progeria

简明释义

英[/prəˈdʒɪəriə/]美[/prəˈdʒɪəriə/]

n. 儿童的早衰症；早衰，早老

英英释义

单词用法

同义词

反义词

例句

1.He had a disease called Progeria.

他得了一种叫作儿童早衰症的病。

2.Strong Will - I chose this as one of the qualities because John Tacket lived to be the oldest person with progeria in America.

坚强的意志——因为John是美国早衰症患者中存活最久的人。

3.These were found to reverse an abnormality in progeria cells in the laboratory and also prevented symptoms developing in progeria mice.

这种药物在实验室中被发现可以抑制早衰细胞的变异，并在实验鼠身上产生了预期效果。

4.Hayley is one of the first progeria children to try a new class of drug called FTIs (farnesyltransferase inhibitors).

海莉是第一批接受一种最新抑制剂药物治疗的早衰症患儿。

5.According to el comercio May 25, in Cajamarca, Peru, an 8-year-old girl suffers from hutchinson-gilford progeria syndrome (HGPS) which makes her look like an 80-year-old grandma.

据秘鲁《商报》5月25日报道，秘鲁卡哈马卡省的一位8岁女童阿拉塞莉-迪亚斯患上了罕见的儿童早衰症，其模样看上去像80岁的老奶奶。

6.TWO common drugs have reversed the effects in mice of progeria, a rare genetic disease that causes premature ageing.

两种普通药对实验老鼠的早衰症有效，而早衰症是是一种罕见的遗传性疾病。

7.They had a condition called progeria, meaning that they aged much more rapidly than normal mice.

它们的症状也称早老症，意味着它们比一般的小白鼠衰老的更快。

8.According to el comercio May 25, in Cajamarca, Peru, an 8-year-old girl suffers from hutchinson-gilford progeria syndrome (HGPS) which makes her look like an 80-year-old grandma.

据秘鲁《商报》5月25日报道，秘鲁卡哈马卡省的一位8岁女童阿拉塞莉-迪亚斯患上了罕见的儿童早衰症，其模样看上去像80岁的老奶奶。

9.Living with progeria can be challenging for both patients and their families.

与早衰症共存对患者及其家人来说可能是一个挑战。

10.Research on progeria has provided insights into the aging process in humans.

对早衰症的研究为人类衰老过程提供了见解。

11.Doctors are studying the genetic causes of progeria to develop potential treatments.

医生正在研究早衰症的遗传原因，以开发潜在的治疗方法。

12.Children with progeria often age at an accelerated rate, leading to various health complications.

患有早衰症的儿童通常以加速的速度衰老，导致各种健康并发症。

13.The symptoms of progeria can include hair loss and joint stiffness.

早衰症的症状可能包括脱发和关节僵硬。

作文

Progeria is a rare genetic disorder that causes children to age rapidly. The medical term for this condition is Hutchinson-Gilford Progeria Syndrome (HGPS). Children with progeria experience symptoms that resemble normal aging, but they do so at an accelerated pace. This means that while most children are enjoying their youth, those affected by progeria may face challenges typically associated with much older individuals. For example, they may develop conditions such as arthritis, cardiovascular disease, and hair loss, all of which are usually seen in older adults. The cause of progeria lies in a mutation of the LMNA gene, which plays a crucial role in maintaining the structure of the cell nucleus. This mutation leads to the production of an abnormal protein called progerin, which destabilizes the nuclear envelope and results in cellular damage. As a result, children with progeria experience accelerated cellular aging, which contributes to their physical appearance and health issues. One of the most heart-wrenching aspects of progeria is its impact on the lives of those affected and their families. Children with this condition often look significantly older than their peers, which can lead to social isolation and discrimination. They may find it difficult to form friendships or participate in regular childhood activities due to their health limitations and the misconceptions others may have about their condition. Despite these challenges, many families of children with progeria are determined to raise awareness about the condition. Organizations such as the Progeria Research Foundation work tirelessly to fund research aimed at understanding progeria better and finding potential treatments. Advances in medical research have led to promising developments, including the use of drugs that target the effects of progerin. These treatments aim to improve the quality of life for children with progeria and potentially extend their lifespan. The emotional toll of progeria cannot be understated. Many children with this condition face the reality of a shortened lifespan, with most living into their teenage years or early twenties. This knowledge can be devastating for both the children and their families. However, it is essential to focus on the positive aspects of life and cherish the time spent together. Families often emphasize the importance of creating lasting memories and celebrating each milestone, no matter how small. In conclusion, progeria is a complex and challenging condition that affects not only the children diagnosed with it but also their families and communities. Through education, awareness, and continued research, we can work towards a future where children with progeria can live longer, healthier lives. It is crucial to foster an environment of support and understanding, ensuring that those affected by progeria are treated with dignity and respect. As we learn more about this condition, we hope to unlock the mysteries of aging itself, benefitting not only those with progeria but humanity as a whole.

早老症是一种罕见的遗传疾病，导致儿童迅速衰老。这种情况的医学术语是哈钦森-吉尔福德早老症综合症（HGPS）。患有早老症的儿童会经历类似于正常衰老的症状，但他们的衰老速度却加快。这意味着，当大多数儿童享受他们的青春时，受到早老症影响的儿童可能面临通常与年长者相关的挑战。例如，他们可能会发展出关节炎、心血管疾病和脱发等病症，这些通常是在老年人中出现的。早老症的原因在于LMNA基因的突变，该基因在维持细胞核结构中起着至关重要的作用。这种突变导致一种异常蛋白质——早老蛋白的产生，破坏了核膜的稳定性，导致细胞损伤。因此，患有早老症的儿童经历了加速的细胞衰老，这使他们的外貌和健康问题得以显现。早老症最令人心碎的方面之一是它对受影响者及其家庭生活的影响。患有这种疾病的儿童往往看起来比同龄人年长得多，这可能导致社会孤立和歧视。他们可能由于健康限制和他人对其状况的误解而难以建立友谊或参与正常的儿童活动。尽管面临这些挑战，许多患有早老症儿童的家庭决心提高人们对这种疾病的认识。诸如早老症研究基金会等组织不懈努力，为了解早老症并寻找潜在治疗方案的研究提供资金支持。医学研究的进展带来了有希望的发展，包括使用针对早老蛋白效应的药物。这些治疗旨在改善患有早老症儿童的生活质量，并可能延长他们的寿命。早老症的情感负担不可低估。许多患有这种疾病的儿童面临着缩短生命的现实，大多数人活到青少年或二十出头。这种认知对儿童和他们的家庭来说都是毁灭性的。然而，专注于生活的积极方面并珍惜共度的时光是至关重要的。家庭常常强调创造持久记忆和庆祝每一个里程碑的重要性，无论这个里程碑有多小。总之，早老症是一种复杂且具有挑战性的疾病，不仅影响被诊断的儿童，还影响他们的家庭和社区。通过教育、意识和持续的研究，我们可以朝着一个未来努力，让患有早老症的儿童能够过上更长、更健康的生活。培养支持和理解的环境至关重要，确保那些受到早老症影响的人受到尊严和尊重。随着我们对这种疾病了解的深入，我们希望揭开衰老本身的奥秘，使不仅是早老症患者受益，而是整个人类。