义

单词用法

同义词

反义词

例句

1.The recent progress of boronic acid derivatives used as enzyme inhibitors is reviewed focused on the serine protease inhibitors, proteasome inhibitors, and arginase inhibitors.

综述了有机硼酸类化合物作为酶抑制剂的研究进展，重点介绍了近年来发现的丝氨酸蛋白酶抑制剂、蛋白酶体抑制剂和精氨酸酶抑制剂。

2.Expressions of S-adenosylmethionine synthetase gene, arginase gene and oxidant stress related genes in myocardial tissue of normal and diabetic rats were assayed by DNA microarray.

在正常大鼠和糖尿病大鼠心肌组织中，以基因芯片技术测定s腺苷蛋氨酸合成酶、精氨酸酶及氧化应激相关基因的表达。

3.Expressions of S-adenosylmethionine synthetase gene, arginase gene and oxidant stress related genes in myocardial tissue of normal and diabetic rats were assayed by DNA microarray.

在正常大鼠和糖尿病大鼠心肌组织中，以基因芯片技术测定s腺苷蛋氨酸合成酶、精氨酸酶及氧化应激相关基因的表达。

4.In this study, the chiral selectivity of arginase was investigated by means of molecular dynamics and molecular docking.

本文运用分子对接和分子动力学模拟的方法，对精氨酸酶进行手性选择性研究。

5.Arginase activity is a key diagnostic indicator. Increased levels of arginase activity in blood have been associated with liver damage.

精氨酸酶活性是临床诊断的关键指标，血液中精氨酸酶活性高意味着有肝功能损伤。

6.Arginase catalyzes the conversion of arginine to ornithine and urea, completing the last step in the urea cycle.

精氨酸酶催化精氨酸转化成鸟氨酸和尿素，且是尿素循环的最后一步。

7.The role of arginase in wound healing is being actively studied.

对精氨酸酶在伤口愈合中的作用正在积极研究。

8.Research shows that arginase levels can affect nitric oxide production.

研究表明，精氨酸酶的水平会影响一氧化氮的产生。

9.Inhibition of arginase might enhance immune responses.

抑制精氨酸酶可能增强免疫反应。

10.High activity of arginase has been linked to certain cancers.

高活性的精氨酸酶与某些癌症有关。

11.The enzyme arginase is crucial for the urea cycle in the liver.

酶精氨酸酶对肝脏中的尿素循环至关重要。

作文

Arginase is an important enzyme in the urea cycle, which plays a crucial role in the metabolism of arginine, an amino acid that is vital for various physiological functions. In simple terms, arginase（精氨酸酶） catalyzes the hydrolysis of arginine to produce urea and ornithine. This reaction is essential because it helps to eliminate excess nitrogen from the body, which can be toxic if accumulated. The significance of arginase（精氨酸酶） extends beyond just nitrogen elimination; it also influences several biological pathways, including the synthesis of polyamines and nitric oxide, both of which are critical for cell growth and signaling.Understanding the function of arginase（精氨酸酶） is particularly important in the context of various diseases. For instance, elevated levels of arginase（精氨酸酶） have been associated with certain types of cancer. Cancer cells often exhibit altered metabolism, and the increased activity of arginase（精氨酸酶） can lead to reduced availability of arginine, which is necessary for T-cell function. This can result in immune suppression, allowing cancer cells to evade the immune response. Therefore, targeting arginase（精氨酸酶） has emerged as a potential therapeutic strategy in cancer treatment.Furthermore, arginase（精氨酸酶） is also implicated in other health conditions, such as cardiovascular diseases and liver dysfunction. In cardiovascular diseases, the balance between nitric oxide production and arginase activity is crucial. Nitric oxide is a vasodilator that helps maintain blood vessel health, while excessive arginase（精氨酸酶） activity can lead to decreased nitric oxide levels, contributing to hypertension and atherosclerosis. Similarly, in liver diseases, alterations in arginase（精氨酸酶） activity can affect ammonia detoxification and overall metabolic homeostasis.Research into arginase（精氨酸酶） has also revealed its potential role in neurodegenerative diseases. Studies have shown that increased levels of arginase（精氨酸酶） in the brain may contribute to neuroinflammation and neuronal damage. By understanding how arginase（精氨酸酶） affects neurobiology, scientists hope to develop new strategies for treating diseases such as Alzheimer's and Parkinson's.In conclusion, arginase（精氨酸酶） is not just a simple enzyme involved in the urea cycle; it has far-reaching implications for human health. Its role in cancer, cardiovascular diseases, liver dysfunction, and neurodegenerative disorders highlights the importance of this enzyme in various metabolic processes. As research continues to evolve, understanding the multifaceted roles of arginase（精氨酸酶） will be crucial for developing novel therapeutic approaches that can improve patient outcomes across a spectrum of diseases.